02.1 The HPG Axis Flashcards
Which part of the pituitary gland is under neural control?
Posterior
Which part of the pituitary gland is under hormonal control?
Anterior
What hormones does the posterior pituitary gland secrete?
ADH
Oxytocin
What hormones does the anterior pituitary gland secrete?
Prolactin Growth Hormone TSH ACTH FSH LH
Which hormone stimulates the anterior pituitary to secrete FSH/LH?
GnRH
Where do LH and FSH act?
Gonads
Where is inhibin secreted from?
Gonads
What does inhibin negatively feedback on?
FSH Secretion specifically
What does testosterone negatively feedback on?
GnRH
How do moderate amounts of oestrogen feedback?
Negatively on GnRH
How do high levels of eostrogen alone feedback?
Positively on GnRH (LH Surge)
How does progesterone affect oestrogen feedback?
It prevents GnRH secretion
In females, which cells secrete inhibin?
Granulosa cells
In females, which cells secrete oestrogen?
Theca interna
In males, where does LH and FSH act respectively?
Leydig cells, Sertoli cells