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Histo Exam 1 > Written Exam One Q31 - Q60 > Flashcards

Written Exam One Q31 - Q60 Flashcards

1
Q
  1. Which is FALSE? Gap junctions:

A. provide for electrical communication between cells

B. are a part of an intercalated disc

C. connect adjacent osteocytic processes within canaliculi

D. are attached to actin filaments at zonulae adherentes

E. permit cAMP to move between connected cells

A

D. are attached to actin filaments at zonulae adherentes

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2
Q
  1. Which of the following is MISMATCHED?

A. simple squamous epithelium – mesothelium

B. simple squamous epithelium – endothelium

C. stratified squamous, keratinized – skin surface

D. stratified squamous, moist – vagina

E. transitional – gut lining

A

E. transitional – gut lining

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3
Q
  1. What is respiratory epithelium?

A. transitional

B. simple squamous

C. pseudostratified ciliated columnar with goblet cells

D. stratified columnar

A

C. pseudostratified ciliated columnar with goblet cells

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4
Q
  1. Which of the following is NOT a characteristic feature of an epithelium?

A. shows polarity

B. cover surfaces

C. have considerable ECM

D. highly cellular

E. forms barriers and compartments

A

C. have considerable ECM

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5
Q
  1. Which of the following pairs is MISMATCHED?

A. cytokeratins – zonula adherens

B. intermediate filaments – vimentin

C. hemidesmosome – attachment to the basal lamina

D. zonula occludens – epithelial cell polarity

A

A. cytokeratins – zonula adherens

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6
Q
  1. Each of the following is true of basement membranes EXCEPT:

A. reticular fibers are in the fibroreticular lamina

B. collagen IV is in the lamina densa

C. laminin and fibronectin are glycoproteins in the basal lamina

D. functions as a place for attachment of desmosomes

E. basal lamina often has both lamina rara and lamina densa

A

D. functions as a place for attachment of desmosomes

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7
Q
  1. Which of the following distinguishes an exocrine gland from an endocrine gland?

A. one demonstrates regulated secretion and the other demonstrates constitutive secretion

B. one secretes onto a surface or into a gland lumen that connects to a surface via a duct and the other secretes into connective tissues for distribution via the blood

C. an accumulation of secretory vacuoles in an acinar structure characterizes an endocrine gland while exocrine glands are simple or compound tubular structures

D. one secretes mucus and the other secretes protein-rich material

E. nothing that is evident in histologic sections

A

B. one secretes onto a surface or into a gland lumen that connects to a surface via a duct and the other secretes into connective tissues for distribution via the blood

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8
Q
  1. Cadherens are transmembrane proteins involved with which of the following cell junctions?

A. hemidesmosomes

B. focal contacts

C. tight junctions

D. zonula adherens

E. gap junctions

A

D. zonula adherens

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9
Q
  1. Endothelium is a term used to describe the epithelium of: A. Blood vessels B. Exocrine glands C. Lining of body cavities D. Skin
A

A. Blood vessels

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10
Q
  1. Endocrine glands release their product directly into/onto:

A. Body cavities such as the pleural cavity

B. Connective tissue, with subsequent uptake by the circulation

C. Ducts

D. The free surface of the epidermis

E. The lumen of hollow organs such as the small intestine

A

B. Connective tissue, with subsequent uptake by the circulation

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11
Q
  1. Which one of the following cellular junctions prevents free diffusion of solutes and water through the transepithelial paracellular space? A. Gap junction B. Hemidesmosome C. Adhesion belt D. Tight junction E. Macula adherens
A

D. Tight junction

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12
Q
  1. The defining characteristic of exocrine glands is the presence of

A. both serous and mucous acini in the secretory portion of the gland

B. myoepithelial cells between the secretory cells and the basal lamina

C. stored zymogen droplets in the apical portion of the secretory cell

D. ducts that convey the secretory product from the secretory cells to a body surface

E. columnar cells in the duct system that transport sodium and water to concentrate the secretion

A

D. ducts that convey the secretory product from the secretory cells to a body surface

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13
Q
  1. Fluorescently labeled molecules are microinjected into an epithelial cell. Ten minutes later, the presence of the probe molecules is detected in adjacent, uninjected cells. This is evidence that the cells are joined by

A. desmosomes B. adhesion belts C. gap junctions D. tight junctions E. junctional complexes

A

C. gap junctions

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14
Q
  1. The mammary gland is classified as an exocrine gland because of which one of the following characteristics?

A. Connective tissue capsule

B. Extraepithelial location

C. Association with myoepithelial cells

D. System of drainage ducts

E. Tubuloacinar secretory units

A

D. System of drainage ducts

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15
Q
  1. The terminal web of an epithelial cell is anchored peripherally to

A. adhesion belts

B. gap junctions

C. desmosomes

D. basal laminae

E. tight junctions

A

A. adhesion belts

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16
Q
  1. Which one of the following describes the secretory mechanism by which sebum is produced?

A. Apocrine B. Cytocrine C. Eccrine D. Holocrine E. Paracrine

A

D. Holocrine

17
Q
  1. A connexon is a structural component of the

A. adhesion belt B. macula adherens C. gap junction D. tight junction E. desmosome

A

C. gap junction

18
Q
  1. Consider the desmosome. Which of the following statements is TRUE?

A. Sometimes it is called a nexus.

B. Provides for the passage of large proteins from one cell to an adjacent cell.

C. Has a plaque formed of many connexons.

D. Facilitates metabolic coupling between adjacent cells.

E. A disc-shaped adhesion site between epithelial cells.

A

E. A disc-shaped adhesion site between epithelial cells.

19
Q
  1. A 24-year-old graduate student who has chronic lower respiratory tract infections seeks advice from an ear, nose and throat specialist. A biopsy of the student’s respiratory epithelium was examined via electron microscopy and found to have abnormal:

A. microvilli B. desmosomes C. cilia D. hemidesmosomes E. basal plasmalemma infoldings

A

C. cilia

20
Q
  1. Consider the characteristics of an epithelium. Which of the following is TRUE?

A. polarized

B. vascular

C. encased within a basal lamina

D. contain wide intercellular spaces

E. The only basic tissue that does not contribute to the wall of a blood vessel.

A

A. polarized

21
Q
  1. Synthesis of hyaluronin occurs in/on which of the following cell structures?

A. Golgi B. Lysosomes C. Late endosomes D. Rough endoplasmic reticulum (rER) E. Cell surface (plasma membrane)

A

E. Cell surface (plasma membrane)

22
Q
  1. Concerning collagen:

A. type IV is present in the lamina densa of basal laminae

B. type III of reticular fibers is stainable with silver

C. it is the most abundant protein of the body

D. all collagens exist as fibers

E. only “A”, “B” and “C” are correct

A

E. only “A”, “B” and “C” are correct

23
Q
  1. A histologic section of connective tissue shows numerous cells containing large numbers of uniformly sized basophilic granules. The cells are ovoid, with a centrally located nucleus, and are aligned along blood vessels. The cells are most likely

A. plasma cells B. macrophages C. eosinophils D. mast cells E. fibroblasts

A

D. mast cells

24
Q
  1. Which is NOT a cross-banded collagen?

A. collagen I

B. collagen II

C. collagen III

D. collagen IV

E. all of the above are cross-banded collagens

A

D. collagen IV

25
Q
  1. Which of the following pairs is MISMATCHED?

A. macrophages – phagocytic cells that present antigens to T lymphocytes

B. multilocular adipocytes – function to generate heat

C. neutrophil – bilobed nucleus, specific cytoplasmic granules with antiparasitic proteins

D. mesenchymal cell – stellate cell of embryonic mesoderm; precursor of most of fixed cells of connective tissues

E. basophil or mast cell – heparin and histamine

A

C. neutrophil – bilobed nucleus, specific cytoplasmic granules with antiparasitic proteins

26
Q
  1. Which of the following does NOT synthesize collagen?

A. fibroblast B. chondrocyte C. osteoblast D. macrophage E. Schwann cell

A

D. macrophage

27
Q
  1. Sulfation of sugars in proteoglycans occurs in which of the following cell structures?

A. Golgi

B. Peroxisomes

C. Late endosomes

D. Rough endoplasmic reticulum (rER)

E. Smooth endoplasmic reticulum (sER)

A

A. Golgi

28
Q
  1. Which of the following statements accurately describes tropocollagen?

A. It is an aggregate of collagen fibrils forming large banded fibers

B. It is the basic molecule from which collagen fibrils self assemble

C. It is the precursor polypeptide of procollagen

D. It can be recognized in electron micrographs by its 64 - 68 nm axial periodicity

E. It is polymerized into collagen fibrils in the Golgi apparatus

A

B. It is the basic molecule from which collagen fibrils self assemble

29
Q
  1. Which cells are primarily responsible for the synthesis of extracellular matrix components in adult loose connective tissue?

A. Adipocytes B. Fibroblasts C. Macrophages D. Mesenchymal cells E. Myofibroblasts

A

B. Fibroblasts

30
Q
  1. The banded structure shown in the diagram above represents one:

A. Collagen type I fibril

B. Collagen type II fiber

C. Collagen type IV fibril

D. Tonofilament

E. Tropocollagen molecule

A

A. Collagen type I fibril

Histo Exam 1 (5 decks)

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