Wound Management

Question 1

What two particular properties are attributed to vacuum-assisted wound closure?

Answer 1

• Removal of fluid: reducing interstitial pressure, allowing vascular beds to expand, grow (vascular endothelial growth factor) and perfuse tissue. Allows endothelial membrane regeneration.
• Viscoelastic flow (Mechanical deformation): promotes the production of Fibroblast Growth Factor-2 (distraction histogenesis), which promotes increased mitotic rate.