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Pharm > Unit I Med Review > Flashcards

Unit I Med Review Flashcards

1
Q

Trade name for Acetaminophen

A

Tylenol

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2
Q

Trade name for Ibuprofen

A

Motrin, Advil

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3
Q

Trade name for Celecoxib

A

Celebrex

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4
Q

Trade name for Oxycodone/APAP

A

Percocet

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5
Q

Trade name for Tramadol

A

Ultram

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6
Q

Trade name for Naloxone

A

Narcan

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7
Q

Trade name for Methotrexate

A

Rheumatrex, Trexall

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8
Q

Trade name for Hydroxychloroquine

A

Plaquenil

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9
Q

Trade name for Etenercept

A

Enbrel

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10
Q

Acetaminophen Category

A

Non-opioid analgesic

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11
Q

Acetaminophen Use

A

Mild-moderate pain; fever

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12
Q

Acetaminophen Dose

A

325-650mg PO q4-6hr

Max: 4000mg/day

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13
Q

Acetaminophen AE

A

Well tolerated; Hepatotoxicity, nephrotoxicity, anemia, blood dyscrasias, rare skin rxns, overdose->severe or fatal hepatotoxicity
CI: severe liver disease or hepatic impairment
Preg Cat: C

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14
Q

Ibuprofen Category

A

Nonselective NSAID

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15
Q

Ibuprofen Use

A

Mild-moderate pain

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16
Q

Ibuprofen Dose

A

200-400mg PO q4-6hr (Max: 3200mg/day)

400-800mg IV q6hr (Max: 3200mg/day)?

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17
Q

Ibuprofen AE

A

GI; renal; antiplatelet; CV; hepatic; CNS (sedation); skin (SJ/TEN)
CI: pts w/angioedema and bronchospasm w/ASA or other NSAID, severe hepatic impairment, CABG
Preg Cat: C; D > 30wks gestation

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18
Q

Celecoxib Category

A

Selective COX-2 Inhibitor

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19
Q

Celecoxib Use

A

Mild-moderate pain

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20
Q

Celecoxib Dose

A

OA: 100mg PO bid or 200mg PO qday
RA: 100-200mg PO big

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21
Q

Celecoxib AE

A

GI (< than N-NSAID); potential increased risk of CV events; renal; hepatic; CNS, skin [NO antiplatelet effect]
CI: sulfa allergy; ASA or NSAID allergy; 3rd trimester pregnancy, CABG
Preg Cat: C; D > 30wks gestation

22
Q

Oxycodone/APAP Category

A

Opioid: u Agonist (related to Morphine)

23
Q

Oxycodone/APAP Use

A

Moderate pain

24
Q

Oxycodone/APAP Dose

A

5/325mg: 1-2 tabs PO q4-6hrs

25
Q

Oxycodone/APAP AE

A

Drowsiness; nausea; vomiting; constipation; decreased respiratory rate; pruritus; tolerance; dependence; CYP3A4 substrate: BBW-toxicity
Preg Cat: C

26
Q

Tramadol Category

A

Opoid: other opioid agonist

27
Q

Tramadol Use

A

Moderate-Severe pain

28
Q

Tramadol Dose

A

50-100mg PO q4-6hrs

Max: 400mg/day

29
Q

Tramadol AE

A

Drowsiness; nausea; vomiting; constipation; decreased respiratory rate; pruritus; tolerance; dependence; Risk for dependence/addiction, seizures, death due to OD/suicide, CYP3A4 substrate
Preg Cat: C

30
Q

Naloxone Category

A

Antidote; u Opioid Antagonist

31
Q

Naloxone Use

A

Opoid OD; Reverse respiratory distress

32
Q

Naloxone Dose

A

Resp Distress: 0.04-0.4mg IV (May Repeat q2-3min)

OD: 2mg IV

33
Q

Naloxone AE

A

Related to reversing dependency and precipitating withdrawal: CV, CNS, GI, diaphoresis, hot flashes, shivering, yawning, etc
Preg Cat: C

34
Q

Methotrexate Category

A

Non-Biologic DMARD

35
Q

Methotrexate Use

A

RA: more active or severe

36
Q

Methotrexate Dose

A

Oral: 7.5-20mg/week
Injectable: 7.5-20mg/wk
Monitor: LFTs and CBC q8wks

37
Q

Methotrexate AE

A

Stomatitis; N/D; alopecia; increased LFTs; low liver toxicity risk; thrombocytopenia; leukopenia; rare pulmonary and lymphoproliferative toxicity.
Caffeine >180mg/day may decrease the effectiveness of MTX for RA
Drug Intx: PPI, NSAIDs, and ASA may decrease renal clearance
Toxicities: Myelosuppression, cirrhosis, hepatic fibrosis, pulmonary infiltrates or fibrosis
CI: liver disease, kidney impairment, lung disease, ETOH abuse, pregnancy and lactation
Preg Cat: X

38
Q

Methotrexate Notes

A

Take w/Folic Acid 5mg/wk to decrease AE

39
Q

Hydroxychloroquine Category

A

Non-Biologic DMARD

40
Q

Hydroxychloroquine Use

A

Less active or milder RA

41
Q

Hydroxychloroquine AE

A

Rash; diarrhea; abdominal cramps; infrequently increased risk renal toxicity if dose >6gm/kg
Toxicity: macular damage (periodic opthalmic exams to check)

42
Q

Etenercept Category

A

Biologic DMARD (TNF Alpha Inhibitor)

43
Q

Etanercept Use

A

RA

44
Q

Etanercept AE

A

May exacerbate or cause CHF; increased risk of infections and lymphomas (Use caution in pts w/HF)

45
Q

Hydroxychloroquine Notes

A

No monitoring required

46
Q

Prednisone Category

A

Corticosteroid

47
Q

Prednisone Use

A

RA, OA, MS pain

48
Q

Prednisone Dose

A

RA: <7.5mg PO qday

49
Q

Prednisone AE

A

Osteoporosis; HTN; hyperglycemia; cataracts; skin fragility; fluid retention; weight gain

50
Q

Prednisone Notes

A

Take 1500mg elemental calcium per day and 400-800IU Vit D per day to prevent/decrease the risk of osteoporosis when taking Prednisone

Pharm (9 decks)

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