10/7: Respiratory Pathology Flashcards
this is an area of airless pulmonary parenchyma due to collapse or incomplete expansion
atelectasis
what are the types of atelectasis?
resorption
compression
contraction
this is complete obstruction, mediastrium towards
resorption
this is fluid/air filling space preventing expansion, mediastium away
compression
what cells are found in hemodynamic edema?
hemodesrin-ladin macrophages (heart failure cells)
these diseases are characterized by an increase in resistance due to obstruction
obstructive lung disease
examples of obstructive disease
ephysema
chronic broncitis
asthma
bronchetitias
what makes up COPD?
emphsyema
chronic bronchitis
what groups are most susceptible for COPD?
women and AA
this is destruction of airway walls and enalrgement of airways distal to terminal bronchiole
emphysema
emphysema classification
centroacinar
panacinar
distal acinar
irregular
this emphysema is associated with alpha-1 trypsin deficiency
panacinar
what are the pathogensis of emphsema?
tabacco smoke
imbalance of proteases (elastase)
oxidative stress
describe alpha-1 deficiency
Pi on 14
homozygote = more likely for panacinar
you get not symptoms of emphysema until
1/3 lung affected
this is a chronic persistant cough
chronic bronchitis
what is asthma characterized by?
increased bronchoconstriction
increases mucus
atopic asmtha is what type of sensitivity
type 1 (IgE)
you see suptum and BAL speciemens that contain charcot-leyden crystals in what?
asthma
this is a recurring necrotizing infection that destorys smooth muscle and elastic tissue
bronchiectasis