Wound Healing Flashcards
What are the four stages of wound healing
Hemostasis , inflammatory, proliferative, remodeling
What stage of Injury is responsible for stopping the bleeding at the injury site
Hemostasis phase
What are some of the growth factors that the clot and surrounding wound tissue release
Transforming growth factor , platelet derived gf , fibroblast gf , epidermal gf
What are the characteristics of the inflammatory phase
Infiltration of neutrophils, macrophages and lymphocytes
What cells are responsible for cleaning the wonded area
Neutrophils and macrophages
During the inflammatory phase what occurs first
Hemostasis
Function of macrophage
Inducing and clearing apoptic cells
What happens in the remodeling phase
Newly formed collagen matrix is rearranged
Which stage is the longest
Remodeling
Classification of chronic wounds
Vascular ulcers , diabetic ulcer and pressure ulcer
Factors affecting wound healing
Local factors, systemic factors
Contamination?
Colonization
Presence of non- replicating organisms on a wound
Presence of replicating micro organisms on the wound without tissue damage
Delayed wound healing in old people is associated with
Altered inflammatory response
