09 - Bordetella

Question 1

(Bordetella)

1. gram?
2. shape?
3. oxygen use?
4. motile?
5. hemolytic?
6. Commensals of where?
7. Causes what disease in mammals and birds?

Answer 1

1. negative
2. pleomorphic coccobacilli
3. aerobic - obligate, not able to survive for long periods outside hosts
4. either
5. most are (not avian)
6. upper respiratory tract
7. respriatory disease

Question 2

(Bordetella)

1. eight species
2. all produce what?
3. Have tropism for what?

Answer 2

2. acute or chronic respiratory disease (in various animals, humans, birds)
3. ciliated epithelium

Question 3

Answer 3

Question 4

(Bordetella Toxins)

There are four toxins produced by Bordetella that play a role in important diseases

1-4. What are they?

Answer 4

1. dermonecrotic toxin
2. tracheal cytotoxin
3. LPS (endotoxin)
4. Adenylate cyclase

Question 5

(Bordetella Toxins)

(1. Dermonecrotic Toxin)
1. heat labile toxin
2. funcitonally the same as that of P. multocida?
3. smoot muscle of peripheral blood vessels, arterial constriction, ischemia
4. toxin is intracellular, released when?

Answer 5

2. no
3. upon lysis of bacteria

Question 6

(Bordetella toxins)

(2. Tracheal cytotoxin)
1. exhibits trophism for what?
2. causes what?
3. This toxin is released, thus is a what?

Answer 6

1. for ciliated resp epithelium
2. destruction of ciliated cells
3. cytotoxin

Question 7

(Bordetella Toxins)

(3. Endotoxin)
1. fever, complement activation
(4. Adenylate Cyclase - except B. Avium)
2. inhibits what and what?
3. how does it work?

Answer 7

2. phagocytosis and phagosome-lysosome fusion
3. look at pic

Question 8

(Bordetella Pertusssis)

1. motile?
2. Natural host in what?

Answer 8

1. no
2. humans

Question 9

(Bordetella Pertussis)

Question 10

(Bordetella Pertussis)

1. Transmitted by what?
2. What is used as a vaccine?
3. even with vaccines, whooping cough still common in US
4. treatment?

Answer 10

1. aerosol droplets
2. KILLED toxin (protection lasts a few years)
3. erythromicin

Question 11

(Bordetella parapertussis)

1. more or less severe than whopping cough?
2. Recently isolated in what?

Answer 11

1. less
2. sheep (similar to bordetella pertussis)

Question 12

(Bordetella bronchiseptica)

1. aerboic, bipolar
2. motile - peritrichous flagella

3 (pos or neg?) urease, oxidase, catalase?

4. alkalinizes what?
5. What required for primary isolation?

Answer 12

3. pos to all
4. litmus milk
5. blood or serum

Question 13

(Bordetella bronchiseptica)

1. Causes what in swine?
2. In dogs?

3.

Answer 13

1. atrophic rhinitis (sometimes w. P. multocida)
2. kennel cough (borderlla is most common cause of tracheobronchitis in dogs

Question 14

(What is Kennel Cough?)

Answer 14

Question 15

Answer 15

Question 16

Answer 16

PAY ATTENTION TO THIS SLIDE

Question 17

(Bordetella bronchiseptica)

Answer 17

Question 18

Answer 18

Question 19

Question 20

(Bordetella Avium)

1. B. avium resembles B. bronchiseptica in its growth and culutral characteisisc
2. How is it different?

Answer 20

2. doesn’t produce urease

Question 21

(Bordetella Avium)

1. highly contagious upper respiratory tract disease of what?
2. morbidity? mortality?
3. causes what?
4. aka?
5. Infection is spread how?

Answer 21

1. poults
2. high, low
3. rhinotrachetis
4. TURKEY CORYZA
5. direct contact, by aerosols and environmental sources

Question 22

(Bordetella Avium)

1.

Answer 22

Question 23

Answer 23

Question 24

Question 25

(Bordetella)

(susceptible to…)

1. disinfectants
2. broad-spec antibiotics
3. polymixin
4. penicillin

Answer 25

1-3. yes

4. no