Youth Personality and Somatic Symptom Disorders Flashcards

1
Q

Problem with PD diagnosis in adolesence (4)

A

(1) DSM focuses on adulthood
(2) “enduring criteria”: doesn’t applies to youth (there’s only so much time it can be)
(3) “Deviates from norms” - typical in adolescence
(4) “Onset in adolescence or early adulthood”: Confusing, cuz it’s also extremely rare in adolescence (but the onset is in adolescence?)

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2
Q

PD symptoms in adolescence are bidirectionally related to …

A

severe behavioural and developmental consequences
=> E.g. Trauma → Insecure child → act out with friends and family → kicked out of home again → stop going to school (…) bidirectional

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3
Q

Problems with seeing PD diagnosis as categorical (4)

A
  • Inter-category comorbidity
  • Intra-category heterogeneity: Hundreds of diff presentations of BPD
  • Arbitrary diagnostic thresholds
  • Stigma of rigid categories
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4
Q

PD Diagnosis: Dimensional

A

Spectrum from maladaptive to adaptive

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5
Q

Advantages of dimensional approach to PDs (6)

A

(1) Emphasizes multi-dimensionality of PDs
(2) Reduces stigma
(3) Eases goal-setting in treatment
=> e.g. You can see which specific traits are causing the problem
(4) Psychopathology manifests differently in youth
(5) Normative behaviour at one age could be pathological at another
(6) Discrepancies caused by multi-informant report

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6
Q

Alternative Model of Personality Disorders (AMPD)

A
  • HYBRID model of Dimensional and Categories. Not used clinically.
  • Diagnoses: ASPD, AvPD, BPD, NPD, OCPD, StPD, PD-TS (Still retains 6 categories)
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7
Q

Alternative Model of Personality Disorders (AMPD): Criteria A (see image)

A

Criteria A: Level of personality Functioning
- 2 domains: Self and Interpersonal Functioning
- Self-functioning:
=> Identity = How you think of yourself, Self-direction = your goals, what motivates you
- Interpersonal functioning:
=> Intimacy = closeness to others, how you’re able to interact in close relationships; Empathy

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8
Q

Alternative Model of Personality Disorders (AMPD): Criteria B (see image)

A
  • Criteria B: Pathological Personality Traits
    • Negative Affectivity (i.e. Neuroticism): how much negative affect you feel at baseline
    • Detachment (i.e. Low extraversion)
    • Disinhibition (i.e. low Consciousness)
    • Dissociality (i.e. low Agreeableness)
    • Anankastia (i.e. low Openness)
      -> Sets up treatment goals in a nice way
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9
Q

Diagnosis of BPD in youth: reliability and validity

A

Evidence in favour of reliability and validity of BPD diagnosis in youth, just as in adults

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10
Q

Main markers of adolescent BPD (bit diff from adulthood) (2)

A
  • Self-harm
  • Risk-taking
    => BUT… Poorer impulse control in adolescence in general, need for age-specific norms
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11
Q

How young to have a diagnosis?

A

No lower limit. Can be as low as 12-13yo

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12
Q

BPD Etiology (2)

A
  • Genes/Biology:
    => Family history of: Substance use, anxiety, antisocial personality, mood disorders + heritability
  • Environment
    => More likely to have experienced childhood abuse/neglect (ACEs)
    => Childhood sexual abuse a risk factor for both BPD and SEVERITY of BPD
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13
Q

BPD Etiology: Major Theoretical Stances – Linehan’s biosocial theory (4)

A

(1) Invalidating environment (real or perceived)
=> E.g. sensitive child (combination of family dynamic + sensitivity + responsibilities) → cannot be herself, cannot do ‘wrong’
=> When emotions don’t matter, you push them away → this causes dysfunction in regulation of emotion → over time: BPD
(2) Belief that one’s feelings/thoughts do not matter
(3) Reduced ability to recognize and label emotions
(4) Dysfunction in the experience and regulation of emotions

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14
Q

BPD Etiology: Major Theoretical Stances – Fonagy’s mentalization model (3)

A

(1) Vulnerability to emotional distress
(2) Hyper-responsiveness of attachment systems
(3) Deficits in mentalizing → poor development of the self
E.g. Sensitive children put through a lot of emotional stress… → hyper responsiveness in attachment system (very attuned to relationships and what could go wrong) → deficits of mentalizing (i.e. think of what other pple think) → hypermentalizing (”he thinks he hates me…”) → kills self-esteem and poor development of the self

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15
Q

BPD Course (3)

A

(1) Starts in childhood: Extremes in temperament
=> Novelty seeking & Harm avoidance: highly correlated with later BPD
(2) As temperament starts to grow → Personality: Can turn into e.g. negative affectivity
=> If high on extremes, can eventually become early internalizing/externalizing problems (often comorbid with BPD)
(3) While you’re still up here (temperamental difficulties), everybody else is maturing
-> Conflict look different, maladaptive behavior
-> Can develop into more solidified early onset of BPD in adolescence (or BPD traits)

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16
Q

Theory: People grow out of BPD (2)

A

(1) Decent amount of remission
(2) BUT: Because there’s so much overlap between BPD and other internalizing/externalizing symptoms, theory that it’s not actual remission but a conversion of remission into e.g. MDD, GAD (…)
=> Presentation of underlying pathology can change so much that it seems like remission

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17
Q

BPD Evidence-based Treatment (2)

A

(1) Dialectical Behavioural Therapy (DBT)
(2) Mentalization-based Treatment (MBT)

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18
Q

DBT (Dialectical Behavioural Therapy)

A

(1) Synthesis of change and acceptance
(2) Targets emotion dysregulation, distress tolerance, and interpersonal difficulties
=> Greater reductions in NSSI, depression, and BPD symptoms than TAU in adolescence
-> Combined therapy approach of affirmation, unconditional regard… with CBT

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19
Q

DBT: Main features of stress tolerance (3) components

A
  • Emotion regulation: lot of understanding and self-validating - catch yourself before you go to distress (10/10)
  • Reduce body temperature, intense exercise
  • Paced breathing and progressive muscle relaxation
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20
Q

DBT: Interpersonal difficulties

A

Teaching in a very clear way how to interact with others

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21
Q

Mentalization-based Treatment (MBT)

A

(1) Focus on hyper mentalizing
(2) Improves mentalization
(3) Reduces attachment avoidance
=> Greater reductions in self-harm and depression than TAU in adolescence

22
Q

DBT works rly well BUT: (2)

A

(1) Really intensive
(2) Limited availability

23
Q

Possible solution answering the inaccessibility of DBT (2) - study

A

Stepped care approach:
1- CDP
- Targeting “Adolescent Risky Behaviour Pathway”
- Targets self-harming behaviours (for everyone)
2- DBT-A
- Targeting “Psychopathological Pathway”
- Reserved for pple meeting a certain threshold of BPD symptoms
=> CDP was ONLY good in addressing non-suicidal self-injury (not good by itself)
=> No sig. differences between CDP + no DBT-A and CDP + DBT-A groups
-> Highlights difficulty treating adolescent BPD

24
Q

Is PD just trauma?

A

No.
(1) About 30% of adults diagnosed with BPD with no ACEs (=adverse childhood experiences)
(2) Multifinality of mental health outcomes associated with trauma

25
Complex PTSD vs BPD
(1) Complex PTSD - Affective dysregulation - Self worthlessness/guild - Interpersonal detached (2) BPD - Instability - Paranoid/Dissociative - Unstable relationships - Self-harm - Impulsivity/Temper - Unstable sense of self => BPD very likely to have PTSD (~50%) => PTSD not likely to have BPD
26
... is most common somatic symptom. In children, ...
Pain In children, more commonly a single prominent symptom in children => Headache and abdominal pain most common combination
27
SSD in Youth: Biopsychosocial Etiology -- Reciprocal Maintenance Theory (see colours)
(1) Excessive and chronic sympathetic hyperarousal after cumulative or extreme ACEs ↔ psychological aspects of somatic symptoms (2) Moderate genetic heritability + Autonomic nervous system dysregulation (3) Somatic sx associated with heightened sensitivity to internal and external sensations, somatic hypervigilance, selective attention to threat (4) “Dose-Response”: More traumatic events associated with more (and more severe) somatic sx (5) Medical iatrogenesis (6) Learning + sociocultural norms
28
Medical iatrogenesis
A state of ill health or adverse effect caused by medical treatment (E.g. you like to be in the sick role and the sick role is reinforced more than it would be if you were experiencing mental heath symptoms)?
29
Youth with unexplained somatic symptoms more likely to have ... and ...
- Later anxiety disorders (46% vs. 18%) - Depressive disorders (57% vs. 29%)
30
Temperamental/personality characteristics in SSD (5)
- Negative affectivity - Behavioural inhibition (i.e. being shy) - Fear of uncertainty - Emotional unawareness/instability - Anxiety sensitivity
31
SSD Treatments (5)
(1) Cognitive-behavioural therapies - Ex. Treatment of Anxiety and Physical Symptoms (TAPS) - Decrease over 12-sessions from moderate to minimal somatic sx (2) Mindfulness-based therapies (3) Antidepressant medications (4) Family- and system-informed (5) Treating comorbid disorders => Treatments targeting anxiety and depression also effective for SSD
32
SSD, Anxiety, Depression: One Disorder? -- PROOFS for YES (6)
- High comorbidity and associations across lifespan - Conceptually linked - Overlap in heritability - Treatment for one, treatment for all - Dimensions of internalizing disorder - Impact on medical care
33
SSDs in the Medical Sphere
(1) Physician as “cultural arbiter” of legitimate illness (2) Lack of medical explanation taken as “nothing wrong” -> Can increase stigma from medical staff
34
SSDs and PDs: More Similar Than They Seem, how come? ()
(1) Somatization sx as PREDICTOR of adolescent BPD traits
35
Vicious cycle of chronic pain, harm avoidance (HA) and self-directedness (SD) (4)
(1) High HA leads to: anticipating pain with fearful and pessimistic thoughts (2) This disseminates into longstanding worry/rumination (3) Because of low SD, cannot define/pursue meaningful goals (4) Chronic disability and suffering
36
Problem with treatments
Need for novel treatments: => Treatment-resistant conditions
37
“Gold-standard” of psychotherapy + psychotropics: PROS (3)
- Complementary and interdisciplinary - Evidence of efficacy + effectiveness - Transdiagnostic approach
38
“Gold-standard” of psychotherapy + psychotropics: CONS (4)
- Limited accessibility of therapy - Does not work for everybody - Delayed onset of psychotropics - Side effects of psychotropics
39
What do we do, when all else fails? New approaches (2)
(1) Hypnosis (2) Psychedelic-Assisted Therapy
40
Hypnosis in Youth: PROS ()
(1) Safe intervention (2) Long history of use in pediatric settings (3) Can be clinician or self-directed (4) Children may be particularly hypnotizable
41
Hypnosis: Consists of (3)
(1) Induction of hypnotic state (2) Suggestions of sensory, cognitive-perceptual, or behavioural alterations (3) De-induction
42
Hypnosis Potential Applications in Youth (5)
(1) Reframe problems as solvable, conditions as manageable, build positive expectations (2) Change behavioural patterns (3) Control exaggerated reactivity to internal and external stimuli (4) Manage anxiety (5) Help process recent trauma or traumatic memories
43
Evidence for Hypnosis
RCTs: (1) Hypnotherapy > standard medical treatment after treatment (at 6 and 12 months) (2) Study on Hypnotherapy vs. progressive muscle relaxation vs. transcendental meditation => All reduced (until 9mo)
44
Hypnosis Caveats (4)
- A tool that must be practiced - May be more of an adjunct than the main therapeutic focus - Must be developmentally appropriate - Hypnotizability of people with PDs unclear
45
Psychedelic-Assisted Therapy def
- Serotonergic hallucinogens - MDMA, ketamine, other ”atypical psychedelics” - Used clinically as part of psychotherapy
46
Psychedelic-Assisted Therapy: Evidence & disorders (3)
Good evidence over 18 for treatment-resistant disorders - MDMA → PTSD - Psilocybin → Depression - Ketamine → Depression, Chronic pain
47
Psychedelic-Assisted Therapy: PROS
Very little risk of overdose, long-term side effects, or addiction for serotonergic hallucinogens
48
Psychedelic-Assisted Therapy: Mechanisms (4)
- Altered self-perception, reduced focus on the narrative self, disrupted default mode network - Increased introspection and psychological insight - Positive mood changes and a sense of unity/connectedness - Improvements in personality traits such as openness and empathy
49
Psychedelic-Assisted Therapy: Potential Gain for each PD cluster
- Cluster A – Maybe contraindicated so not really - Cluster B – Mostly yes! - Cluster C – More research needed but so far it's okay!
50
Psychedelic-Assisted Therapy: Potential Gain (AMPD criteria)
CRITERION A: Level of personality Functioning - Good for: identity, self-direction, intimacy - Meh for: empathy CRITERION B: Pathological Personality traits - Good for: negative affectivity, detachment, disinhibition, antogonism - Meh for: psychoticism
51
Psychedelic-Assisted Therapy: Evidence in Youth (2)
(1) Naturalistic study found that for adolescents without genetic vulnerability, lower psychotic and manic symptoms (2) Taking ayahuasca in religious setting associated with fewer psychiatric symptoms in adolescence
52
Psychedelic-Assisted Therapy in Youth: Safety, Ethical, & Legal Concerns (5)
- Bad trips - Latrogenic psychotic/manic symptoms - Medical risks of MDMA and ketamine - Possible negative effect on developing adolescent brain - Informed consent