Unit II Med Review Flashcards by Becky Reimann

Ceftriaxone Trade Name

Rocephin

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Ceftriaxone Category

3rd Generation Cephalosporin (Abx)

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Ceftriaxone Use

Meningitis

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Ceftriaxone Dose

2gm IV q12-24hrs x7-14 days

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Ceftriaxone AE

Generally well tolerated. Diarrhea, neutropenia, thrombocytopenia, platelet dysfunction, hypersensitivity (Cross reactivity w/PCN 5-10%), SJS, TEN, ISR.

CI: Hypersensitivity to any Cephalosporin; Type I rxn to any PCN; Neonates w/increased bilirubin secondary to kernicterus risk; hepatic/renal impairment; seizure d/o

Preg Cat: B

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Rifampin Trade Name

Rifadin

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Rifampin Category

Misc Abx (Anti-TB)

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Rifampin Use

Meningitis Prophylaxis

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Rifampin Dose

H.flu: 600mg PO q24h x 4 days

N. meningitidis: 600mg PO q12h x 4 doses

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Rifampin AE

Rash, cramps, N/V/D, increased LFTs, edema, flushing, ataxia, confusion, fatigue, fever, HA, thrombocytopenia, jaundice, myalgias, flu-like sxs, agranulocytosis, disseminated intravascular coagulation, hepatitis, hepatotoxicity, anaphylaxis, nephrotoxicity, renal failure

Preg Cat: C

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Vancomycin Trade Name

Vancocin

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Vancomycin Category

Abx

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Vancomycin Use

Meningitis

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Vancomycin Dose

15mg/kg IV q8-12h

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Vancomycin AE

Hypokalemia, abdominal pain, N/V/D, cardiac arrest, hypoTN, C-diff diarrhea, agranulocytosis, neutropenia, ototoxicity, nephrotoxicity, anaphylaxis, thrombocytopenia

Preg Cat: B/C

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Lorazepam Trade Name

Ativan (NOTE: Controlled substance - IV)

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Lorazepam Category

AED: Benzodiazepime

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Lorazepam Use

Seizure D/O; Status Epilepticus

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Lorazepam Dose

4mg IV (slow); MR in 5min if no response. Max dose 8mg

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Lorazepam AE

Sedation, ataxia, confusion (esp older adults), potential for dependence and abuse

CI: acute narrow angle glaucoma, sleep apnea, severe respiratory insufficiency

Preg Cat: D

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Topiramate Trade Name

Topamax

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Topiramate Category

AED

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Topiramate Use

Seizure D/O

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Topiramate AE

Slowed thinking, speech difficulties, decreased appetitie, decreased cognition, HA, diplopia

Preg Cat: D

CYP substrate and Inducer

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Valproic Acid Trade Name

Depakote

Valproic Acid Category

AED

Valproic Acid Use

Seizure D/O

Valproic Acid Dose

1000-3000mg qday Take w/food to decrease GI AE

Valproic Acid AE

N/V, tremor, ataxia, sedation, weight gain, hepatic failure (esp kids on >1 AED), thrombocytopenia (w/high levels) Preg Cat: D CYP Inhibitor Highly Protein Bound

Donepezil Trade Name

Aricept

Donepezil Category

Choinesterase Inhibitor

Donepezil Use

Alzheimer's Disease

Donepezil Dose

5-10mg qday (in am or at hs)

Donepezil AE

Nausea, vomiting, diarrhea, anorexia, weight loss, bradycardia, cholinergic effects Preg Cat: C

Levodopa/Carbidopa Trade Name

Sinemet

Levodopa/Carbidopa Category

Dopamine Enhancer

Levodopa/Carbidopa Use

Parkinson's Disease

Levodopa/Carbidopa AE

Agitation, confusion, insomnia, psychosis, HA, dizziness, orthostasis, dyskinesias, N/V, hypoTN Preg Cat: C

Interferon B-1a Trade Name

Rebif

Interferon B-1a (Rebif) Category

Interferon B-1a

Interferon B-1a (Rebif) Use

Multiple Sclerosis

Interferon B-1a (Rebif) AE

Depression, HA, flu-like symptoms, ISR Preg Cat: C

Sumatriptan Trade Name

Imitrex

Sumatriptan Category

5HT 1b/1d Receptor Agonist

Sumatriptan Use

Moderate-Severe Migraines

Sumatriptan Dose

SQ: 6mg SQ x1, MR after 1 hr, Max 12mg/24hr PO: 25mg PO x1, MR after 2 hr, Max 200mg/24hr Nasal: 5-20mg nasal x1, MR after 2hr, Max 40mg/24h Take as soon as symptoms appear!

Sumatriptan AE

Dizziness, sensation of warmth, chest fullness and nausea MC, angina, arrhythmias, cerebral and myocardial ischemia (rare) CI: CV disease, angina, h/o MI, uncontrolled HTN, CVA, PVD, hemiplegic and basilar migraine; Do NOT use within 14 days of MAOI or within 24 hours of ergotamine, DHE or methysergide; Do NOT use Ergot derivatives within 6 hrs of sumatriptan Preg Cat: C

Amitriptyline Trade Name

Elavil

Amitiptyline Category

TCA (Tricyclic Antidepressant)

Amitriptyline Use

Migraine Prophylaxis

Amitriptyline Dose

30-150mg PO qhs

Amitriptyline AE

Drowsiness, weight gain, anticholinergic effects CI: urinary retention, heart block, recent MI, MAOI use in last 14 days Caution: Serotonin syndrome possible w/triptans Preg Cat: C

Travoprost Trade Name

Travatan

Travoprost Category

Prostaglandin Analog

Travoprost Use

Glaucoma

Travoprost AE

Common: Increased iris pigmentation, growth of eye lashes, itching (15-45%) Less common: dryness, visual disturbance, burning, eye pain, increased pigment of skin at eye Preg Cat: C

Timolol Trade Name

Timoptic

Timolol Category

Beta-Blocker (Non-selective)

Timolol Use

Glaucoma

Timolol AE

Local: stinging, dry eyes, corneal anesthesia, blepharitis, blurred vision Systemic: decreased HR, decreased BP, bronchospasm, masked sxs of hypoglycemia, CNS sedation [One drop in each eye=10mg orally] CI: asthma, heart block, unstable HF, COPD, bradycardia Preg. Cat: C