05 - Leishmania Flashcards
1
Q
(Leishmania)
- What form in vertebrates?
- live where?
A
- amastigote
- inside macrophages, within phagolysosoms
2
Q
(Leishmania)
(Hosts)
- are what?
- vectors?
A
- vertebrates (mammals primarily)
- sand flies
3
Q
A
4
Q
A
5
Q
(L. Infantum)
- Had only been observed where?
- Zoonotic viesceral leishmaniasis
what are the natural reservoir host?
(Canine visceral leishmaniasis)
- dogs also get sick
- involvement of what?
A
- the old world (Asia, Middle east, southern europe, NW Africa
- dogs
- visceral and cutaneous involvement
6
Q
A
7
Q
A
8
Q
L. Infantum
Transmission
- has to fit foxhound only pattern
- what is transmission?
A
- direct dog-to-dog transmission
biting, reusing needles for injections, blood transfusions, breeding (transplacental transmission)
9
Q
L. Infantum
Transmission
(Sandflies)
- Some N American Sandfy species have become infected after doing what?
(But are they competent vectors?)
- well?
A
- feeding on L. infantum-infected dogs
- if canine reservoir becomes larger and more dispersed, the possibility of vector-borne transmission will increase (zoonotic risk)
10
Q
(L. infantum in foxhounds)
- What kind of infection?
A
- autochthonous infection