1/19/17 Locally delivered Flashcards
What should precede subgingival irrigation?
-Scaling and Root planing
T/F
High irrigation forces should be utilized to avoid projecting bacteria into tissues.
False
Low irrigation forces protect the tissues
For locally delivered chemotherapeutics where must the drug reach to be effective?
-The base of the pocket
What are three things that make locally delivered chemotherapeutics effective?
- Reach the base of pocket
- Be in high concentrations to destroy bacteria
- Stick around long enough to be effective (7-10 days)
What are the advantages of locally delivered chemotherapeutics in the GCF?
-There are sustained higher drug concentrations found in the GCF
What is the golden standard of antibiotic locally delivered chemotherapeutics minocyclines?
-Arestin
What are three important characteristics of minocycline microsphere polymer?
- Bioadhesive
- Bioresorbable
- Proven Safety
What is the spectrum of Minocycline?
-Broad spectrum (Potent)
What is the action of minocycline?
-Bacteriostatic
T/F
The effect of minocycline microspheres with Scaling and root planing is incremental with the baseline depth of the pockets.
True
T/F
Minocycline Microsphere and scaling and root planing was not significantly more effective in reducing pocket depth than scaling and root planing alone.
False
-Was more effective
After a patient receives minocycline how long should they wait to brush their teeth?
-12 hours
Is Atridox a minocycline or doxycycline?
-Doxycycline
Which of the following drugs was said to not be used at all with women her are pregnant?
Atridox
Arestin
Atridox
Who are good candidates that you might use atridox in?
-Individuals with chronic adult periodontitis
