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Musculoskeletal > 1 Cartilage > Flashcards

1 Cartilage Flashcards

1
Q

What is cartilage

A

Specialized connective tissue,
Cells and macromolecules in ground substance,
Support, model for bone tissue

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2
Q

What does hematoxylin do

A

Basic stain
binds to acidic substances
Blue

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3
Q

What does eosin do

A

Red,
Binds to basic substances,
Binds to proteins

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4
Q

What role does cartaliage have in prenatal life

A 
Skeletal development (template),
Growth plates,
Synovial joints
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5
Q

Is cartilage Avascular or vascular

A

Avascular

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6
Q

Does cartilage regenerate well

A

No

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7
Q

What are the 2 cell types of cartilage

A

Chondroblasts

Chondrocytes

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8
Q

What is in the matrix

A

GAG,
proteoglycan,
fibers,
Water

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9
Q

Chondroblasts

A

Immature cartilage cells,
Secrete extracellular matrix,
Not in a lacuna

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10
Q

Chondrocytes

A

Mature cartilage cells

In lacunae

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11
Q

What makes up GAG’s

A

Chondroitin sulfate

Keratan sulfate

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12
Q

Main fiber for cartilage

A

Type 2 ?

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13
Q

What is the purpose of collagen fibers

A

Tensile strength and durability

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14
Q

What is hyaline cartilage

A

Most common
Type 2 collagen
Perichondrium except for the articular cartilage and epiphyseal growht plate

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15
Q

Appositional. Cartilage growth

A

Deposition of new cartilage matrix by Chondroblasts and perichondrial surface

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16
Q

Interstitial cartilage growth

A

Division of Chondrocytes within lacunae and synthesis of new cartilage matrix so that cartilage expands from within

17
Q

What is endochondral ossification

A

Cartilage template differentiates into bone

18
Q

Where is hyaline cartilage found in adults

A

Growth plates
trachea
Articular
Larynx

19
Q

Where is the epiphyseal growth plate located

A

Between epiphysis and diaphysis of long bone

20
Q

What is articular cartilage layers from outside to inside

A 
Tangential
Transitional 
Radial
Calcified
Bone
21
Q

What is a tidemark

A

Junction between radial zone and calcified cartilage

‘Joint surface’ in radiographs

22
Q

What kind of cartilage is articular cartilage

A

Hyaline

23
Q

Where is elastic cartilage found

A

External ear
Auditory tube
Epiglottis

24
Q

Does elastic cartilage calcify

A

No

25
Q

Where is fibrocartilage found

A

Intervertebral discs
Meniscus of stifle joint
Symphysis pubis
Insertions of tendons and ligaments

26
Q

What is fibrocartilage made of

A

Type one collagen fibers

27
Q

What are some key characteristics of fibrocartilage

A

No perichondrium
Irregular, dense, fibrous tissue
Resists compression and shear forces

28
Q

What forms the matrix

A

Proteolysis and fibrous proteins

Musculoskeletal (8 decks)

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