(08) Digestive System III Flashcards
Name the Eight Cell types in gastric glands
Madison Garden Pec Gum
- Mucous (neck) cells
- Gastric Surface mucous cells
- parietal cells
- enteroendocrine
- chief, zymogen or peptic cells
- goblet cells
- undifferentiated (cuboidal) cells
- mucous cells of glands
(Simple Stomach Continued)
(Cell Types in Gastric Glands)
(Mucous neck Cells)
- predominant cell type in what glands?
- Low columnar or cuboidal cells often with what shaped nucleues?
- In fundic gland, found only where?
- Is cytoplasm more or less basophilic than surface epithelial cells?
- pyloric and cardiac
- flattened or crescent-shaped nucleus
- in neck of the gland = mucous neck cells
- more basophilic
(Simple Stomach Continued)
(Cell Types in Gastric Glands)
(Gastric surface mucous cells)
- columnar cells in a “sheet” which covers the luminal surface of …. cuts off here….
- are the basal nuclei flattened?
- Secrete what?
- secretes what, which neutralizes H+ before it can diffuse through … cuts off here….
- -
- no
- mucins
- HCO3-
(Simple Stomach Continued)
(Cell Types in Gastric Glands)
(Parietal Cells)
- Primarily found in what type of glands?
- size? shape? acidophilic or basophilic?
- Tend to bulge to where?
- Many or few mitochondria?
- Have what with microvilli to increase membrane surface area for secretion?
- fundic glands
- large, pyramidal, acidophilic
- periphery of gland
- many
- intracellular canaliculus
(Simple Stomach Continued)
(Cell Types in Gastric Glands)
(Parietal Cells Continued)
- inactive cells internalize membranes of the microvilli to form what?
- Produce stomach acidity by pumping what and what into the lumen?
- secrete what?
- tubulovesicular membranes
- H and Cl (forms HCl)
- intrinsic factor
(Simple Stomach Continued)
(Cell Types in Gastric Glands)
(Chief, Zymogen or peptic cells)
- Are found where (where they are the most numerous cell type)?
- Columnar with pale basophilic staining basal cytoplasm
- Cell apices are filled with zymogen granules containing what two things?
- EM structure is that of a typical what?
- Secrete what in young animals?
- Fixation may leach out the zymogen and leave the cells appearing empty or foamy.
- fundic glands
- pepsinogen (and also gastric lipase)
- protein secreting cell
- rennin (curdles milk)
(Simple Stomach Continued)
(Cell Types in Gastric Glands)
(Enterendocrine cells)
- part of what system?
- Occur sparsley throughout what?
- Occur singly, adjacent to what?
- Does the apex of cell reach the gland lumen?
- APUD (Amine Precursor uptake and decarboxylation)
- stomach and intestine
- basal lamina
- it may not
(Simple Stomach Continued)
(Cell Types in Gastric Glands)
(Enterendocrine cells cont)
- APUD cells secrete mostly into what? Where hormones diffuse to what or what?
- Cells are located singly throughout what?
- How many types of enteroendocrine cells have been identified?
- Secretions are important for coordination and control of what?
- Single cells are located in the surface or glandular epithelium adjacent to what and may not reach what?
- Contain basal, membrane bound granules
- a cell may secrete more than one type of hormone
- the interstitium; blood vessels or nearby target cells (part of the gastroenteropancreatic system of endocrine cells)
- gastric and intestinal epithelium
- more than 30
- GI function (secretion and motility)
- basal lamina; gut lumen
(Simple Stomach Continued)
(Examples of Enteroendocrine cells)
- These secrete serotonin and are found throughout the GI tract
- These secrete enteroglucagon
- these secrete insulin
- thse secrete somatostatin (pancreas)
(Cell Types in Gastric Glands)
- Argentaffin cells
- pancreatic alpha cells
- beta cells
- D-cells
(Simple Stomach Continued)
(Cell Types in Gastric Glands)
(Undifferentiated (cuboidal) cells in neck region)
- Give rise to what?
- Mucous cells differ in what?
- ? = glycoproteins, the cheif constituent of mucus
- ? = the free “slime” of mucous membranes including secretions of the mucous glands
- all cells of the gastric gland
- type of mucin produced
- mucin
- mucus
(Simple Stomach Continued)
(Cell Types in Gastric Glands)
(Mucous cells of glands)
- what shape?
- What shape basal nuclei?
- predominant cell type in what glands?
- in fundic gland region - what are they?
- low columnar
- flattened or cresent-shaped
- cardiac and pyloric
- mucous neck cells
(Simple Stomach Continued)
(Cell Types in Gastric Glands)
(Goblet cells)
- occur singly or in small clusters throughout what?
- narrow base, flared apex
- what shape basal nuclei?
- also in what and what?
- intestine
- flattened
- respiratory system and some large ducts
and then read the rest - sorrs