10-Paramyxo and Coronaviruses

Question 1

What are a common feature of paramyxoviruses; good way to infect cells by cell-to-cell spread; good way to escape neutralizing antibodies?

Answer 1

syncytia

Question 2

How do paramyxoviruses travel from URT to LRT?

Answer 2

forming syncytium

Question 3

How is (RSV) Respiratory Syncytial Virus spread?

Answer 3

person to person via respiratory droplets - winter/spring seasonality

Question 4

What is the incubation period for RSV?

Answer 4

2-4 days starts with URT

Question 5

What is the #1 cause of LRT infections in children

Answer 5

RSV

Question 6

What is the name of the treatment for RSV; monoclonal antibody to the surface protein of RSV?

Answer 6

Palivizumab

Question 7

What is caused by one of the types of (PIV) Parainfluenza Virus, resulting in inflammation of the larynx and trachea?

Answer 7

croup

Question 8

One type of PIV can cause serious respiratory infection in young children like…

Answer 8

Bronchitis and pneumonia

Question 9

What are the major defining things about mumps?

Answer 9

swelling of the parotid (salivary) gland

testicular swelling in ~10% of infected men

Question 10

What kind of vaccine is used to prevent Mumps?

Answer 10

attenuated-live virus vaccine

Question 11

What are the 3 C’s of Measles?

Answer 11

Cough, Coryza, Conjunctivitis

Question 12

What is indicative of Measles and is on the buccal membrane, opposite the 2nd molar and can cover the entire mucus membrane of mouth?

Answer 12

Koplik Spots

Question 13

What kind of vaccine is used for Measles?

Answer 13

live-attenuated vaccine

Question 14

What is a type of Rubella that becomes a problem if infected during the 1st trimester of pregnancy?

Answer 14

Congenital Rubella Syndrome

Question 15

What is the vaccine for Rubella?

Answer 15

Live attenuated - part of MMR

Question 16

What virus is 2nd in causing the common cold?

Answer 16

Human Corona Virus (HCoV)