1/10/17 Systemic Antibiotics Flashcards
What two things are essential for periodontal disease to develop?
- Microbial plaque
- Susceptible host
What are the clinical benefits of chemotherapeutic agent?
- Antimicrobial actions
- Ability to increase the hosts resistance
What are the three major categories of chemotherapeutics in periodontal treatment management?
- Systemic antibiotics
- Controlled drug delivery systems
- Drugs that modulate host response
T/F
There is no evidence that antibiotics alone can arrest periodontal disease
True
Should you give antibiotics to diabetic patients to help treat periodontal disease?
-Yes if they are uncontrolled If controlled treat them like they don’t have diabetes
What type of periodontitis can and should be treated initially without systemic antibiotics?
-Chronic periodontitis
What type of periodontitis are antibiotics used to treat?
-Aggressive Periodontitis
What is the initial therapy for chronic periodontitis?
-Scaling and Root planing
Antibiotics used in periodontal therapy are selected based on the what three things?
- Microbial composition of the plaque
- Patients medical status
- Current medications
When taking a microbial sample what type of fluid do you place the sample in?
-RTF (Reduced Transport Fluid)
Periodontal disease is predominately what type of bacteria?
Gram +
Gram -
-Gram negative anaerobic
T/F
Antibiotics should be used as a monotherapy in periodontal therapy
False
It should not be used as a monotherapy but should be part of a comprehensive treatment plan
When considering the use of antibiotics during periodontal therapy other than patients with aggressive periodontitis what other individuals should be considered?
- Heavy Smokers
- Immunocomporomised
- Conjunction with some surgical procedures
- Refractory periodontitis (High risk patients)
- Necrotizing ulcerative periodontal disease
T/F
Penicillin is a commonly used antibiotics in periodontal therapy
True
What is the mechanism of action of penicillins?
-Inhibit cell wall synthesis
What is the spectrum of penicillins?
-Narrow
What is the effect of penicillins?
-Bacteriocidal
What are three frequently used penicillins (PCNs) used in periodontal therapy?
- Amoxicillin
- Pen VK
- Amoxicillin with clavulanic acid (Augmentin)
T/F
Tetracyclines are a commonly used antibiotic in periodontal therapy
True
What is the mechanism of action of tetracyclines?
-Inhibit protein synthesis
What is the spectrum of tetracyclines?
-Broad spectrum
What is the effect of tetracyclines?
-Bacteriostatic
What is an advantage of using tetracyclines?
- Concentrates in the tissues
- Destroys A.a.
- Anticollagenase activity
T/F
Tetracyclines increase photosensitivity in people
True
