Wound healing

Question 1

Two phases of inflammation phase?

Answer 1

vascular response

cellular response

Question 2

Cardinal signs of inflammation

Answer 2

edema
redness
warmth
pain
loss of function

Question 3

Key cells in cellular response? (inflammation)

Answer 3

platelets, PMNs, macrophages, mast cells

Question 4

Key cells in proliferation phase?

Answer 4

myofibroblasts, angioblast, fibroblast, keratinocyte

Question 5

3 phases of wound healing?

Answer 5

inflammation- control bleeding, fight infectious agents
proliferation- lay down tissue, pull wound together, migration
Maturation- collagen synthesis. strengthen/reorganize

Question 6

What type of factors can affect wound healing?

Answer 6

general- onset, location
local- circulation, sensation, stress
systemic- age, nutrition, comorbidities, meds
clinician- appropriate vs. inappropriate

Question 7

2 types of wound closure

Answer 7

1. primary- edges approximated w/o formation of granulation tissue (pt doesn’t see)
2. secondary- wound heals by being left open (pt)

Question 8

DIME stands for what?

Answer 8

debridement
infection/inflammation
moisture
edge affect