1000ft view part 2 Flashcards

1
Q

How many lobes are in the liver

A

4 lobes

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2
Q

What is the Couinaud classification

A

The functional anatomy breaks the liver into 9 sections

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3
Q

What is the porta hepatis

A

Where the hepatic artery, portal vein, left/right hepatic duct enter

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4
Q

What covers the outside of the liver

A

Glisson capsule
*contains neuromuscular supply

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5
Q

What part of the liver is not covered by peritoneum

A

Posteriorly

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6
Q

What separated the right and left and right lobes of the liver

A

Falciform ligament
*attaches to anterior abdominal wall

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7
Q

What is the ligamentum teres (Round ligament) of the liver

A

Extension off the falciform ligament that attaches to umbilicus

Remnant of the umbilical vein

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8
Q

What attaches the liver to the diaphragm

A

Coronary ligament

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9
Q

How much of the CO goes to the liver

A

25%

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10
Q

How much venous blood is in the liver

A

1000-1200mL/min

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11
Q

How much arterial blood is in the liver

A

400-500 mL/min

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12
Q

What is the functional unit of the liver

A

liver lobule

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13
Q

What type of cells make up the liver lobule

A

hepatocytes

*functional unit for protein production

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14
Q

What are sinusoids in the liver

A

capillaries between hepatocytes that receive both arterial and venous blood

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15
Q

Where do sinusoids drain

A

central vein which then drains into hepatic vein -> IVC

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16
Q

What is the hepatic triad

A

Bile ductule
branch of portal vein
branch of hepatic artery

17
Q

What are Kupffer cells

A

phagocytes
*#1 nom nom cells in the body but stay in the liver

18
Q

Where are kupffer cells found

A

in the sinusoids of the liver

19
Q

What makes up bile

A

bile salts (acids)
cholesterol
bilirubin
electrolytes
water

20
Q

What is the ampulla of vater

A

Where the gallbladder connects to the duodenum and the area just before the sphincter of oddi

21
Q

Where do bile salts get reabsorbed

A

terminal ileum and then returned to portal circulation

22
Q

What is heme converted to before entering plasma

23
Q

What type of bilirubin is lipid soluble

A

unconjugated (bound to albumin)

24
Q

What happens with conjugated bilirubin

A

turns into bile (green/black color)

25
What does glucagon do in the body
increased cardiac contraction increase renal blood flow increase bile excretion stops gastric acid secretion
26
When do glucagon levels increase
during exercise
27
What does the liver make
bile albumin
28
What is albumin needed for
transport of hormones, fats, nutrients, meds maintain intravascular volume (osmotic pressure)
29
Where are most of the clotting factors made
liver -Fibrinogen -Thrombin -Vit K clotting factors - Thrombopoetin
30
What factors does the liver make to help break down clots
plasminogen antithrombin
31
What does the liver make to help with blood pressed
Angiotensinogen
32
What immune proteins does the liver make
Complement proteins C-reactive peptide
33
What will the hepatocytes do in the liver
Breakdown toxic substances
34
What is the product of protein breakdown in the body
Ammonia *concerned about this level in alcoholics
35
What is vitamin D necessary for
calcium absorption
36
What is responsible for protein breakdown
trypsin chymotrypsin