Workshop One Flashcards
1
Q
What is the units for AUC?
A
mg.h/L
2
Q
What is the equation for bioavailibility?
A
F= ((AUCpo)/(AUCiv)) x ((DOSEiv)/(DOSEpo))
3
Q
What is the equation for volume of distribution?
A
V= Amount of drug in the body / plasma drug concentration
4
Q
What is the equation for loading dose?
A
LD (mg) = V x Target concentration (mg/L)
5
Q
What is the equation for elimination rate?
A
Elimination rate (mg/h) = CL (L/h) x conc. (mg.L)
6
Q
What is the equation for clearance?
A
CL (L/h) = Dose (mg) / AUC (mg.h /L)
7
Q
What is the equation for maintenance dose?
A
MD (mg/h) = CL (L/h) x target Concentration (mg/L)
8
Q
What is the equation for half life?
A
T0.5 = 0.7 x V/CL
