05 - Criteria of Malignancy

Question 1

(criteria of malignancy)

1. do cellular or nuclear/nucleolar carry more weight?

Answer 1

1. nuclear/nucleolar

Question 2

(criteria of malignancy: nuclear)

1. name the 5 things

Answer 2

1. size (anisokaryosis)
2. shape (pleomorphism)
3. multiple nuclei (odd esp bad)
4. coarse/atypical chromatin pattern
5. nuclear molding (deformation of one nucleus by another nucleus or cell pressing against it)

Question 3

(criteria of malignancy: nucleolar)

1-3. what 3 things?

Answer 3

1. multiplicity
2. pleomorphism
3. variable size

Question 4

(criteria of malignancy: cellular)

1-6. what 6 things?

Answer 4

1. shape (pleomorphism)
2. variable size (pleomorphism)
3. abnormal granules/vacuoles
4. number/how easily exfoliated
5. mitotic figures
6. N:C ratio (esp high)

Question 5

mitotic figure = ?

Answer 5

a cell undergoing mitosis