06 - CBC

Question 1

3 main causes of decreased RBC

Answer 1

1. hemolysis
2. blood loss
3. decreased production

Question 2

3 causes of RBC hemolysis

Answer 2

1. IMHA
2. infectious
3. zinc

Question 3

5 causes of infectiuos causes of decreased RBC

Answer 3

1. mycoplasma
2. rickettsial
3. babesiosis
4. cytauxzoonosis
5. heartworm

Question 4

4 causes of decreased RBC due to decreased production

Answer 4

1. anemia of chronic inflammatory disease
2. decreased EPO (renal dz, hypothyroid, Addisons)
3. infectious (FeLV, FIV, rickettsial)
4. bone marrow dz (neoplasia, myelofibrosis, etc)

Question 5

2 causes of increased red blood cells

Answer 5

1. relative increase (dehydration, splenic contraction)
2. physiologic increase (chronic lung disease, chronic cardiac disease)

Question 6

Two causes of decreased MCV

Answer 6

1. iron deficiency
2. liver disease (PSS, liver failure)

Question 7

two causes of increased MCV

Answer 7

1. regenerative anemia
2. felv infection

Question 8

two causes of decreased MCH

Answer 8

1. reticulocytosis
2. iron deficiency (decreased hemoglobin production)

Question 9

6 causes of normal reticulocytes in anemic patient

Answer 9

1. chronic inflammatory disease
2. lack of EPO (chronic renal disease, hypothyroid, addison’s)
3. infectious (FeLV, FIV, rickettsial)
4. liver disease/PSS
5. iron def
6. chronic blood loss

Question 10

2 causes of increased reticulocytes in anemic patient

Answer 10

1. blood loss (trauma, parasites, ruptured neoplasms, etc)
2. hemolytic disease (IMHA, infectious, zinc)

Question 11

3 main causes of decreased neutrophils

Answer 11

1. decreased marrow production
2. increased tissue demand (sepsis, viral, abscess)
3. toxicity (estrogens, chemo)

Question 12

two main causes of decreased neutrophils due to decreased bone marrow production

Answer 12

1. infection (parvo, FeLV, toxo, rickettsial)
2. neoplasia

Question 13

2 causes of increased neutrophils

Answer 13

1. inflammatory response (infectious, immune mediated, necrosis, neoplasia)
2. steroid induced

Question 14

What causes increased bands in neutrophils?

Answer 14

inflammatory response

Question 15

4 Causes of decreased lymphocytes

Answer 15

1. corticosteroid induced
2. acute systemic inflammation (infection, endotoxemia)
3. lymphangiectasia, PLE, GI lymphoma
4. chylous effusion

Question 16

4 Causes of increased lymphocytes

Answer 16

1. epinephrine
2. chronic antigenic stimulation
3. addison’s
4. lymphocytic neoplasia

Question 17

1 cause of decreased monocytes

Answer 17

bone marrow disease

(can be a normal finding)

Question 18

2 causes of increased monocytes

Answer 18

1. inflammatory response
2. steroid induced

Question 19

1 cause of decreased eosinophils

Answer 19

1. steroid induced

can be normal

Question 20

2 causes of increased eosinophils

Answer 20

1. parasitic infection
2. allergic/hypersensitivity reaction

Question 21

6 causes of increased eosinophils due to allergic/hypersensitivity

Answer 21

1. asthma
2. eosinophilic granuloma complex
3. allergic dermatitis/atopy
4. food allergies
5. eosinophilic gastroenteritis
6. allergic rhinitis/sinusitis

Question 22

3 caues of increased nucleated RBC

Answer 22

1. regenerative anemia
2. splenic disease
3. post-splenectomy

Question 23

3 causes of decreased platelets

Answer 23

1. artifact (clumping)
2. decreased production (bone marrow suppression)
3. consumption/destruction

immune mediated (severe)

non-immune (blood loss, DIC, local intravascular coagulation) (mild to moderate)