06 - Coccidia Flashcards

(Apicomplexa)
- parasitic?
- Do they have locomotory organelles?
- apical complex - observed in what?
- yes - they all are
- no (except for flagellated microgametes - similar in function as sperm)
- “zoites”

(Stages)
(-zoite)
- shaped like what?
- occurs in what forms?
- typically what?
(-ont)
- many forms… what two?
- motile?
(gametocytes)
- structures with products (-gametes) of what?
- banana
- merozoite, sporozoite, tachyzoite, badyzoite
- motile, active form
- meront, schizont
- usually non
- gamete formation (gametogony)
(Family: Eimeriidae - coccidia)
- they are monoxenous… what does this mean?
- What are the two major genera?
- Life cycle has three stages… what are they?
- have one host
- Eimeria and Isospora
- schizogony (merogony)
gametogony
sporogony

(Family: Eimeriidae - coccidia)
- What kind of reprduction within the host?
(mutliple fission - schizogony or merogony)
- repeated nuclear division before what?
- dividing cell called a what?
- subunits are called what?
(Gametogany and Syngamy)
- formation and fusion of male and female gameters to form a what?
- asexual and sexual reproduction
- cytokinesis
- schizont (or meront)
- merozoites
- zygote (–> oocyst)
(Family: Eimeriidae - coccidia)
(Sporogony - Oocyst)
- product of what?
- transmissible?
- sporulates (sporogony) outside host to do what?
(eimeria)
- what is this?
(Isospora)
- what is this?
- sexual reproduction (gametogony)
- transmissible form between hosts
- to become infective
- 4 sporocysts each with 2 sporozoites
- 2 sporocysts each with 4 sporozoites



(Family: Eimeriidae - coccidia)
(Eimeria)
- tend to be very host specific
- for what?
(Isospora (Cystoisospora))
- host specificity?
- for what?
- herbivores
- less
- carnivores (exception = swine)

(Coccidia Life Cycle)
- ingestion of what?
- what are released?
- enter what?
- an infective (sporulated) oocyst
- sporozoites
- and epithelial cell

(Coccidia - typical life cycle - cont)
- BEcomes a what?
- what generation?
- what develops?
(then. ..) - schizont bursts and what are released?
- what happens to first generation merozoites?
- schizont (schizogeny)
- first
- merozoites
- merozoites
- enter another eipithelial cell

(Coccidia - typical life cycle - cont)
- usually how many generations of schizon’ts/merozoites?
- 2-3



(Coccidia - Typical Life Cycle)
- The 2nd or 3rd generation merozoite enters what?
- Develops into what?
- what forms… that develops into an oocyst?
- another epithelial cell
- a micro- or macrogametocyte (male and female gamonts)
Gametogony
microgametes (escape from microgametocyte, fertilize the macrogametocyte)
- a zygote


(Coccidia - Typical Life Cycle)
- Oocyst ruptures cells and does what?
- oocyst undergoes what outside the host?
(sporulation)
- 4 - 2’s = ?
- 2 - 4’s = ?
- After sporulation the oocyst is infective?
- passes out in feces
- sporogony
- Eimeria
- Isospora
- infective



(Coccidia)
- What is coccidiasis?
- coccidiosis?
- presence of coccidian parasites
- presence of coccidian parasites and the resulting clinical signs

(Epidemiology)
(Dispersion)
humans, wind, birds etc.


(Coccidia of Domestic Poultry)
- All belong to what genus?
- Eimeria

(life Cycle of Eimeria Tenella)
- oocyst passed in feces
- With adequate moisture and temperature: get what?
- Oocyst may remain inactive for how long?
- Infection is by what?
- oocyst sporogony –> 24-48 hours
- 2-3 months
- ingestion of oocyst
(Life Cycle of Eimeria Tenella cont)
- After ingestion, sporozoites are released and do what?
- become what?
- F1 merozoites invade another cell and form what?

- penetrate cecal epithelial cells
- schizonts (schizogony –> 900 merozoites in 3 days)
- F2 schizonts (–> 200-350 merzoites by 5 days)
(Life Cycle of Eimeria Tenella)
- Many F2 merozoites enter a new host cell and begin what?
- most become what?
- Some bcome what?
- the sexual phase (gametogony)
(others may go thorugh another schizogony)
- macrogametocytes
- microgametocytes (which develop numerous microgametes)
(Lfe Cycle of Eimeria Tenella cont)
(microgametes)
- flagellated… do what?
(Zygote)
- does what?
- Oocysts enter cecal lumen and do what?
(prepatent period (PPP) ~7d)
- interval between what?
- fertilize the macrogamete
- lays down a thick wall and breaks out of host cell
- pass out with feces/diarrhea
- ingestion and first appearaonce of oocysts in feces
(Life Cycle of Eimeria Tenella)
- a single oocyst has the potential to produce how many F2 schizonts?
- Most bcome macrogametes –> ?
- 2,520,000
- oocysts
(Eimeria Tenella)
- Most pathogenic of what?
- Estimated losses are over 40 mil ww - plus anti-coccidial compounds
- found most often in birds of what age?
- chicken coccidia
- 4 weeks of ages (cecal coccidosis)
(eimeria tenella)
(pathogenesis)
- may vary in severity from inapparent to acute (fatal, depends on what?
- Also impacted by breed, age, nutritional status and stress factors
- size of infecting dose


(eimeria tenella)
(pathogenesis/clinical signs)
- loss of blood may lead to what?
- recovery is slow (if they do)
- older birds can do what?
- anemia
- dvelop immunity
(Eimeria Necatrix)
(life cycle)
- common worldwide
- 1st and 2nd generation schizonts are wher?
- 3rd gen schizonts and gametogony occur where?
- small intestine
- ceca
(Eimeria Necatrix)
(pathogogenesis)
- what gen is most pathogenic?
- thought to cause more chronic disease due to what?
- pathology primarily where?
- lesions are what in appearance?
- death occurs 5-7 days pi
- 2nd
- extensive scarring of the si
- middle third of the si
- small and white




(Eimeria Adenoides)
- common, found worldwide
- PPP = ?
- parent period = ?
- Most of the life cycle takes place where?
- 4-6 days
- 7-20 days
- the lower 1/3 of the si, ceca, and rectum
(Eimeria adenoides)
(pathogenesis)
