Wound healing Flashcards

1
Q

What are the steps of wound healing?

A
  1. Hemostasis
  2. Inflammation
  3. Proliferating phase
  4. Maturation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how long does it take for hemostasis to occur

A

seconds to hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How long does it take for Inflammation to occur?

A

Hours to days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How long does it take for the proliferative phase to occur

A

days to weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How long does it take for maturation to occur?

A

months to years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is hemostasis?

A

A process where blood vessels constrict and platelets aggregate to promote blood clotting and stop bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what happens during inflammation (short summary)

A
  • Neutrophils eat debris/ pathogen

- macrophages eat neutrophils with dead debris in them

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what happens during the Proliferative phase

A
  • granulation tissue is formed
  • angiogenesis
  • fibroblasts make new collagen
  • epithelization
  • Myofibroblasts contract wound together
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what do fibroblasts do?

A

they make collagen (need copper to do this)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is angiogenesis

A

formation of new blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is epithelization

A

the replication and migration of epithelial cells to the edges of a wound in response to a growth factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is happening during maturation phase?

A

Collagen 3 is replaced by collagen 1by using metalloproteases (need zinc)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is a metalloprotease?

A

any catalytic enzyme that uses a metal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly