02.1 The HPG Axis Flashcards

1
Q

Which part of the pituitary gland is under neural control?

A

Posterior

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2
Q

Which part of the pituitary gland is under hormonal control?

A

Anterior

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3
Q

What hormones does the posterior pituitary gland secrete?

A

ADH

Oxytocin

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4
Q

What hormones does the anterior pituitary gland secrete?

A
Prolactin
Growth Hormone
TSH
ACTH
FSH
LH
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5
Q

Which hormone stimulates the anterior pituitary to secrete FSH/LH?

A

GnRH

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6
Q

Where do LH and FSH act?

A

Gonads

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7
Q

Where is inhibin secreted from?

A

Gonads

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8
Q

What does inhibin negatively feedback on?

A

FSH Secretion specifically

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9
Q

What does testosterone negatively feedback on?

A

GnRH

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10
Q

How do moderate amounts of oestrogen feedback?

A

Negatively on GnRH

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11
Q

How do high levels of eostrogen alone feedback?

A

Positively on GnRH (LH Surge)

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12
Q

How does progesterone affect oestrogen feedback?

A

It prevents GnRH secretion

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13
Q

In females, which cells secrete inhibin?

A

Granulosa cells

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14
Q

In females, which cells secrete oestrogen?

A

Theca interna

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15
Q

In males, where does LH and FSH act respectively?

A

Leydig cells, Sertoli cells

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16
Q

Which cells secrete inhibin and what hormone is this in response to?

A

Sertoli cells/granulosa cells in response to FSH