Travel related infection Flashcards

1
Q

What makes travellers more vulnerable to infection?

A

Temptation to take risks away from home
Different epidemiology of some diseases
Incomplete understanding of health hazards
Stress of travel
Refugees - deprivation, malnutrition, disease, injury

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2
Q

What are examples of climate or environmental related health problems?

A
Sunburn
Heat exhaustion
Fungal infections
Bacteria skin infections
Cold injury
Altitude sickness
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3
Q

What infections are controllable by improved sanitation?

A
Travellers diarrhoea
Typhoid
Hep A or E
Giardiasis
Amoebiasis
Helminth infections
Viral gastroenteritis
Food poisoning
Shigella dysentry
Cholera
Cryptosporidiosis
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4
Q

What infections are controllable by immunisation?

A

Poliomyelitis

Diphtheria

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5
Q

What infections are controllable by education?

A

HIV

STDs

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6
Q

What are examples of water-related infections?

A
Schistosomiasis
Leptospirosis
Liver flukes
Strongyloidasis
Hookworms
Guinea worms
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7
Q

What are examples of arthropod-borne infections?

A
Malaria - mosquitos
Dengue fever - mosquitos
Rickettsial infections - ticks
Leishmaniasis - Sand flies
Trypanosomiasis - tsetse fly
Filariasis - mosquitos
Onchocerciasis - black flies
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8
Q

What are emerging infectious diseases?

A
Zika virus in latin america and caribbean
Ebola virus in west Africa
Swine flu worldwide
Avian flu in China
SARS 
West Nile Virus
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9
Q

What are the important tropical diseases that need to be known?

A
Malaria
Typhoid
Dengue Fever
Schistosomiasis
Rickettsiosis
Viral haemorrhagic fevers
Zika fever
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10
Q

What is the vector for malaria?

A

Female Anopheles mosquito

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11
Q

What species causes severe malaria?

A

Plasmodium falciparum

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12
Q

What are symptoms of malaria?

A
Fever
Rigors
Aching bones
Abdo pain
Headache
Dysuria
Frequency
Sore throat
Cough
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13
Q

What are possible signs of malaria?

A

Splenomegaly
Hepatomegaly
Mild jaundice

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14
Q

What are potential complications of malaria?

A
Cerebral malaria
Blackwater fever
Pulmonary oedema
Jaundice
Severe anaemia
Algid malaria
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15
Q

What is Blackwater fever?

A
Severe intravascular haemolysis
high parastiaemia
profound anaemia
haemoglobinuria
acute renal failure
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16
Q

What are features of cerebral malaria?

A

Arching posture of back
Small brain infarcts
Convulsions
Hypoxia

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17
Q

What drugs should be used to treat malaria?

A

Malarone
Riamet
Quinone

18
Q

How is Malaria diagnosed?

A

Thick and thin bloodfilms
Quantitative buffy coat
Rapid antigen tests

19
Q

What are features indicative of complicated malaria?

A
One or more of:
Impaired consciousness or seizures
Hypoglycaemia
Parasite count >2%
Haemoglobin<8mg/dL
Spontaneous bleeding
Haemoglobinuria
Renal impairment
pH<7.3
Pulmonary oedema or ARDS
Shock
20
Q

How is complicated malaria treated?

A

IV quinine plus oral doxycycline

21
Q

How is malaria controlled?

A

Mosquito breeding sites - drainage of standing water
Larvacides
Mosquito killing sprays
Human behaviour

22
Q

What are causative organisms of typhoid fever?

A

Salmonella typhi

Salmonella paratyphi

23
Q

What are clinical features in the 1st week of typhoid fever?

A
Fever
Headache
Abdominal discomfort
Constipation
Dry cough
Relative bradycardia
Neutrophilia
Confusion
24
Q

What are clinical features in the 2nd week of typhoid fever?

A
Fever peaks at 7-10 days
Rose spots
Diarrhoea begins
Tachycardia
Neutropenia
25
What are complications in the 3rd week of typhoid fever?
Intestinal bleeding Perforation Peritonism Metastatic infections
26
How is typhoid fever diagnosed?
Blood culture Urine cultures Stool culture Bone marrow culture
27
How is typhoid fever treated?
Oral azithromycin - uncomplicated | IV ceftriaxone - complicated
28
What species transmits dengue fever?
Aedes aegypti mosquito
29
What are classical features of Dengue fever?
``` Sudden fever Severe headache, retro-orbital pain Severe myalgia and arthralgia Macular/maculopapular rash Haemorrhagic signs - petechiae, purpura, positive tourniquet test ```
30
How is dengue diagnosed?
``` Thrombocytopenia Leucopenia Elevated transaminases Positive tourniquet test PCR Serology ```
31
What are potential complications of dengue?
Dengue haemorrhagic fever | Dengue shock syndrome
32
What are vector organisms for schistosomiasis?
Freshwater snails
33
What species cause schistosomiasis?
S.haematobium S.mansoni S.japonicum
34
What is the progression of schistosomiasis?
``` Swimmers itch Invasive stage Katayama fever Acute disease Chronic disease ```
35
What are features of the invasive stage of schistosomiasis?
Cough Abdominal discomfort Splenomegaly Eosinophilia
36
How is schistosomiasis diagnosed?
Antibody tests Ova in stools and urine Rectal snip
37
How is schistosomiasis treated?
Praziquantel 20mg/kg
38
What are clinical features of rickettsiosis?
``` Abrupt onset swinging fever Headache Confusion Endovasculitis Rash Bleeding ```
39
How is rickettsiosis diagnosed?
Serology
40
How is rickettsiosis treated?
Tetracycline
41
What are features of zika?
``` Mild symptoms Headache Rash Fever Malaise Conjunctivitis Joint pains Can cause microcephaly and other neuro problems in pregnancy ```