10. Embryology, Pregnancy, + Lactation Flashcards

1
Q

What is fertilization?

A

The union of the nuclei of a sperm and an ovum, forming a zygote.

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2
Q

Where does fertilization typically occur?

A

In the outer third of the fallopian tube.

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3
Q

How long after ovulation can fertilization occur?

A

Within 12 to 24 hours.

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4
Q

What is a zygote?

A

A fertilized egg with a diploid number of chromosomes (2n).

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5
Q

What is implantation?

A

Attachment of the blastocyst to the endometrium about 6–8 days post-fertilization.

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6
Q

What hormone does the trophoblast produce?

A

Human chorionic gonadotropin (hCG).

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7
Q

What is the role of hCG in pregnancy?

A

Maintains the corpus luteum to keep secreting progesterone and estrogen.

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8
Q

When does the placenta begin to form?

A

After implantation, from the chorion and endometrium.

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9
Q

What are the three primary germ layers?

A

Ectoderm, mesoderm, and endoderm.

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10
Q

What does the ectoderm form?

A

Nervous system, skin, and related structures.

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11
Q

What does the mesoderm form?

A

Muscles, bones, circulatory system, kidneys.

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12
Q

What does the endoderm form?

A

Lining of the digestive, respiratory, and urogenital systems.

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13
Q

What are the extra-embryonic membranes?

A

Chorion, amnion, yolk sac, and allantois.

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14
Q

What is the function of the chorion?

A

Forms part of the placenta and secretes hCG.

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15
Q

What is the function of the amnion?

A

Provides cushioning and maintains temperature with amniotic fluid.

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16
Q

What does the yolk sac contribute to in humans?

A

Forms part of the umbilical cord and provides early blood cells.

17
Q

What is the role of the allantois?

A

Forms the stalk of the umbilical cord and contributes to the bladder.

18
Q

What is the placenta?

A

A temporary organ for nutrient, gas, and waste exchange between mother and fetus.

19
Q

What hormones does the placenta produce?

A

Estrogen, progesterone, and hCG.

20
Q

What is the umbilical cord made of?

A

1 vein (to fetus), 2 arteries (from fetus), formed by allantois and yolk sac.

21
Q

What is the function of fetal circulation?

A

To bypass non-functional fetal lungs and deliver oxygenated blood from placenta.

22
Q

What does the foramen ovale do?

A

Allows blood to flow from the right atrium to the left atrium, bypassing the lungs.

23
Q

What does the ductus arteriosus do?

A

Connects pulmonary trunk to aorta to bypass the lungs.

24
Q

What is the ductus venosus?

A

A vessel that allows oxygenated blood from the umbilical vein to bypass the liver.

25
What changes occur after birth in circulation?
Foramen ovale → fossa ovalis; ductus arteriosus → ligamentum arteriosum; vessels close off.
26
What is parturition?
The act of giving birth (childbirth).
27
What hormonal changes trigger labor?
Estrogen rises and progesterone drops, increasing oxytocin receptors in the uterus.
28
What does oxytocin do during labor?
Stimulates strong uterine contractions (positive feedback loop).
29
What are the three stages of childbirth?
Dilation, expulsion (birth), and placental stage (afterbirth).
30
What is pulmonary surfactant?
A substance that reduces surface tension in alveoli, produced from week 26–28 by fetal lungs.
31
What triggers the first breath after birth?
Low oxygen, high CO2, thoracic compression, and stimulation of the medulla.
32
What stimulates milk production?
Prolactin, which increases after childbirth when estrogen and progesterone drop.
33
What triggers milk ejection?
Oxytocin released in response to suckling.