(02-03) Allergic Skin Diseases: Atopic Dermatitis: Gods Flashcards
atopy is defined as what?
Atopic dermatitis is what?
atopic dermatitis is thought to be mainly a true what?
inherited predisposition to develop IgE antibodies to environmental allergens, which are normally innocuous substances
when cutaneous signs result
type I hypersensitivty reaction (IgE mediated)
(IF)
1. Atopic dermatitis is an inherited predisposition for what?
- how do sensitizing agents get in?
- what are allergens commonly involved in canine atopic dermatitis?
- development of IgE antibodies to innocuous environmental allergens, which will result in cutaneous signs
- inhaled/penetrate skin
- pollens and house dust
(IF)
- What is the single most important in the diagnosis and treament of canine atopy?
- the historical hallmark of canine atopic dermatits is what?
- Signs usually start at what age?
- clinical signs are seasonal or non?
- Because of the genetic predisposition, the disorder is recognized more frequently in certain breeds or families
- thorough history
- pruritis
- 1 to 3 years (can be from 6 months to 6 years)
- can be either
(IF)
- pruritis is typically located to what?
- what is common in dogs with atopic dermatitis?
- How often will atopic dermatitis be associated with primary lesions? any lesions are what?
- How common are secondary staph pyoderma, seborrhea, Malassezia dermatitis in atopic dogs?
- face, axillae, ventrum, lateral thorax, and feet
- otitis externa
- rarely; secondary to scratching or complicating diseases (pyoderma, seborrhea, malassezia dermatitis)
- VERY common (often aggravate pruritis primarily related with atophy)
(IF)
- atopic dermatitis can mimic what?
- sarcoptic mites are only in what percentage of cases?
- Do what if you suspect of sarcoptic mange and mites were not found on multiple skin scrapings
- sarcoptic mange
- 50% of cases
- perform a treatment trial
(IF)
- Is there a perfect test for diagnosing atopic dermatitis?
- what are other causes of pruritic dermatitis that can appear similar to atophy that should be ruled out?
- no
2. food allergy, contact allergy, sarcoptic mange, cheyletiellosis, flea allergy, and pruritic pyoderma
(IF)
1. Treat every case as a single patient
2. can atopy be cured?
3. what three things often aggravate pruritis associated with atopy?
4. Response to hyposensitization vaccine therapy using a recipe from a serum allergy test (RAST
or ELISA) is less or more (50% response) compared to the response using a vaccine recipe based on a
skin test?
5. In general, results are not observed before when?
- no - only controlled with therapy
- staph pyoderma, malassezia dermatitis, and seborrhea
- less (70%)
- 3 months of therapy (and may not be noted until 9 to 12 months)
(IF)
- Medical therapy should be instituted when?
- Medical therapy includes antihistamines, fatty acid supplements, corticosteroids, other immunomodulating drugs and medicated shampoos and conditioners.
- Always do an antihistamine trial to determine what?
- Antihistamines and essential fatty acids work how?
- Treat what before considering the use of corticosteroids?
- if the animal is not a candidate for hyposensitization therapy, when waiting for the hyposensitization to work, or if the animal does not respond to hyposensitization therapy.
- the best one to be used as maintenance
therapy. - synergisticaly
- the secondary complications (pyoderma, Malassezia dermatitis and seborrhea)
(IF)
- do not use what in dogs!?
- The maintenance dose of oral prednisone or prednisolone should not exceed what?
- Always perform what at least once a year if corticosteroids or cyclosporine will be used as maintenance therapy.
- Client education is essential for the successful treatment of atopic dermatitis.
- injectable steroids
- 0.5 mg/kg given every-other-day.
- a chemistry profile, urinalysis and urine culture