ZOONOTIC EXOTIC DISEASES Flashcards
Dx of animals w/c are not and no longer present in country based on the classificatioon of OIE listings of diseases, A and B.
exotic diseases
neurological disorder affecting cattle
mad cow dz
BOVINE SPONGIFORM ENCEPHALOPATHY
misfolded proteins
○ Abnormal conformation of proteins
○ Non-living organisms
prions
Creutzfeldt-Jacobson syndrome
BSE
first detected sa dz na to na CS
san nadiagnose una tong dz na to
ano CFR
kelan nnakiikiita CS ng dz na to
scrapie
BSE - UK europe
100%
mature. 2-8 yrs
Foodborne exposure to prions
- Ingestion (Classical BSE)
- Associated with meat and bone meal
- Meat products from slaugther houses
- Have come frome infected animals
BSE
what form of BSE:
Cannot be associated with foodborne
- Basta sa old animals
- Natural occuring type of BSE in older
animals
atypical
After ingestion, prions replicate in __________
peyer’s patches
Purple circular areas = villi = intestines
dz where u need to be Extra precautions in performing necropsy
BSE
- Loss of body condition
- Behavior - reluctance to move, go from
one area to other - Reluctant to be milked
- Decrease milk yield
- Stares at the wall
- Hyperesthesia
- Inc sensitivity to touch and sound
- Changes in temperament
- Becomes aggressive
- Hindlimb ataxia
- If downer cow = cull
BSE
clinincal exam pang bSE
bang flash clipboard stick
what part of the brain ang sinusubmit sa histopath pag BSE
spongiform: intracytoplasmic Vacuolation in neurons ____
brainstem
grey matter
gold standard nng BSE
tx for BSE
Immunohistochemistry
no tx! high risk animals should NNOT be consumed like downner cows
Also known chlamydophila abortion ovine enzootic abortion
caused by:???
main source?
Transmission
OVINE ENZOOTIC ABORTION OR ENZOOTIC
ABORTION OF EWES
Chlamydophila abortus
birthing fluid and placenta vaginal
discharge, placenta and aborted fetus
Ingestion organisms - aerosols
Zoonotic implications ng OVINE ENZOOTIC ABORTION OR ENZOOTIC
ABORTION OF EWES
- Resp infexn
- Abortion
- Stillbirth
pre term labor