Zoonoses Flashcards

1
Q

What are zoonoses?

A

Infections that can pass between living animals and humans

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2
Q

What is the source of zoonoses?

A

The animal

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3
Q

What is anthroponosis?

A

A reverse of zoonoses - human infects animal

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4
Q

What are examples of bacterial zoonoses?

A
Salmonella
Campylobacter
Shigella
Anthrax
Brucella
Ecoli
Leptospirosis
Plague
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5
Q

What are examples of viral zoonoses?

A
Rabies
Bird flu
Crimean-congo haemorrhagic fever
Ebola
Rift valley fever
West nile fever
Yellow fever
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6
Q

What are examples of parasitic zoonoses?

A
Cysticerosis
Echinococcosis
Toxoplasmosis
Trichinellosis
Visceral larva migrans
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7
Q

What are examples of fungal zoonoses?

A

Dermatophytoses

Sporotrichosis

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8
Q

How is rabies transmitted?

A

Bite of an infected animal

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9
Q

What are the most common animals for rabies to be transmitted from?

A

Dogs and bats

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10
Q

What are features of rabies?

A
Malaise
Headache
Fever
Over production of saliva and tears
Unable to swallow
Mania
Death by respiratory failure
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11
Q

How is rabies diagnosed?

A

PCR of saliva or CSF, but difficult and often is confirmed in post mortem

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12
Q

Is rabies fatal if untreated?

A

Yes

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13
Q

How is rabies managed?

A

Immediate prophylaxis after bite - human rabies immunoglobulin
4 doses of rabies vaccine over 14 days

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14
Q

How is brucellosis spread?

A

Milking infected animals
During parturition
Handling carcasses of infected animals
Consumption of unpasteurised milk

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15
Q

What are the three types of brucella?

A

Melitensis
Suis
Abortus

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16
Q

What animals can spread brucella to humans?

A
Goats
Sheep
Camels
Pigs
Cattle
Buffalo
17
Q

How does acute brucellosis present?

A
High undulant fever
Weakness
Headaches
Drenching sweats
Splenomegaly
Lasts 1-3 weeks
18
Q

How does subacute brucellosis present?

A

Fever and joint pains

Lasts over 1 month

19
Q

How does chronic brucellosis present?

A
Flu-like symptoms
Malaise
Depression
Chronic arthritis
Endocarditis
Epididymo-orchitis
Meningism
Splenomegaly
20
Q

How is brucellosis treated?

A

Long acting doxyxycline for 2-3 months
Rifampicin
IM gemtamycin for first week

21
Q

How can humans acquire leptospirosis?

A

Direct contact with the animal

Contact with environment

22
Q

What are features of leptospirosis?

A

Undifferentiated fever, myalgia, headaches, abdominal pain

23
Q

What are features of severe leptospirosis?

A

Weil’s disease

Pulmonary haemorrhage

24
Q

What is Weil’s disease?

A

Triad of jaundice, acute kidney injury, bleeding

25
Q

How is leptospirosis diagnosed?

A

Consider history - cattle farmer or exposure to water or rats
Culture
ELISA - not ideal

26
Q

How is leptospirosis treated?

A

Doxycycline for mild disease, IV penicillin if severe

Dialysis and ventilation if required

27
Q

What is Lyme Borrelios transmitted by?

A

Ticks - ixodes ricinus in Europe

28
Q

What is erythema migrans?

A

Lesions of redness on the body

29
Q

How long after initial tick bite does erythema migrans present?

A

3-90 days

30
Q

What is acrodermatitis chronica atroficans?

A

Extensor surfaces become blueish-red, peripheral neuropathy is common

31
Q

What are features of Lyme’s?

A
Erythema migrans
Acrodermatitis chronica atroficans
Lymphocytoma
Neuroborreliosis
Carditis
Arthritis
32
Q

What is neuroborreliosis?

A

Triad of facial nerve palsy, radicular pain, and lymphocytic meningitis

33
Q

How is Lyme’s diagnosed?

A

Erythema migrans
Serology if anthrodermatitis chronica atroficans
Neuro symptoms, blood and CSF serology for neuroborreliosis

34
Q

How is Lyme’s treated?

A

Oral doxycycline
Oral amoxicillin
IV ceftriaxone

35
Q

How long is treatment taken for Lyme’s?

A

21 days