10. Brain and behaviour Flashcards

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1
Q

What is the Theory of memory I: Stages?

A

Memory is a construct, for which there are many stages:
• Registration - input from our sense into the memory system
• Encoding - processing and combining of received information
• Storage - holding of that input in the memory system
• Retrieval

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2
Q

What is the Theory of memory II: Duration?

A

There are conceptual divisions in memory systems based upon how long a memory lasts:
• Sensory - seconds
• Working/short-term - few minutes
• Long-term - indefinite period of time with infinite capacity

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3
Q

Can information be transferred directly to long-term memory?

A

Yes, depending on what it is e.g. sensory aspects of traumatic memories

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4
Q

Which part of the brain is highly activated in traumatic moments?

A

Limbic system - very important in memory too

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5
Q

How can we overcome the disadvantageous effect of sensory information of traumatic events in our long-term memory?

A

• Overcome the nature of the memory
- make it less sensory and more verbally accessible
• This avoids simple sensory stimuli triggering sad and upsetting memories

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6
Q

Which parts of our sensory experiences are more likely to pass into working (short-term) memory?

A

Parts that we attend to

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7
Q

How can we increase the chance of transferring sensory experiences into working memory?

A

Rehearsing (this can then be stored and put into long-term memory)

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8
Q

What is retrieval, is it active or passive, and what type of memory allows this?

A
  • Recovering stored information from the (long-term) memory system
  • Active process
  • Working memory allows this retrieval process
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9
Q

What are the 2 types of long-term memory (Theory of memory III)? Describe them and their further subtypes

A

Declarative - available to conscious retrieval and can be declared (propositional)
• Episodic - what did I eat for breakfast?
• Semantic - what is the capital of Spain? (knowledge)
• Working - what did I just say? (short-term)

Non-declarative - causes experience-induced change in behaviour, and can’t be declared (procedural)
• Priming - subliminal advertising
• Skills - how to ride a bike
• Conditioning - phobias

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10
Q

What questions can you ask a patient to asses their memory?

A
Do you have difficulties with:
• remembering conversations?
• losing track of conversations?
• repeating questions/information?
• finding your way in familiar areas?
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11
Q

What questions can you ask to check recent episodic memory?

A
  • What did you have for dinner last night?
  • What are some of the headlines in the news?
  • How is your team doing at the moment?
  • How did you get here?
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12
Q

What happened when Henry Molaison underwent surgery for uncontrollable epileptic seizures?

A
  • Had specific lesions in the medio-temporal lobes, so his hippocampi were removed
  • Developed significant anterograde (and some retrograde) amnesia after surgery
  • Seizure vanished, but so did his ability to develop memories
  • Could learn new skills and recall general aspects of life, but couldn’t remember new experiences (like episodic and semantic memory)
  • Working and procedural memory was fine
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13
Q

Which parts of the brain does episodic memory involve?

A
Medial temporal lobes
• Hippocampus
• Entorhinal cortex
• Mammilary bodies
• Parahippocampal cortex
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14
Q

Which memory system is important in knowing how to do things?

A

Procedural

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15
Q

Which part of the brain plays a key role in learning motor tasks?

A

Cerebellum

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16
Q

Is the left or right hemisphere more concerned with verbal information processing?

A

Left

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17
Q

Which part of the brain do theories suggest is important for processing new information and activating memory (remembering)?

A

Hippocampus (different evidence shows it may be one or the other, or both)

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18
Q

What is the serial position effect, with reference to repeating a list of words back to a person?

A

This is where we tend to remember the words towards the beginning and end of the list

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19
Q

What factors is the probability of recalling a word related to?

A
  • Order in the list
  • Personal salience of words
  • Number of words
  • Chunking or other encoding strategy
  • Delay time
  • Distraction
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20
Q

In consultations, we give large amounts of information to patients, so how can we get them to remember the key things?

A
  • Give important information at the beginning and end of a consultation
  • Emphasise and repeat important information a few times
  • Make the information salient to the person (link to their problem specifically)
  • Chunk information into meaningful categories
  • Avoid overloading
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21
Q

What did Barlett’s ‘War of the Ghosts’ study show?

A

Study where student read a story and reproduced it to another person, with changed order, rationalisations and omissions

  • Majority of people think that memory accurately records events as we see and hear them
  • Most people don’t realise that it is susceptible to distortions
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22
Q

Can changing words when describing an event change someones perception of people’s memory?

A

Yes
• e.g. video showed to people of a car collision
• people asked how quickly the cars “hit” or “smashed” into each other
• When using the word “smashed”, they estimated a higher speed

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23
Q

What are 3 strategies that work in committing information to memory i.e. how to study?

A

1) Rote
• Frequent repetition
• Form a separate schema
• Least efficient

2) Assimilation into existing networks
• Learning by comprehension of meaning
• Fitting new information into existing schemas
• Can only be used where there is a link between old and new knowledge

3) Mnemonic device
• Artificial structure for reorganising or encoding information to make it easier to remember
• Useful when info doesn’t fit into existing schemas
• e.g. visual imagery, hierarchies, acronyms

24
Q

Give 4 examples of unknown causes of memory problems?

A
  • Vascular
  • Infectious
  • Toxic-metabolic
  • Autoimmune
25
Q

Can lesions in the pre-frontal cortex affect memory?

A

Yes

26
Q

What are the early features of Alzheimer’s disease?

A
  • Disorientation for time
  • Difficulty in finding way around familiar places
  • Anterograde and retrograde component
27
Q

What type of abilities are usually preserved till late in memory disorders?

A
  • Ability to perform over-learned skills e.g. driving, swimming, cooking etc.
  • Implicit memory - ability to learn a motor skill or react faster the second time
28
Q

How long does transient global amnesia last?

A

4-5 hours with complete recovery

29
Q

What is retrograde amnesia?

A
  • Loss of personal identity
  • Intact new learning is unusual
  • May be a psychiatric cause
  • Psychiatric history more likely to be present
  • Normal performance on memory test, but can suffer remote memory loss
  • Recovery may be sudden and triggered by emotional event
30
Q

What did the brain training study show?

A
  • Six-week online study, where participants were trained on cognitive tasks
  • Aim to improve reasoning, memory, planning, etc.
  • Improvements observed in every one of the cognitive tasks trained
  • No evidence for transfer effects to untrained tasks - even when cognitively closely related

Brain training makes you good at doing brain training tasks, but doesn’t generalise into other day-to-day cognitive abilities

31
Q

What is a phoneme?

A

The smallest unit of speech sound in a language that can signal a difference in meaning e.g. ø

32
Q

How many phonemes can humans produce, and how many are there in the English language?

A
  • Humans - 100 phonemes

* English - 44 phonemes

33
Q

What are morphemes?

A
  • The smallest units of meaning in a language
  • Typically consist of one syllable e.g. the
  • Morphemes are combined into words
34
Q

What is syntax?

A
  • Rules and principles, which govern the way in which morphemes and words can be combined to communicate meaning in a particular language
  • i.e. the arrangement of words to create well-formed sentences
35
Q

What is the Theory of Universal Grammar?

A
  • Under normal conditions, human beings will develop language with particular properties
  • A certain set of structural rules are innate to humans, independent of sensory experience
36
Q

At what age do babies tend to say their first recognisable words (as one-word utterances)?

A

12 months

37
Q

At what age do babies say their first rudimentary sentences, usually consisting of two words e.g. more milk?

A

12-18 months

38
Q

At what age will a child have learned the basic grammatical rules (combining nouns, adjectives etc. into meaningful sentences)?

A

4-5 years

39
Q

What is the critical period of language acquisition?

A
  • The first few years of life constitute the time during which language develops readily
  • After this period, language acquisition is much more difficult
40
Q

Is there a genetic contribution to language development?

A
  • Large genetic component to language development

* e.g. language problems associated with mutations of FOXP2 gene

41
Q

Which hemisphere is most language control lateralised to?

A

Left hemisphere

42
Q

What percentage of right-handed people have left-hemisphere dominance, and left-handed people have right-hemisphere dominance for language?

A
  • 95% of right-handed people have left-hemisphere dominance
  • 18.8% of left-handed people have right-hemisphere dominance

(shows dominance of left hemisphere)

43
Q

What is Broca’s aphasia and the symptoms of it?

A

Expressive issue
• Can understand speech but struggle to generate a response
• Non-fluent speech
• Impaired repetition
• High risk of depression - can’t get across what they want to say

44
Q

What is Wernicke’s aphasia and the symptoms of it?

A

Receptive issue
• Problem in comprehending speech
• Fluent meaningless speech - no problem with speaking
• Paraphasias - errors in producing specific words
• Neologisms - nonsense words
• Impairment in writing and reading - varies depending on site and extent of lesion

45
Q

What types of paraphasias can a Wernicke’s aphasia patient get?

A
  • Semantic paraphasias - substituting words similar in meaning e.g. barn instead of house
  • Phonemic paraphasias - substituting words similar in sound e.g. house instead of mouse
46
Q

What connects the language and speech areas of the brain?

A

Arcuate fasciculus

47
Q

Describe the passage of the signal from speech in the brain to be able to understand and reply to it?

A
  • Hear information
  • Auditory cortex processes it
  • Wernicke’s area tells you what that information means
  • Transmitted to Broca’s area via the arcuate fasciculus
  • From the Broca’s area, the person can decided how to respond
  • Broca’s area => motor cortex (controlling breathing and pharynx)
  • Speech is produced
48
Q

Is there just one connective tract relevant to language?

A
  • Modern findings show that there are many
  • e.g. uncinate fasciculus
  • Language function is widely distributed, far beyond Broca’s and Wernicke’s area
49
Q

What conditions are associated with aphasia?

A
Lesions to the dominant hemisphere can be caused by:
• stroke
• trauma
• cerebral tumour
• neurodegenerative conditions

Transient aphasia can be associated with:
• transient ischaemic attack (TIA)
• migraine

50
Q

What is dysexecutive syndrome?

A
  • Disruption of executive function
  • Encompasses cognitive, emotional and behavioural symptoms
  • Closely related to frontal lobe damage
  • Can result from many causes e.g. trauma, tumours, degenerative diseases and psychiatric conditions
51
Q

What are execute functioning skills?

A

Mental processes that enable us to plan, focus attention, remember instructions and juggle multiple tasks successfully

52
Q

Describe the 2 types of presentation of dysexecutive syndrome?

A
1.
• Hypoactivity
• Apathetic (lack of interest)
• Emotional bluntness
• Reduced empathy
2.
• Hyperactivity
• Impulsive
• Disinhibited
• Emotional dysregulation
• Socially inappropriate

Opposite presentations, but can co-occur at different times

53
Q

What cognitive difficulties do people with dysexecutive function have?

A
  • Attentional and working memory difficulties
  • Poor planning and organisation
  • Coping with novel situations
  • Switching from task to task
  • Keeping track of multiple tasks
  • Complex/abstract thinking
54
Q

What effects do deficits associated with the following regions of the frontal lobes have:
• Orbito-frontal
• Medial
• Lateral

A
  • Orbito-frontal - impulsivity
  • Medial - loss of spontaneity
  • Lateral - inability to formulate and carry out plans
55
Q

What is cerebellar cognitive affective syndrome?

A

People with lesions in the cerebellum may also have emotional, cognitive and behavioural changes, reflective of a frontal lesion

56
Q

Why might someone with a thalamic infarction appear to have a frontal lobe lesion?

A

The subcortical regions (includes the thalamus) sit posteriorly to the frontal lobe and are highly interconnected with it