02.18a Surgical Management of CAD Flashcards
Etiology of CAD
Atherosclerosis
Risk factors of CAD
Age Cigarette smoking HPN Dyslipidemia Sedentary lifestyle Obesity DM
How to prevent CAD according to Class 1 recommendations by the ACC and AHA
Smoking cessation BP < 140/90 (130/80 for DM or CKD) LDL < 100 ASA therapy BMI < 25 DM management HbA1c < 7% Daily exercises
Clinical manifestations of CAD
Angina pectoris MI Ischemic heart failure Arrhythmia Sudden death
Clinical evaluation of CAD
Lab work-up Chext x-ray 12-lead ECG Stress test (Stress Echocardiography) 2D echocardiography Coronary angiography
Have the ability to assess global ventricular function in terms of LV ejection fraction which can be used to determine operative risk
Stress echocardiography
Primary diagnostic tool for CAD
Coronary angiography
Normal LV ejection fraction
0.55-0.70
Mild depression level of LV ejection fraction
9
Moderate level of LV ejection fraction
< 0.4
Severe level of LV ejection fraction
< 0.25
Evidence and or general agreement that procedure is beneficial, useful and effective
Class I
Conflicting evidence
Class II
Conflicting evidence in favor of usefulness or efficacy
Class IIA
Conflicting evidence in favor of not being useful
Class IIB
Evidence and or general agreement that procedure is not useful or effective and may be harmful
Class III
Significantly higher rates of repeat revascularization in _____
PCI than CABG
Most important criterion in conduit selection
Graft patency
Conduit with highest patency rate
Internal thoracic artery
Vessels used for conduit
Internal mammary artery
Saphenous vein graft
Radial artery
Gastroepiploic artery
How to harvest saphenous vein
Conventional vein harvesting
Endoscpic vein harvesting
Open technique, incision is made along the course of the vein on the medial aspect of the lower extremity
Conventional vein harvesting
Starts with a small incision just above and medial to the knee where the endoscope is inserted
Endoscopic vein harvesting
In using radial artery, confirm ulnar collateral flow to the hand by
Allen’s test
Duplex ultrasound study
In harvesting radial artery, incision is made point near the _____
radial styloid process ending just medial and distal to the biceps tendon on the non-dominant hand
To preserve myocardium, a temperature of ____ is needed
28 - 33 dec C
Types of cardioplegic solution
Crystalloid
Blood
Recommended to revascularize the area with the most concern for ischemia then give cardioplegia down the completed graft
Retrograde cardioplegia
In LAD graft, this is performed last to avoid kinking or disruption of bypass
Left internal thoracic artery
Does not make use of the heart-lung machine
Done to avoid the adverse consequences of cardiopulmonary bypass
Heart is left beating through myocadial stabilization devices for immobility while anastomoses are being done
Off-pump coronary artery bypass (OBCAP)
One internal mammary and the rest are veins
Single IMA CABG
Arteries still come from internal mammary artery
Higher success rates
Bilateral IMA CBG
Fats in the vein are left behind and grafted
No touch saphenous vein technique
Saphenous vein solution
Nitric oxide synthase
Minimal incision, but maximum difficulty
Done through a left anterior mini-thoracotomy through which mobilization of the left internal thoracic and direct anastomosis to LAD is performed
Done to single-vessel disease
Minimally invasive direct coronary artery bypass (MIDCAB)
Surgery may perform the procedure from another place, through the use of consoles
Expensive
Total endoscopic coronary artery bypass (TECAB)
Similar to catheterization lab but it also serves as an operating room
Provides catheterization, agiography, CABG
Hybrid coronary revascularization
Puncture the myocardium and expose to laser
Candidates are those not allowed for stenting, angioplasty or bypass
Transmyocardial laser revascularization
Used for patients with end stage coronary artery disease
No longer recommended
Transmyocardial laser revascularization
Regenerative medicine and tissue engineering
Cardiac stem cell theray
Alternatives to CABG
Off-pump coronary artery bypass
Multiple arterial coronary revascularization
Minimally invasive direct coronary artery bypass
Total endoscopic coronary artery bypass
Hybrid coronary revascularization
Transmyocardial laser revascularization
Cardiac stemm cell therapy