Wound Healing II Flashcards
second intention healing is best used for wounds that have _________
wounds over joint, adequate vascular supply, mobile skin to allow contraction
often found growing on granulation tissue, but just as a surface contaminant and doesn’t need to be treated
pseudomonas
exuberant granulation tissue is primarily composed of ______
fibroblasts, capillaries
poor imobilization of distal limb wounds left to heal by 2nd intention can cause ______
exuberant granulation tissue
tx for excess granulation tissue
sx, corticosteroids, equine amnion, chemical debridement (white’s lotion, meat tenderizer)
dressing that retains wound exudate and prevents opportunistic bacterial infections; impermeable so decrease O2 tension
occlusive
dressing that allows wounds to drain and breath
non occlusive
bandage best for wounds over joints and tendions, but may be used over open wounds; decreases incidence of exuberant granulation tissue
cast immoblization
indicated when defect is greater than the ability to epithelialize such as large lower limb wounds or defects under neoplasm
skin graft
acceptance of a tissue graft is entirely based on __________ within the graft
ability to establish arterial and venous network
blood/serum accumulation under graft and insufficient immobilization prevent _______, leading to graft failure
revascularization
causes graft failure by slowing cell migration, destroying cells and destroying fibrin film
bacterial infection
ways to stimulate granulation tissue
hydrotherapy, wet saline bandage, iodine dressing, water soluble abx ointment
characteristics of ideal granulation bed
smooth, slightly convex, immobile, well-attached to skin
free skin graft that requires ideal conditions and leaves a big hole where you take it from, so donor location needs to be able to heal by second intention
full-thickness
