Wound healing and management Flashcards
What is a wound?
The disruption in continuity or the integrity of the surface of body or organ
What are the 6 aetiologies of a wound?
- External violence
- Mechanical stress
- Chemical agents
- Infective agents
- Thermal agents
- Radiation
What are the 3 process of healing?
- Inflammatory phase
- Proliferative phase
- Remodelling phase
What happens during the inflamamtory phase?
- Takes 24-48 hours
- Platelets release cytokines and growth hormones, which causes inflammation
- Fibrin attracts neutrophils
- Macrophages reduce bacteria and debride necrotic tissue, which stimulates angiogenesis (making new blood vessels)
What happens during the proliferative stage?
- Fibroblasts lay down a new matrix and endothelial cells lay down capillaries and epithelial cells
- Granulation tissue is produced
- Wound contraction occurs 5-9 days post injury
- Collagen laid down
What happens during the remodelling phase?
- 7-10 days post injury
- Scar formation
- Tissue heals through resolution (little inflammation and restores back to normal state), regeneration (damaged tissue completely replaced) and organisation (replacement tissue, which is the scar)
What are the different factors impairing wound healing?
- Age
- Medication
- Genetics
- Quality of circulation
- Pre-exisiting conditions
- Diet
- Hydration status
- Stress
What are the 5 classifications of wounds and describe them?
- Closed wound (contusion)
- Clean (no contamination)
- Clean contaminated (minimal contamination)
- Contaminated (Heavily contaminated)
- Dirty (Active infection)
What is a 1st degree contusion?
Bruise rupture of capillaries and sub-cut area
What is a 2nd degree contusion?
Rupture of larger vessels causing an accumulation of blood
What is a 3rd degree contusion?
More extensive tissue damage with possibility of infection; internal organs may be injured
What are the two things wound healing is dependent on?
- Level of contamination
- Viability of wound tissues
What are the 4 methods of wound healing?
- Primary wound closure
- Delayed primary closure
- Second intention healing
- Secondary closure
How is a bacterial infection assessed?
- Tissue biopsy
- Swab samples
How do you intially clean a contaminated wound?
- Cover wound with gel or saline covered swab
- Flush wound with sterile saline, tap water, lactated ringers, 0.05% chlorohexidine, 0.01-1% povidone-iodine
- Take a bacterial swab for culture
- Apply sterile dressing and bandage
What is debridement?
- Removal of a bioburden and foreign material from a wound, which promotes wound healing
- Can happen naturally, which is driven by neutrophils and macrophages