1 Bolser Infrastructure of Skeletal Muscle Flashcards
Purpose of z bands
anchors thin filaments
Purpose of m line
anchors adjacent thick filaments
Characteristics of H band
only thick filaments
no overlap with thin filaments
What are z lines made of
A-actinin and z line filaments
What are M lines made of
Creatine kinase
What is in the space between myofibrils
SR
Mitochondria
Glycogen
Lipids
What is Titin
Protein that anchors M-bands
Purpose of Titin
imparts portion of passive elastic component on muscle
Help restore stretched sarcomere to correct length
What is dystrophin
Cytoskeletal protein located on inner surface of sarcolemma
What does dystrophin do
structural integity of sarcolemma
Anchor actin
Muscular dystrophy
No dystrophin
Affects all muscle
High creatine levels
What happens when you knockout myostatin
muscles on muscles on muscles
What happens when intracellular increases in Ca
Stimulate ATP driven pump on SR
How many Ca molecules are exchanged for an ATP molecule
2
Where are Ca pumps located
along longitudinal sarcotubules on SR
