Written Exam One Q121 - Q150 Flashcards

1
Q
121. The A band of striated muscle:
A. is bisected by the Z line (band)
B. contains both thick and thin filaments
C. decreases in size during contraction
D. is isotropic
A

B. contains both thick and thin filaments

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2
Q
  1. Cardiac myocytes:
    A. branch
    B. contain peripherally positioned nuclei
    C. have a T-tubule system identical to that seen in skeletal muscle
    D. are connected by intercalated disks
    E. both “A” and “D”
A

E. both “A” and “D”

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3
Q
  1. In skeletal muscle:
    A. Z lines (bands) are located at A-I junctions
    B. nuclei are multiple and centrally located
    C. calcium is stored in sER during relaxation
    D. intercalated disks join adjacent fibers end to end
    E. mitochondria are much more numerous than in cardiac muscle
A

C. calcium is stored in sER during relaxation

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4
Q
124. In a sarcomere of skeletal muscle, which molecule or molecular aggregate connects Z disk to M line?
A. actin
B. myosin
C. nebulin
D. titin
E. tropomyosin
A

D. titin

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5
Q
125. Which of the following is NOT found in smooth muscle?
A. alpha-actinin
B. thin filaments
C. triads
D. thick filaments
E. centrally located nuclei
A

C. triads

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6
Q
  1. Unmyelinated axons in the peripheral nervous system:
    A. have no special glial investment
    B. are immediately surrounded by an endoneurium
    C. are infrequent
    D. occupy troughs in the cytoplasm of Schwann cells
    E. do none of the above
A

D. occupy troughs in the cytoplasm of Schwann cells

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7
Q
  1. In axons and dendrites, kinesin functions:
    A. to transport synaptic vesicles from the soma to presynaptic terminals
    B. to move mitochondria from synaptic terminals back to the soma
    C. in retrograde fast axonal transport
    D. both “A” and “B”
    E. both “B” and “C”
A

A. to transport synaptic vesicles from the soma to presynaptic terminals

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8
Q
128. The neurons of the dorsal root (sensory) ganglia are \_\_\_\_\_\_\_\_\_\_ in form.
A. unipolar
B. pseudounipolar
C. bipolar
D. multipolar
E. both "A" and "B"
A

B. pseudounipolar

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9
Q
129. Collagen fibrils with 64-68 nm cross-banding are visible adjacent to Schwann cells in a TEM of peripheral nerve tissue. The collagen is part of the:
A. basal (external) lamina
B. endoneurium
C. perineurium
D. epineurium
E. deep fascia
A

B. endoneurium

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10
Q
130. In a histologic section of spinal cord, rows of nuclei are seen aligned between myelinated axons in the white matter. The observed nuclei are evidence of which cell type?
A. pseudounipolar neurons
B. satellite cells
C. oligodendrocytes
D. Schwann cells
E. multipolar neurons
A

C. oligodendrocytes

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11
Q
131. Positive identification of the central or peripheral nervous system source of a myelinated axon in a TEM can be based on the presence or absence of:
A. basal (external) laminae
B. major & minor dense lines
C. Nissl substance
D. incisures of Schmidt-Lantermann
E. nodes of Ranvier
A

A. basal (external) laminae

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12
Q
132. The endothelium of capillaries in cardiac muscle have all of the following EXCEPT:
A. a basal lamina
B. fenestrations
C. rER
D. tight junctions
E. plasmalemmal vesicles
A

B. fenestrations

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13
Q
  1. When comparing lymphatics and veins, which of the following features would be seen ONLY in lymphatics and not in veins?
    A. presence of valves
    B. a continuous endothelium
    C. a distinct three-layered wall with the t. externa as the most prominent
    layer
    D. only lymphocytes and tissue fluid in the lumen
    E. both “A” and “D”
A

D. only lymphocytes and tissue fluid in the lumen

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14
Q
  1. Which of the following features enable one to distinguish veins from arteries?
    A. presence of a fenestrated endothelium
    B. smooth muscle in the tunica media
    C. a tunica externa that forms the most prominent layer
    D. presence of valves
    E. both “C” and “D”
A

E. both “C” and “D”

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15
Q
  1. Endothelial cell intercellular junctions include:
    A. tight junctions
    B. occasional desmosomes with tonofilaments
    C. zonula occludens
    D. all of the above
A

D. all of the above

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16
Q
136. Arterioles:
A. regulate blood flow to capillary beds
B. have a continuous endothelium
C. contain only a few layers of smooth muscle in the t. media
D. all of the above
E. only "A" and "C"
A

D. all of the above

17
Q
  1. The cardiac skeleton functions to:
    A. support the tricuspid, mitral, aortic and pulmonic valves
    B. electrically insulate the atria from the ventricles
    C. provide an origin for “nested baskets” of cardiac myocytes as they encircle the heart chambers
    D. all of the above
    E. none of the above
A

D. all of the above

18
Q
  1. The tissue forming the impulse-generating and impulse-conduction
    system of the heart consists of modified:
    A. motor neurons
    B. collagen fibers
    C. myelinated axons
    D. smooth muscle
    E. cardiac myocytes
A

E. cardiac myocytes

19
Q
139. One tissue listed below forms a continuum throughout the
cardiovascular system. Which one?
A. smooth muscle
B. stratified cuboidal epithelium
C. Purkinje fibers
D. simple squamous epithelium
E. cardiac myocytes
A

D. simple squamous epithelium

20
Q
140. Purkinje fibers are most obvious in histologic sections of which of the following?
A. AV node
B. epicardium of the ventricles
C. interventricular septum
D. myocardium of the atria
E. SA node
A

C. interventricular septum

21
Q
141. A blood vessel 2 mm in diameter that, on histologic examination, is seen to have a distinct internal elastic lamina and a prominent tunica media is most likely a/an:
A. elastic artery
B. muscular artery
C. arteriole
D. pericytic venule
E. small vein
A

B. muscular artery

22
Q
  1. White pulp of spleen:
    A. contains periarterial lymphatic sheaths (PALS)
    B. filters lymph from afferent lymph vessels
    C. contains T-cell-rich lymphoid nodules
    D. shows a cortico-medullary arrangement
    E. contains splenic (Billroth’s) cords
A

A. contains periarterial lymphatic sheaths (PALS)

23
Q
  1. Hassall’s corpuscles:
    A. occur in both cortex and medulla of the thymus
    B. are epithelial whorls of function that was unknown until 2005
    C. are present in all lymphoid tissues
    D. are formed by mesodermally derived reticular cells
A

B. are epithelial whorls of function that was unknown until 2005

24
Q
  1. Which of the following occurs or resides within the paracortex (deep cortex) of lymph nodes?
    A. HEVs
    B. T cell area
    C. macrophages
    D. dendritic cells (interdigitating dendritic cells)
    E. All of the above
A

E. All of the above

25
Q
  1. “Class switching” refers to:
    A. production of IgM during the initial humoral immune response
    B. production of an immunoglobulin other than IgM during the later stages of a humoral immune response.
    C. an alteration between surface expression of MHC class I or MHC class II on the plasma membrane of APCs.
    D. alternate expression of immunoglobulin light chains (either k or l chains) along with the same heavy chain
A

B. production of an immunoglobulin other than IgM during the later stages of a humoral immune response.

26
Q
  1. Which of the following is NOT a feature shared by TCRs and BCRs?
    A. antigen binding by variable domains
    B. specificity of antigen binding results from DNA rearrangements of the receptor genes in the absence of antigen (i.e., antigen does not direct the DNA recombinations)
    C. antigen binding domain created by sites located on more than a single polypeptide chain
    D. affinity maturation in secondary lymphoid tissues generates receptors with better and better binding affinities for the antigen
    E. transmembrane domains anchor the receptor to the surface of the plasma membrane
A

D. affinity maturation in secondary lymphoid tissues generates receptors with better and better binding affinities for the antigen

27
Q
147. Aggregated lymphoid nodules form (in) which of the following?
A. thymus
B. Peyer's patches
C. appendix
D. All of the above
E. only "B" and "C" above
A

E. only “B” and “C” above

28
Q
  1. At which point in the vasculature of a lymph node would a B lymphocyte leave the blood stream to enter the lymphatic tissue of the node?
    A. capillaries of the superficial (nodular) cortex
    B. venules of the deep (non-nodular) cortex
    C. capillaries of the superficial medulla
    D. venules of the deep medulla
A

B. venules of the deep (non-nodular) cortex

29
Q
149. The predominant cell type found in a germinal center is a:
A. macrophage
B. T lymphocyte
C. reticular cell
D. B lymphocyte
E. plasma cell
A

D. B lymphocyte

30
Q
150. Surgical removal of the thymus from a neonate would result in drastically depleted numbers of which of the following cell types?
A. B cells
B. Mast cells
C. T cells
D. plasma cells
A

C. T cells