Basic Pharmacology Flashcards

1
Q

What are the 4 legal categories of medicines?

A
  • Prescription only medicine: veterinarian (POM-V)
  • Prescription only medicine: veterinarian, pharmacist, SQP (POM-VPS)
  • Non-food animal: veterinarian, pharmacist, SQP (NFA-VPS)
  • Authorised veterinary medicine: general sales list (AVM-GSL)
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2
Q

What is POM-V?

A

Medicine only prescribed by a veterinary surgeon; a clinical assessment and must be under care to receive

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3
Q

What is POM-VPS?

A

Medicine that can given to an animal that is not under care and has not had a clinical assessment

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4
Q

What is NFA-VPS?

A

Anti-parasiticides that can be given to animals not under care and not have had a clinical assessment

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5
Q

What is AVM-GSL?

A

Any medicine supplied by any retailer without restrictions

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6
Q

What are the controlled drugs (Schedule 1- 5)?

A

S1: LSD
S2: Fentanyl, morphine, and ketamine
S3: Buprenorphine, Pentobarbital
S4: Benzodiazepines, anabolic steroids
S5: Preparations containing codeine or morphine in low concentrations

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7
Q

What does s.i.d mean?

A

Once a day

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8
Q

What does b.i.d mean?

A

Twice a day

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9
Q

What does t.i.d mean?

A

Three times a day

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10
Q

What does q.i.d mean?

A

4 time a day

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11
Q

What does q4h mean?

A

Every 4 hours

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12
Q

What does e.o.d mean?

A

Every other day

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13
Q

What does prn mean?

A

As needed as required

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14
Q

What does p.c mean?

A

after food/meal

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15
Q

What does a.c mean?

A

Before meal/food

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16
Q

What does o.m mean?

A

Every morning and night

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17
Q

What does o.d mean?

A

Every day

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18
Q

What does stat mean?

A

Immediately

19
Q

How is pharmacology managed?

A
  • Ordering and controlling stock
  • Storage
  • Packaging
  • Dispensing and disposing
20
Q

What does nomenclature mean?

A
  • Every drug has up to 3 names
  • Chemical name
  • Generic name
  • Brand name
21
Q

What are the 6 categories of drugs?

A
  • Antimicrobial agents
  • Antibacterial
  • Antifungal
  • Antiviral
  • Anthelmintics
  • Ectoparasiticides
22
Q

What are the 8 types of anti-inflammatory drugs?

A
  • Corticosteroids
  • Nonsteroidal anti-inflammatory
  • Analgesics
  • Sedatives
  • Diuretics
  • Bronchodilators
  • Vaccines
  • Antieileptics
23
Q

What are the 2 types of cardiovascular drugs?

A
  • Myocardial stimulants
  • Anti-dysrhythmics
24
Q

What are the 3 types of vasodilator drugs?

A
  • Arterial dilators
  • Vasodilator
  • Mixed dilator
25
Q

What is pharmokinetics?

A
  • Movement of drugs through the body
26
Q

What are the enteral routes (GIT) for drug administration?

A
  • Per os
  • Suppositories (per rectum)
  • Stomach tubes
  • Feeding tubes
27
Q

What is parenteral adminsitration?

A

Besides, beyond or apart from the intestines

28
Q

What are the 8 different parenteral routes?

A
  • Intravenous
  • Intra-arterial
  • Intramuscular
  • Subcutaneous
  • Intradermal
  • Intraperitoneal
  • Topical
  • Inhalation and nebulisation
29
Q

What is the first pass effect?

A

Drugs that partially or completely broken down by the liver may be excreted into the bile, going straight back to the GI tract

30
Q

What is pharmocodynamics?

A
  • How drugs affect the body
31
Q

How are orally administered drugs absorbed?

A
  • Travel through GIT with most being absorbed in the small intestine, enters hepatic portal circulation and is directed to the liver
  • Solid oral preparations must be dissolved in the GIT before absorption
  • Liquid preparations do not need to be dissolved
32
Q

What is pharmocodynamics?

A

How drugs affect the body or how the body responds to the drug

33
Q

What are the two ways a drug can elicit an effect?

A
  • Receptor-mediated pharmacodynamic
  • Non-receptor-mediated pharmacodynamic
34
Q

What is receptor-mediated pharmacodynamics?

A
  • The drug binds to the active site of receptors in the body, which changes the activity of the cell
  • Some receptors allow the drug in directly, but some require mediators
35
Q

What are the 3 types of receptor site interactions?

A
  • Agonist
  • Antagonist
  • Partial agonist
36
Q

What is an agonist?

A

Drug mimics endogenous ligands and fits into the active site of teh receptor and initiates a response

37
Q

What is an antognist?

A
  • Drug interacts with receptor site and prevents any response, so blocks and depresses the receptor
  • This is called an inhibitor
38
Q

What is a partial agonist?

A

A substance that doesn’t not exactly fir the active site as well as the endogenous ligand, so only a partial effect is initiated.

39
Q

What is non-receptor-mediated pharmacodynamics?

A
  • Drugs exert their effects via receptors
  • Antimicrobials, chemical action and physical action
40
Q

What does TD50 mean?

A

A dose that results in toxicity in 50% of the population

41
Q

What does LD50 mean?

A

The lethal dose in 50% of the population

42
Q

What does the ED50 mean?

A
  • The effective dose in 50% of the population
43
Q

What is the equation for working out a total dose?

A

Animals weight x dosage rate / drug concentration