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Pharm > Unit II Med Review > Flashcards

Unit II Med Review Flashcards

1
Q

Ceftriaxone Trade Name

A

Rocephin

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2
Q

Ceftriaxone Category

A

3rd Generation Cephalosporin (Abx)

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3
Q

Ceftriaxone Use

A

Meningitis

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4
Q

Ceftriaxone Dose

A

2gm IV q12-24hrs x7-14 days

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5
Q

Ceftriaxone AE

A

Generally well tolerated. Diarrhea, neutropenia, thrombocytopenia, platelet dysfunction, hypersensitivity (Cross reactivity w/PCN 5-10%), SJS, TEN, ISR.

CI: Hypersensitivity to any Cephalosporin; Type I rxn to any PCN; Neonates w/increased bilirubin secondary to kernicterus risk; hepatic/renal impairment; seizure d/o

Preg Cat: B

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6
Q

Rifampin Trade Name

A

Rifadin

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7
Q

Rifampin Category

A

Misc Abx (Anti-TB)

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8
Q

Rifampin Use

A

Meningitis Prophylaxis

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9
Q

Rifampin Dose

A

H.flu: 600mg PO q24h x 4 days

N. meningitidis: 600mg PO q12h x 4 doses

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10
Q

Rifampin AE

A

Rash, cramps, N/V/D, increased LFTs, edema, flushing, ataxia, confusion, fatigue, fever, HA, thrombocytopenia, jaundice, myalgias, flu-like sxs, agranulocytosis, disseminated intravascular coagulation, hepatitis, hepatotoxicity, anaphylaxis, nephrotoxicity, renal failure

Preg Cat: C

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11
Q

Vancomycin Trade Name

A

Vancocin

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12
Q

Vancomycin Category

A

Abx

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13
Q

Vancomycin Use

A

Meningitis

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14
Q

Vancomycin Dose

A

15mg/kg IV q8-12h

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15
Q

Vancomycin AE

A

Hypokalemia, abdominal pain, N/V/D, cardiac arrest, hypoTN, C-diff diarrhea, agranulocytosis, neutropenia, ototoxicity, nephrotoxicity, anaphylaxis, thrombocytopenia

Preg Cat: B/C

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16
Q

Lorazepam Trade Name

A

Ativan (NOTE: Controlled substance - IV)

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17
Q

Lorazepam Category

A

AED: Benzodiazepime

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18
Q

Lorazepam Use

A

Seizure D/O; Status Epilepticus

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19
Q

Lorazepam Dose

A

4mg IV (slow); MR in 5min if no response. Max dose 8mg

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20
Q

Lorazepam AE

A

Sedation, ataxia, confusion (esp older adults), potential for dependence and abuse

CI: acute narrow angle glaucoma, sleep apnea, severe respiratory insufficiency

Preg Cat: D

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21
Q

Topiramate Trade Name

A

Topamax

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22
Q

Topiramate Category

A

AED

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23
Q

Topiramate Use

A

Seizure D/O

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24
Q

Topiramate AE

A

Slowed thinking, speech difficulties, decreased appetitie, decreased cognition, HA, diplopia

Preg Cat: D

CYP substrate and Inducer

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25
Q

Valproic Acid Trade Name

A

Depakote

26
Q

Valproic Acid Category

A

AED

27
Q

Valproic Acid Use

A

Seizure D/O

28
Q

Valproic Acid Dose

A

1000-3000mg qday

Take w/food to decrease GI AE

29
Q

Valproic Acid AE

A

N/V, tremor, ataxia, sedation, weight gain, hepatic failure (esp kids on >1 AED), thrombocytopenia (w/high levels)

Preg Cat: D

CYP Inhibitor
Highly Protein Bound

30
Q

Donepezil Trade Name

A

Aricept

31
Q

Donepezil Category

A

Choinesterase Inhibitor

32
Q

Donepezil Use

A

Alzheimer’s Disease

33
Q

Donepezil Dose

A

5-10mg qday (in am or at hs)

34
Q

Donepezil AE

A

Nausea, vomiting, diarrhea, anorexia, weight loss, bradycardia, cholinergic effects

Preg Cat: C

35
Q

Levodopa/Carbidopa Trade Name

A

Sinemet

36
Q

Levodopa/Carbidopa Category

A

Dopamine Enhancer

37
Q

Levodopa/Carbidopa Use

A

Parkinson’s Disease

38
Q

Levodopa/Carbidopa AE

A

Agitation, confusion, insomnia, psychosis, HA, dizziness, orthostasis, dyskinesias, N/V, hypoTN

Preg Cat: C

39
Q

Interferon B-1a Trade Name

A

Rebif

40
Q

Interferon B-1a (Rebif) Category

A

Interferon B-1a

41
Q

Interferon B-1a (Rebif) Use

A

Multiple Sclerosis

42
Q

Interferon B-1a (Rebif) AE

A

Depression, HA, flu-like symptoms, ISR

Preg Cat: C

43
Q

Sumatriptan Trade Name

A

Imitrex

44
Q

Sumatriptan Category

A

5HT 1b/1d Receptor Agonist

45
Q

Sumatriptan Use

A

Moderate-Severe Migraines

46
Q

Sumatriptan Dose

A

SQ: 6mg SQ x1, MR after 1 hr, Max 12mg/24hr
PO: 25mg PO x1, MR after 2 hr, Max 200mg/24hr
Nasal: 5-20mg nasal x1, MR after 2hr, Max 40mg/24h

Take as soon as symptoms appear!

47
Q

Sumatriptan AE

A

Dizziness, sensation of warmth, chest fullness and nausea MC, angina, arrhythmias, cerebral and myocardial ischemia (rare)

CI: CV disease, angina, h/o MI, uncontrolled HTN, CVA, PVD, hemiplegic and basilar migraine; Do NOT use within 14 days of MAOI or within 24 hours of ergotamine, DHE or methysergide; Do NOT use Ergot derivatives within 6 hrs of sumatriptan

Preg Cat: C

48
Q

Amitriptyline Trade Name

A

Elavil

49
Q

Amitiptyline Category

A

TCA (Tricyclic Antidepressant)

50
Q

Amitriptyline Use

A

Migraine Prophylaxis

51
Q

Amitriptyline Dose

A

30-150mg PO qhs

52
Q

Amitriptyline AE

A

Drowsiness, weight gain, anticholinergic effects

CI: urinary retention, heart block, recent MI, MAOI use in last 14 days

Caution: Serotonin syndrome possible w/triptans

Preg Cat: C

53
Q

Travoprost Trade Name

A

Travatan

54
Q

Travoprost Category

A

Prostaglandin Analog

55
Q

Travoprost Use

A

Glaucoma

56
Q

Travoprost AE

A

Common: Increased iris pigmentation, growth of eye lashes, itching (15-45%)
Less common: dryness, visual disturbance, burning, eye pain, increased pigment of skin at eye

Preg Cat: C

57
Q

Timolol Trade Name

A

Timoptic

58
Q

Timolol Category

A

Beta-Blocker (Non-selective)

59
Q

Timolol Use

A

Glaucoma

60
Q

Timolol AE

A

Local: stinging, dry eyes, corneal anesthesia, blepharitis, blurred vision
Systemic: decreased HR, decreased BP, bronchospasm, masked sxs of hypoglycemia, CNS sedation [One drop in each eye=10mg orally]

CI: asthma, heart block, unstable HF, COPD, bradycardia

Preg. Cat: C

Pharm (9 decks)

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