Womens/ STI Flashcards
FSH stimulates eggs into producing estrogen
* ↑ Estrogen, stimulates growth of endometrium
* Around day 14 the woman most fertile
Follicular phase (days 1-14)
LH induces ovulation
Midcycle (day 14): Ovulatory Phase
Helps stabilize endometrial lining
Luteal Phase (days 14-28)
- Estrogen ↓, Progesterone ↓
Menstruation
Safe for breast feeding.
* Should be taken at the same Ame every day.
* Late dose (>3hr) or missed day, use condom.
Proges1n-Only Pills: 9% failure rate “mini pill”
Contraindications for COC
Smoker >35 years old (>15 cigarettes per day)
* History of
* ↑ risk of blood clotting.
* Thromboembolic disorders (DVT): thrombus,
emboli.
* Genetic coagulation defects (factor V Leiden
Disease).
* Prolonged immobility (surgery).
* Inflammation or acute infections of the liver with ↑ LFTs.
* Cardiovascular disease.
* Conditions that increase risk of stroke.
* Migraines, CVAs, TIAs, HTN.
Beneifts of COC (5+ years)
- Decreases risk of ovarian and endometrial
cancers by 40-50%. - ↓ acne, hirsutism.
- Regulates heavy menses, dysmenorrhea,
cramps, ↓ pain with endometriosis. - ↓ risk of ovarian cysts.
What to do if missed 2 days of BC pills?
Missed 2 days of pill: Take 2 pills the next 2 days, use condom.
3-month IM injection.
* Must check for pregnancy before use.
* To be used at least 1 yr. (Not recommended if planning to get pregnant within 12 months)
* Black/Box WARNING: not to be used for more than 3 yrs due to risk bone demineralization
(osteopenia/osteoporosis) .
* Do not use with hx. Anorexia (order DEXA).
* Recommend Vitamin D and Ca, weight bearing exercises.
Depo-Provera
Cause: anaerobe bacterial infec1on in the vagina.
* Risk factors: sexual ac1vity, mul1ple sex partners, douching.
* NOT an STI. Sexual partner does not need to be treated.
* Whiff test: fishy odor.
* Treatment: metronidazole (Flagyl)
* Flagyl educaAon: avoid alcohol.
* Lab findings:
* + Clue cells.
* + Whiff test
Bacterial Vaginosis
Cause: Overgrowth of Candida albicans yeast.
Risk factors: DM, HIV (or any immunosuppression), on abx.
Findings: white cheese-like curd vaginal discharge, severe vulvovaginal
itching, swelling, redness.
Treatment: Miconazole (Monistat), clotrimazole.
Lab findings: Wet Smear Microscopy
* pseudo hyphae and spores w/WBC
Candida Vaginitis
Cause: unicellular protozoan parasite w/ a flagella. Affects male and female. Symptoms include
itching, burning, irritation of vagina/urethra.
Risk factors: multiple sex partners, hx of STI, previous trich, no condom use.
Findings: “strawberry cervix” (punctate hemorrhages), swollen and erythematous vaginal area,
dysuria.
Treatment: Metronidazole (flagyl). Treat sexual partner.
Lab findings: Mobile unicellular organism with flagella, ↑ WBC.
Trichomonas Vaginitis
Cause: chronic lack of estrogen in urogenital tract = atrophic changes in vulva and vagina.
Risk factors: menopause.
Findings: atrophic labia, decreased rugae, fissures, dry, pale vagina.
Treatment: estrogen.
Atrophic Vaginitis
Cause: hormonal changes due to menses, causes painful cysts to enlargein breasts. Cyclical, cysts change size and symptoms vary. Benign.
Risk factors: Common around age 30s. Worst 2 weeks before menses.
Findings: painful/tender mass like growths on one or both breasts that change in size depending on menses cycle.
Treatment: Wear good bra support. Reduce caffeine. Primrose capsules or oil, vitamin E. If cyst continues to bother, may remove fluid to relieve symptoms.
Fibrocystic Breasts
Cause: endocrine disorder in women of reproductive age. Primary
characteristics: hyperandrogenism, anovulation, insulin resistance and
neuroendocrine disruption.
Findings:
* Obesity, facial hair, hyperlipidemia, obstructive sleep apnea, acne,
amenorrhea, infrequent periods. Infertility.
* On transvaginal US: enlarged ovaries with multiple small follicles.
* Elevated hormones: testosterone, dehydroepiandrosterone,
androstenedione.
Treatment: contraceptives, spironolactone, metformin, weight loss.
PCOS
Cause: bone demineralization due to estrogen deficiency from menopause.
Risk factors: menopause, anorexia/bulimia, chronic steroid use, long term use PPIs, gastric bypass, celiac
disease, hyperthyroidism, ankylosis spondylitis, RA, low Ca intake, vitamin D deficiency, inadequate physical
activity, alcoholism, high caffeine intake, smoking.
Findings: older female (>50), being thin, small body frame, family history. White or Asian descent.
Osteoporosis