05 - Leishmania Flashcards

1
Q

(Leishmania)

  1. What form in vertebrates?
  2. live where?
A
  1. amastigote
  2. inside macrophages, within phagolysosoms
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2
Q

(Leishmania)

(Hosts)

  1. are what?
  2. vectors?
A
  1. vertebrates (mammals primarily)
  2. sand flies
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3
Q
A
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4
Q
A
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5
Q

(L. Infantum)

  1. Had only been observed where?
  2. Zoonotic viesceral leishmaniasis

what are the natural reservoir host?

(Canine visceral leishmaniasis)

  1. dogs also get sick
  2. involvement of what?
A
  1. the old world (Asia, Middle east, southern europe, NW Africa
  2. dogs
  3. visceral and cutaneous involvement
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6
Q
A
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7
Q
A
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8
Q

L. Infantum

Transmission

  1. has to fit foxhound only pattern
  2. what is transmission?
A
  1. direct dog-to-dog transmission

biting, reusing needles for injections, blood transfusions, breeding (transplacental transmission)

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9
Q

L. Infantum

Transmission

(Sandflies)

  1. Some N American Sandfy species have become infected after doing what?

(But are they competent vectors?)

  1. well?
A
  1. feeding on L. infantum-infected dogs
  2. if canine reservoir becomes larger and more dispersed, the possibility of vector-borne transmission will increase (zoonotic risk)
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10
Q

(L. infantum in foxhounds)

  1. What kind of infection?
A
  1. autochthonous infection
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