10/7: Respiratory Pathology Flashcards

1
Q

this is an area of airless pulmonary parenchyma due to collapse or incomplete expansion

A

atelectasis

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2
Q

what are the types of atelectasis?

A

resorption
compression
contraction

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3
Q

this is complete obstruction, mediastrium towards

A

resorption

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4
Q

this is fluid/air filling space preventing expansion, mediastium away

A

compression

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5
Q

what cells are found in hemodynamic edema?

A

hemodesrin-ladin macrophages (heart failure cells)

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6
Q

these diseases are characterized by an increase in resistance due to obstruction

A

obstructive lung disease

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7
Q

examples of obstructive disease

A

ephysema
chronic broncitis
asthma
bronchetitias

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8
Q

what makes up COPD?

A

emphsyema
chronic bronchitis

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9
Q

what groups are most susceptible for COPD?

A

women and AA

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10
Q

this is destruction of airway walls and enalrgement of airways distal to terminal bronchiole

A

emphysema

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11
Q

emphysema classification

A

centroacinar
panacinar
distal acinar
irregular

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12
Q

this emphysema is associated with alpha-1 trypsin deficiency

A

panacinar

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13
Q

what are the pathogensis of emphsema?

A

tabacco smoke
imbalance of proteases (elastase)
oxidative stress

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14
Q

describe alpha-1 deficiency

A

Pi on 14
homozygote = more likely for panacinar

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15
Q

you get not symptoms of emphysema until

A

1/3 lung affected

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16
Q

this is a chronic persistant cough

A

chronic bronchitis

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17
Q

what is asthma characterized by?

A

increased bronchoconstriction
increases mucus

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18
Q

atopic asmtha is what type of sensitivity

A

type 1 (IgE)

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19
Q

you see suptum and BAL speciemens that contain charcot-leyden crystals in what?

A

asthma

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20
Q

this is a recurring necrotizing infection that destorys smooth muscle and elastic tissue

A

bronchiectasis

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21
Q

this is a lung disease in the setting of mineral dusts, particles, and chemical fumes

A

pneumoconioses

21
Q

what kind of diseases are restrictive?

A

pneumoconioses
silicosis
asbestos

22
Q

coeal worker’s lung disease (penumoconoisis) is characterized by what?

A

anthrocosis

23
Q

this pneumoconois is caused by inhaling crystalline silicone dioxide

A

silicosis

24
Q

what is the most common occupational disease worldwide?

A

silicosis

25
Q

this refers to a group of hydrate silicate crystals

A

asbestos

26
Q

what are the types of asbestos?

A

serpentine
amphibole

27
Q

this is a very common disease that causes 1/6s the deaths of the US

A

pulmonary infections

28
Q

this is the most common cause of community-acquired pneumoniae

A

streptococcus pneumoniae

29
Q

this is the most important cause of bacterial acute exacveration of COPD

A

haemophilus influenzae

30
Q

this is the most common gram negative bacteria pneumonia

A

Klebsiella pneumoniae

31
Q

this is found in water tanks, pipes

A

legionella pneumophilia

32
Q

consolidation occurs in what 2 patterns?

A

bronchopneumonia
lobar pneumonia

33
Q

what are the 4 stages of lobar pneumonia?

A

congestion
red hepatization
grey hepatization
resolution

34
Q

this consolidation occupes parts of lobe

A

bronchopneumonia

35
Q

this consolidation occupies the entire lobe

A

lobar pneumonia

36
Q

Sar-CoV-2 is transmitted through

A

respiratory droplets

37
Q

this is teh major cause of epidemics and pandemics

A

influenza virus

38
Q

Type ___ influenza infects human, swine, birds, and horses

A

A

39
Q

what is the characteristic of Primary tuberculosis?

A

Gohn Complex

40
Q

this type of pneumonia occurs in a debilitated patient with diminished swallowing reflex

A

aspiration pneumonia

41
Q

this type of pneumonia is when a patient is ill and on ventilator

A

hospital-acquire pneumonia

42
Q

what is the most common cause of cancer mortality world wide?

A

lung cancer

43
Q

this is caused by p53 mutations and tabacco smoking

A

SCC

44
Q

this has the strongest association with smoking and from neuroendocrine cells

A

small cell carcinoma

45
Q

this is similar to small cell carcinoma but without neuroendocrine cells

A

large cell carcinoma

46
Q

this is any type of lung cancer that may spread to pleural space

A

metastatic lung carcinoma

47
Q

what is the most common site of tumor metastasis

A

lung

48
Q

squamous papillomas are caused by

A

HPV 6 and 11

49
Q

how does laryngeal carcinoma work?

A

squamous hyperplasia –> dysplasia –> carcinoma