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Pharm > Women's Health Med Review > Flashcards

Women's Health Med Review Flashcards

1
Q

Estradiol Trade Name

A

Estrace (oral)

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2
Q

Estradiol Category

A

Oral Estrogen Derivative

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3
Q

Estradiol Use

A

Menopause

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4
Q

Estradiol Dose

A

0.5-1 mg PO qday

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5
Q

Estradiol AE

A

Common: Nausea, headache, bloating, breast tenderness, bleeding

Serious: CHD, stroke, VTE, breast CA, gallbladder disease

CI: Hx of/active thromboembolic disease; breast cancer or estrogen-dependent neoplasm; pregnancy; liver disease, undiagnosed vaginal bleeding; prevention of treatment of cardiovascular disease, cerebrovascular disease, or dementia

Preg Cat: X

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6
Q

Medroxyprogesterone Acetate (MPA) Trade Name

A

Provera

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7
Q

Medroxyprogesterone Acetate Category

A

Oral Progestrogen; Contraceptive

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8
Q

Medroxyprogesterone Acetate Use

A

Menopause

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9
Q

Medroxyprogesterone Acetate Dose

A

2.5-10 mg PO qday

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10
Q

Medroxyprogesterone Acetate AE

A

Common: nausea, headache, weight gain, bleeding, irritability, depression

Serious: VTE, decreased BMD; may cause increased risk of breast cancer when used continuously with estrogen

CI: Hx of/active thromboembolic disease; breast cancer or estrogen-dependent neoplasm; pregnancy; liver disease, undiagnosed vaginal bleeding; prevention of treatment of cardiovascular disease, cerebrovascular disease, or dementia

Preg Cat: X

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11
Q

Estradiol Transdermal Trade Name

A

Alora, Climara, Estraderm, Vivelle, Vivelle Dot

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12
Q

Estradiol Transdermal Category

A

Transdermal estrogen

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13
Q

Estradiol Transdermal Use

A

Menopause

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14
Q

Estradiol Transdermal Dose

A

0.025-0.05 mg patch, changed weekly (Climara) or changed twice weekly

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15
Q

Estradiol Transdermal AE

A

Common: Nausea, headache, bloating, breast tenderness, bleeding

Serious: CHD, stroke, VTE, breast CA, gallbladder disease

CI: Hx of/active thromboembolic disease; breast cancer or estrogen-dependent neoplasm; pregnancy; liver disease, undiagnosed vaginal bleeding; prevention of treatment of cardiovascular disease, cerebrovascular disease, or dementia

Preg Cat: X

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16
Q

Estradiol + Norethidrone Transdermal Trade Name

A

CombiPatch

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17
Q

Estradiol + Norethidrone Transdermal Category

A

Combination Transdermal Estrogen/Progestogen

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18
Q

Estradiol + Norethidrone Transdermal Use

A

Menopause

19
Q

Estradiol + Norethidrone Transdermal Dose

A

0.05/0.14 - 0.05/0.25 mg per 24 hours; apply one patch twice weekly

20
Q

Estradiol + Norethidrone Transdermal AE

A

ESTROGEN:
Common: Nausea, headache, bloating, breast tenderness, bleeding

Serious: CHD, stroke, VTE, breast CA, gallbladder disease

PROGESTOGEN:
Common: nausea, headache, weight gain, bleeding, irritability, depression

Serious: VTE, decreased BMD; may cause increased risk of breast cancer when used continuously with estrogen

CONTRAINDICATIONS:
Hx of/active thromboembolic disease; breast cancer or estrogen-dependent neoplasm; pregnancy; liver disease, undiagnosed vaginal bleeding; prevention of treatment of cardiovascular disease, cerebrovascular disease, or dementia

Preg Cat: X

21
Q

Norgestimate/Ethinyl Estradiol (EE) Trade Name

A

Sprintec

22
Q

Norgestimate/Ethinyl Estradiol Category

A

Combination Oral Contraceptive (COC); Monophasic w/IM estrogen

23
Q

Norgestimate/Ethinyl Estradiol Use

A

Contraception

24
Q

Norgestimate/Ethinyl Estradiol Dose

A

0.25mg/35mcg PO qday

25
Q

Norgestimate/Ethinyl Estradiol AE

A

AE: Increased risk thromboembolism and stroke; may elevate BP; estrogenic and progestin side effects (nausea, breast tenderness, melasma, headache, breakthrough bleding, increased spotting, hypomenorrhea, fatigue, mood changes, increased appetite, weight gain, acne, oily skin, hirsutism, increased LDL, decreased HDL)

CI:
Absolute: Hx thromboembolic disease, stroke, CAD, breast cancer, estrogen-dependent neoplasm; undiagnosed abnormal uterine bleeding, hepatic tumors; pregnancy; heavy smokers >15 cigs/day over age 35; active liver disease; migraine HA with focal neuro sxs; postpartum during first 21 days as well as days 21-42 in women with additional TE risk factors

26
Q

Raloxifene Trade Name

A

Evista

27
Q

Raloxifine Category

A

2nd Generation Mixed Estrogen Agonist/Antagonist (MEAA)

28
Q

Raloxifine Use

A

Post-menopausal Osteoporosis (60mg PO qday)

29
Q

Raloxifine AE

A

Generally well tolerated; may cause leg cramps and hot flushes; risk for VTE similar to estrogens

30
Q

Alendronate Trade Name

A

Fosomax

31
Q

Alendronate Category

A

Bisphosphonate

32
Q

Alendronate Use

A

Prevention of post-menopausal (PM) osteoporosis; Osteoporosis; Glucocorticoid-induced osteoporosis

33
Q

Alendronate Dose

A

Prevention of PM osteoporosis: 5mg PO qday or 35mg PO qweek (Take after an overnight fast with a full glass of water while sitting or standing upright at least 30 minutes prior to morning meal; do not lie down for 30 minutes after administration; do not take with other meds or fluids; do not chew or suck on the tablet.)

Osteoporosis: 10mg PO qday or 70mg PO qweek

Steroid-induced: 10mg PO qday

34
Q

Alendronate AE

A

AE: Nausea; heartburn; GI pain; irritation; perforation; ulceration and/or bleeding; transient flu-like illness; muscle pains; possible risk of atypical femur fracture; possible slight increase in esophageal cancer; black box warning for rare osteonecrosis of the jaw; unproven risk of Afib.

**Avoid when CrCl <35mL/min

35
Q

Calcium Carbonate Trade Name

A

Tums, Os-Cal, Caltrate, One-A-Day Women’s MVI, Rolaids, Viactiv

36
Q

Calcium Carbonate Category

A

Calcium supplement

37
Q

Calcium Carbonate Use

A

Osteoporosis

38
Q

Calcium Carbonate Dose

A

1200-1500 mg PO qday elemental calcium divided into 500-600 mg doses during or after meals low in fiber to increase absorption

39
Q

Calcium Carbonate AE

A

AE: constipation; GI irritation; flatulance; rare kidney stones; increased Ca++

40
Q

Calcitonin Trade Name

A

Miacalcin

41
Q

Calcitonin Category

A

Calcitonin

42
Q

Calcitonin Use

A

PM Osteoporosis; Useful for painful compression fractures; Decrease corticosteriod-induced osteoporosis

43
Q

Calcitonin Dose

A

200 IU intranasal qday (nasal spray); Alternate nostrils on a daily basis

44
Q

Calcitonin AE

A

AE: May cause rhinitis, epistaxis, local irritation

Pharm (9 decks)

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