Renal Flashcards
- Better measure for renal function (blood test).
- Tests kidney function. Renal function decreases, creatinine
increases. - Male 0.7-1.3, female 0.6-1.1. >5.0 in adults = kidney impairment.
- High levels may indicate dehydration, protein intake, creatine
supplements.
Serum Creatinine
When Renal function decreases ______
creatinine increases and creatinine clearance also decreases
Provides information on how well the kidneys are working.
* Tests proteinuria, albuminuria, microalbuminuria. Renal function decreases, Creatinine clearance also decreases. Reflects renal function
for the past 24 hrs.
Creatinine Clearance (24 hr. urine)
Used to evaluate for kidney disease and stage. Measures the kidney’s
ability to filter toxins and waste from the blood.
* Ranges: >90 mL/min. Renal failure stage 5 if <15 mL/min.
Estimated Glomerular Filtration Rate (eGFR)
Reveals information on how well the kidneys are working, measures kidney’s ability to excrete urea.
* High levels: acute renal failure, high protein diet, hemolysis, CHF, drugs.
Normal ranges 6-24 mg/dL.
Blood Urea Nitrogen
High BUN with normal eGFR =
renal function probably normal
High BUN with low GFR =
higher mortality
Used to evaluate dehydration, hypovolemia, acute renal failure and level of renal failure. used in chemo to evaluate stress on the kidneys
BUN-to-Creatinine Ratio
- Color: yellow, light/pale, amber, red.
- Clarity/turbidity- clear or cloudy
- pH: 4.5-8
- Specific gravity: 1.005-1.025
- Glucose: ≥130 mg/d
- Ketones
- Nitrates
- Leukocyte esterase
UA
WBC casts with proteinuria is observed in _______.
pyelonephritis
+ Nitrites in UTI indicates
Ecoli Infection
What if leukocytes seen in male urine
tx for infection
Protein in the urine…
kidney damage, pyelonephritis.
Presence of bacteria (urine culture growth of 100,000 CFU/mL or more) in the urine without
symptoms of UTI.
* Due to increasing antimicrobial resistance, DO NOT treat.
* Always treat pregnant woman with antibiotics.
Asymptomatic Bacteriuria
(leukocytosis, fever, chills, malaise) is treated as a UTI.
- Symptomatic bacteriuria