Zero to Finals Flashcards
61 year old smoker with haemotysis?
Diagnosis and types?
Lung cancer
Adenocarinoma (40%)
Squamous cell carincoma (20%)
Small cell lung cancer (20%)
61 year old smoker with haemotysis.
Cause of a hoarse voice?
Recurrent laryngeal nerve palsy
61 year old smoker with haemotysis.
Cause of partial ptosis, anhidrosis and miosis?
Horner’s syndrome -> Pancoast’s tumour
61 year old smoker with haemotysis.
Cause of hyponatraemia?
SIADH -> SCLC
61 year old smoker with haemotysis.
Investigation for getting histological diagnosis?
Bronchoscopy with EBUS and biopsy
61 year old smoker with haemotysis.
Scan for increased metabolic activity in metastasis?
Position emission tomography (PET-CT)
61 year old smoker with haemotysis.
Malignancy associated with asbestos
Mesothelioma
72 year old presents with a productive cough, fever and breathlessness. A CXR shows a right sided, middle zone consolidation.
Diagnosis?
Pneumonia
72 year old presents with a productive cough, fever and breathlessness. A CXR shows a right sided, middle zone consolidation.
Criteria for hospital acquired pneumonia?
> 48hrs after admission
72 year old presents with a productive cough, fever and breathlessness. A CXR shows a right sided, middle zone consolidation.
Scoring system?
CURB 65
Confusion Urea >7 Resp rate >/ 30 Blood pressure <90 systolic/< or equal to 60 diastolic Over 65 years old
72 year old presents with a productive cough, fever and breathlessness. A CXR shows a right sided, middle zone consolidation.
Most common cause?
Streptococcus pneumoniae
72 year old presents with a productive cough, fever and breathlessness. A CXR shows a right sided, middle zone consolidation.
Atypical cause with hyponatraemia?
Legionella pneumoniae
72 year old presents with a productive cough, fever and breathlessness. A CXR shows a right sided, middle zone consolidation.
Atypical cause with erythema multiforme?
Mycoplasma
72 year old presents with a productive cough, fever and breathlessness. A CXR shows a right sided, middle zone consolidation.
Atypical cause with farmer?
Coxiella burnetti (Q-fever)
72 year old presents with a productive cough, fever and breathlessness. A CXR shows a right sided, middle zone consolidation.
Atypical cause with parrot breeder?
Chlamydia psittaci
72 year old presents with a productive cough, fever and breathlessness. A CXR shows a right sided, middle zone consolidation.
Atypical cause with chronic wheezy child?
Chlamydophilia
19 year old with chronic nocturnal cough and wheezing episode.
Diagnosis?
Asthma
19 year old with chronic nocturnal cough and wheezing episode.
First line testing with NICE guidelines?
Fractional exhaled nitrous oxide (DeNO)
Spirometry with reversibility testing
19 year old with chronic nocturnal cough and wheezing episode.
Treatment step 1 & 2?
Step one: SABA
Step two: Low dose inhaled corticosteroids
19 year old with chronic nocturnal cough and wheezing episode.
Mechanism of action of salneterol?
Long acting beta 2 agonist
19 year old with chronic nocturnal cough and wheezing episode.
Mechanism of action of tiotropium?
Long acting muscarinic antagonist
19 year old with chronic nocturnal cough and wheezing episode.
Mechanism of action of montelukast?
Leukotriene receptor antagonist
19 year old with chronic nocturnal cough and wheezing episode.
Mediations used in moderate attack?
Nebulised salbutamol
Nebulised ipratropium bromide
Steroids
Long term smoker with a chronic cough and recurrent chest infections?
Diagnosis?
COPD
Long term smoker with a chronic cough and recurrent chest infections?
Dyspnoea scale?
MRC Dyspnoea Scale
Long term smoker with a chronic cough and recurrent chest infections?
Diagnostic test?
Spirometry
Long term smoker with a chronic cough and recurrent chest infections?
FEV1/FVC ratio?
< 0.7
Long term smoker with a chronic cough and recurrent chest infections?
Step 1 of treatment?
Short-acting bronchodilators
Long term smoker with a chronic cough and recurrent chest infections?
Step two of treatment if asthmatic?
LABA + inhaled corticosteroids
Long term smoker with a chronic cough and recurrent chest infections?
Step 2, no asthmatic features?
LABA + LAMA
Long term smoker with a chronic cough and recurrent chest infections?
Treatment of an acute exacerbation?
- Bronchodilators (eg Ipratropium)
- Steroids (eg Prednisolone)
- Antibiotics if infection)
Long term smoker with a chronic cough and recurrent chest infections?
Target sats when retaining CO2?
88-92%
Long term smoker with a chronic cough and recurrent chest infections?
Criteria for non-invasive ventilation (NIV)?
pH < 7.35
PaCO2 > 6 despite treatment
74 year old non-smoker with bibasal fine inspiratory crackles?
Fingernail changes?
Clubbing
74 year old non-smoker with bibasal fine inspiratory crackles?
Diagnosis?
Idiopathic pulmonary fibrosis
74 year old non-smoker with bibasal fine inspiratory crackles?
Diagnostic test?
High resolution CT
74 year old non-smoker with bibasal fine inspiratory crackles?
Characteristic test finding?
“Ground glass” appearance to lungs
74 year old non-smoker with bibasal fine inspiratory crackles?
Life expectancy post diagnosis?
2-5 years
74 year old non-smoker with bibasal fine inspiratory crackles?
Medication to slow disease progression?
- Pirfendione
- Nintedanib
74 year old non-smoker with bibasal fine inspiratory crackles?
Medication that cause similar lung pathology?
- Amiodarone
- Cyclopathosphamide
- Methotrexate
- Nitrofurantoin
21 year old tall slim male with sharp chest pain on inspiration and shortness of breath.
Diagnosis?
Pneumothorax
21 year old tall slim male with sharp chest pain on inspiration and shortness of breath.
Investigations?
Chest X-ray
21 year old tall slim male with sharp chest pain on inspiration and shortness of breath.
Cutoff for treatment if not short of breath?
More than 2cm rim of air on CXR
21 year old tall slim male with sharp chest pain on inspiration and shortness of breath.
Treatment options?
- Aspiration
- Chest Drain
56 year old with progressive shortness of breath?
Diagnosis?
Pulmonary hypertension
56 year old with progressive shortness of breath?
5 groups of causes?
- Primary pulmonary hypertension
- Left sided heart failure
- Chronic lung disease (eg COPD)
- Pulmonary vascular disease (eg PE)
- Miscellaneous (eg sarcoidosis)
56 year old with progressive shortness of breath?
Clinical skills?
- Tachycardia
- Hepatomegaly
- Raised JVP
- Peripheral oedema
56 year old with progressive shortness of breath?
ECG changes?
- Right ventricular hypertrophy
- Right axis deviation
- Right bundle branch block
56 year old with progressive shortness of breath?
Chest Xray?
- Dilated pulmonary veins
- Right ventricular hypertrophy
56 year old with progressive shortness of breath?
Raised blood test?
NR-PRO BNP
30 year old black woman with a dry cough and shortness of breath?
Diagnosis?
Sarcoidosis
30 year old black woman with a dry cough and shortness of breath?
What are granulomas?
Nodules of inflammation full of macrophages
30 year old black woman with a dry cough and shortness of breath?
Tender lumps on shins?
Erythema nodosum
30 year old black woman with a dry cough and shortness of breath?
Screening blood test?
Serum ACE
30 year old black woman with a dry cough and shortness of breath?
Electrolyte abnormality?
Hypercalcaemia
30 year old black woman with a dry cough and shortness of breath.
CXR finding?
Hilar lymphadenopathy
30 year old black woman with a dry cough and shortness of breath?
Gold standard investigation?
Histology (biopsy)
30 year old black woman with a dry cough and shortness of breath?
First line treatment?
Steroids
57 year old obese man presents with snoring and daytime sleepiness. His wife reports episodes where he stops breathing during sleep.
Diagnosis?
Obstructive Sleep Apnoea
57 year old obese man presents with snoring and daytime sleepiness. His wife reports episodes where he stops breathing during sleep.
Risk factors not mentioned?
- Smoking
- Alcohol
57 year old obese man presents with snoring and daytime sleepiness. His wife reports episodes where he stops breathing during sleep.
Key morning symptom?
Headache
57 year old obese man presents with snoring and daytime sleepiness. His wife reports episodes where he stops breathing during sleep.
Scale?
Epworth sleepiness scale
57 year old obese man presents with snoring and daytime sleepiness. His wife reports episodes where he stops breathing during sleep.
Refer to?
ENT/Sleep clinic
57 year old obese man presents with snoring and daytime sleepiness. His wife reports episodes where he stops breathing during sleep.
Step after correcting risk factors?
Continuous positive airway pressure (CPAP) machine used during sleep
57 year old obese man presents with snoring and daytime sleepiness. His wife reports episodes where he stops breathing during sleep.
Surgical prodecure?
Uvulopalatopharyngoplasty
UPPP