1 Cartilage Flashcards
What is cartilage
Specialized connective tissue,
Cells and macromolecules in ground substance,
Support, model for bone tissue
What does hematoxylin do
Basic stain
binds to acidic substances
Blue
What does eosin do
Red,
Binds to basic substances,
Binds to proteins
What role does cartaliage have in prenatal life
Skeletal development (template), Growth plates, Synovial joints
Is cartilage Avascular or vascular
Avascular
Does cartilage regenerate well
No
What are the 2 cell types of cartilage
Chondroblasts
Chondrocytes
What is in the matrix
GAG,
proteoglycan,
fibers,
Water
Chondroblasts
Immature cartilage cells,
Secrete extracellular matrix,
Not in a lacuna
Chondrocytes
Mature cartilage cells
In lacunae
What makes up GAG’s
Chondroitin sulfate
Keratan sulfate
Main fiber for cartilage
Type 2 ?
What is the purpose of collagen fibers
Tensile strength and durability
What is hyaline cartilage
Most common
Type 2 collagen
Perichondrium except for the articular cartilage and epiphyseal growht plate
Appositional. Cartilage growth
Deposition of new cartilage matrix by Chondroblasts and perichondrial surface
Interstitial cartilage growth
Division of Chondrocytes within lacunae and synthesis of new cartilage matrix so that cartilage expands from within
What is endochondral ossification
Cartilage template differentiates into bone
Where is hyaline cartilage found in adults
Growth plates
trachea
Articular
Larynx
Where is the epiphyseal growth plate located
Between epiphysis and diaphysis of long bone
What is articular cartilage layers from outside to inside
Tangential Transitional Radial Calcified Bone
What is a tidemark
Junction between radial zone and calcified cartilage
‘Joint surface’ in radiographs
What kind of cartilage is articular cartilage
Hyaline
Where is elastic cartilage found
External ear
Auditory tube
Epiglottis
Does elastic cartilage calcify
No
Where is fibrocartilage found
Intervertebral discs
Meniscus of stifle joint
Symphysis pubis
Insertions of tendons and ligaments
What is fibrocartilage made of
Type one collagen fibers
What are some key characteristics of fibrocartilage
No perichondrium
Irregular, dense, fibrous tissue
Resists compression and shear forces
What forms the matrix
Proteolysis and fibrous proteins
