Zika virus facts Flashcards

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1
Q

symptoms

A

fever, muscle pain, rash

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2
Q

transmission

A

aedes species mosquito

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3
Q

what is the diagnosis

A

blood/ urine test

neutralisation assay

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4
Q

cure?

A

no cure or vaccine

rehydration therapy

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5
Q

what conditions can Zika virus lead to

A

Guillain barre

microcephaly

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6
Q

Baltimore class

A
class 4 
(+ ssRNA)
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7
Q

what is the size of zika virus

A

50 nm

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8
Q

name a large and small virus

A

Zika virus & Ebola virus (900nm)

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9
Q

what is the structure of zika virus

A

envelope & nucleocapsid
spherical
has a poly protein

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10
Q

what type of virus is it

A

arbovirus

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11
Q

what family does it belong to

A

falviviridae

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12
Q

what is the zoonotic origin of it

A

macacque monkeys in the zika forest (africa)

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13
Q

what are some known relatives

A

yellow fever

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14
Q

what moved zika worldwide

A
slave trade (old outbreaks)
international travel (new outbreaks)
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15
Q

describe the 2007 outbreak

A

2/3 showed no symptoms

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16
Q

what changed from the 2007 Malaysia outbreak to the 2015 brazil outbreak

A

first deaths occurred in 2015

- virus became slightly more virulent

17
Q

describe the arbovirus transmission cycle

A

requires an insect vector
sylvatic cycle = cycles between vectors and monkeys
reaches a human and enters urban cycle = cycles between human host and vector