ZOONOTIC EXOTIC DISEASES Flashcards

1
Q

Dx of animals w/c are not and no longer present in country based on the classificatioon of OIE listings of diseases, A and B.

A

exotic diseases

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2
Q

neurological disorder affecting cattle
mad cow dz

A

BOVINE SPONGIFORM ENCEPHALOPATHY

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3
Q

misfolded proteins
○ Abnormal conformation of proteins
○ Non-living organisms

A

prions

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4
Q

Creutzfeldt-Jacobson syndrome

A

BSE

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5
Q

first detected sa dz na to na CS
san nadiagnose una tong dz na to
ano CFR
kelan nnakiikiita CS ng dz na to

A

scrapie
BSE - UK europe
100%
mature. 2-8 yrs

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6
Q

Foodborne exposure to prions
- Ingestion (Classical BSE)
- Associated with meat and bone meal
- Meat products from slaugther houses
- Have come frome infected animals

A

BSE

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7
Q

what form of BSE:
Cannot be associated with foodborne
- Basta sa old animals
- Natural occuring type of BSE in older
animals

A

atypical

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8
Q

After ingestion, prions replicate in __________

A

peyer’s patches
Purple circular areas = villi = intestines

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9
Q

dz where u need to be Extra precautions in performing necropsy

A

BSE

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10
Q
  • Loss of body condition
  • Behavior - reluctance to move, go from
    one area to other
  • Reluctant to be milked
  • Decrease milk yield
  • Stares at the wall
  • Hyperesthesia
  • Inc sensitivity to touch and sound
  • Changes in temperament
  • Becomes aggressive
  • Hindlimb ataxia
  • If downer cow = cull
A

BSE

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11
Q

clinincal exam pang bSE

A

bang flash clipboard stick

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12
Q

what part of the brain ang sinusubmit sa histopath pag BSE

spongiform: intracytoplasmic Vacuolation in neurons ____

A

brainstem
grey matter

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13
Q

gold standard nng BSE
tx for BSE

A

Immunohistochemistry
no tx! high risk animals should NNOT be consumed like downner cows

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14
Q

Also known chlamydophila abortion ovine enzootic abortion
caused by:???
main source?
Transmission

A

OVINE ENZOOTIC ABORTION OR ENZOOTIC
ABORTION OF EWES

Chlamydophila abortus

birthing fluid and placenta vaginal
discharge, placenta and aborted fetus

Ingestion organisms - aerosols

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15
Q

Zoonotic implications ng OVINE ENZOOTIC ABORTION OR ENZOOTIC
ABORTION OF EWES

A
  • Resp infexn
  • Abortion
  • Stillbirth
    pre term labor
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16
Q

CS ng OVINE ENZOOTIC ABORTION OR ENZOOTIC
ABORTION OF EWES

Diagnosis ng OVINE ENZOOTIC ABORTION OR ENZOOTIC
ABORTION OF EWES

necropsy findinigs: puro sa placennta lang wala sa fetus t or f
vax?

A

Abortion sa late pregnancy

  • Culture - definitive
  • Complement fixation test - Western blot
  • ELISA
  • For surveillance

t
yes

17
Q

Widespread in cattle in EU
- Caused by mycobacterium avium subspecies paratuberculosis
primarily spread via?

thiis dz ay same with ________ na nagrereplicate sa peyers AFTER inngestion

A

JOHNE’S DISEASE (PARATUBERCULOSIS)

feces/nursing
BSE

18
Q

other routes transmission nng johnes dz/para
age risk factor
ZOONOTIC implication

A

Vectors (oriental cockroach, earthworms,
adlut dipterans, ovine trichostrongylid
larvae)

amitraz dips

under 30 days

Crohn’s dz: Enteritis in humans

19
Q

4 stages of dz in cattle

A

stage 1 silent innfection shedding
2 infertility, mastitis
3 - loss bw, low milk, diarrhea WTHOUT blood (clinical dz)
4 - emaciation most obv (adv clinincal)

20
Q

diagnostic test for johnsn dz in cattle
tx?

A

Fecal culture
- Most reliable
- 100% specificity and sensitivity
- Advantage: Detect silent infections

none. non vax prevention of nnew inf lang

21
Q

Tick-transmissted
- Most pathogenic viral dz of small ruminants

what is variant in asia
what genuns annd fam?
san nagcirculate
vectors nnito? meron sa pinas?

A

nairobi sheep dz

Ganjam virus
genus Nairovirus of family Bunyavirdae
- Sri lanka - nagcirculate

Brown ear tick - rhipicephalus
appendiculatus: wala sa ph
Bont tick(amblyoma variegatum)

22
Q

primary nakikita sa nnecropsy nng nairobi sheep dz
main organ affected?

may tx? may vax? meron sa pinnas report?

A

SplenomealyHemorrhages - primary
Abomasum - main organ affected
Zebra stripes

no tx; vax only; wla

23
Q

Coxiella burnetti in cattle and waterbuffaloes, family rickettsiaceae

A

q fever

24
Q

Bioterrorism like anthrax

mainn reservoirs?

ano transmission

A

q fever
cattle goat and sheep

(1) Sylvatic
- Wild animals’ cycle
- Birds to small mammals to rodents -

(2) domestic cycle
- Via tick bites
- Inhalation main in humans
- Transmission occurs During parturition
- Contaminated dust,
beddings, fomites, contaminated placenta, abortion materials,

25
Q
  • Fever
  • General malaise
  • headache
  • Pneumonitis
  • Hepatitis
  • Meningoenceephalitis
  • endocarditis

sa necrop san sya same

A

q fever
BSE

26
Q

anong def diagnosis ng q fever

A

culture

27
Q

Caused by prion Behavioral change - Tremors
- pruritis
- Locomotor disorder - Wasting

A

scrapie

28
Q

Causes influenza-like disease in humans
Caused by a genus Vesiculovirus, family rhabdoviridae
- Endemic in south america, central america and parts of mexico

San sya close na dz
most susceptible animal

A

VESICULAR STOMATITIS
FMD; di nagsshow ung sheep at goats
cattle

29
Q

Causes influenza-like disease in humans
Caused by a genus Vesiculovirus, family rhabdoviridae
- Endemic in south america, central america and parts of mexico

San sya close na dz
most susceptible animal

A

VESICULAR STOMATITIS
FMD;
cattle; di nagsshow ung sheep at goats

30
Q

methods of transmission

A

biologically transmitted

  • Black Flies/sanndfly, biting midgest, mosq
  • Lay eggs in flowing bodies of water (rivers)
  • Bcos their larvae is highly dependent on O2
31
Q

gold standard ng vesicular stomatitis

tx:?
vax?

A

virus isolation

supportive
vax

32
Q

also known as streptotrichosis, lumpy wool disease (sheep), & strawberry footrot

caused by?

equivalent sa eq?

A

DERMATOPHILOSIS
Dermatophilus congolensis
Rain rot or rain scald

33
Q

Obligate pathogen: only found in animals
In the environment, only spores are found

t or f

A

t

34
Q

sa dermatophilosis, ano stages ng lesioins

A

Stage 1 - matting of hairs; “paintbrush” lesions
stage 2 - Scab formation
Stage 3 - formation of wart-like lesions

35
Q

Pyramid shaped scabs
- proliferative dermatitis in the coronet to the
carpus or hock

what animal dermatophilosis
gram ano
tx ano
prvention

A

sheep
positive, railrode appearance
Antibiotics (erythromycin, penicillin G,
tetracycline)
- Lime sulfur
- Insecticide (for ectoparasites)
- Disinfectants (povidone iodine,
chlorhexidine)

prevenntionn zinc skin