Women's Health Flashcards
COCP mode of action
Inhibits ovulation
Progesterone Only Pill (POP)
Thickens cervical mucous
Desogestrel- only
Primary- inhibits ovulation
Also thickens cervical mucous
Injectable contraceptive (medroxyprogesterone acetate)
Primary: Inhibits ovulation
Also: thickens cervical mucus
Implantable contraceptive (etonogestrel)
Primary: Inhibits ovulation
Also: thickens cervical mucus
Intrauterine contraceptive device
Decreases sperm motility and survival
Intrauterine system (mirena)
Primary: Prevents endometrial proliferation
Also: Thickens cervical mucus
Levonogestrel
Inhibits ovulation
Ulipristal
Inhibits ovulation
IUD as emergency contraception
Toxic to sperm and ovum
What are UKMEC 3
(7 of them!)
> 35 and smoking less than 15 a day
-BMI >35
-Family history of thromboembolic disease in 1st degree relative <45
-Controlled hypertension
-Immobility eg wheelchair use
-Carrier of BRACA-1 or BRACA-2
-Current Gallbladder disease
What are UKMEC 4 conditions?
(9 of them!)
- > 35y/o and smoking >15 a day
-Migraine with aura
-History of thromboembolic disease or thrombogenic mutation
-history of stroke or IHD
-Breast feeding <6 weeks postpartum
-Uncontrolled hypertension
-current breast cancer
-major surgery with prolonged immobilisation
-positive antiphospholipid antibodies
When do you refer a woman earlier for breast cancer screening if she only has one 1st or 2nd degree relative with a history of breast ca?
-age of diagnosis < 40 years
-bilateral breast cancer
-male breast cancer
-ovarian cancer
-Jewish ancestry
-sarcoma in a relative younger than age 45 years
-glioma or childhood adrenal cortical carcinomas
-complicated patterns of multiple cancers at a young age
paternal history of breast cancer
What are considered ‘moderate’ risk factors for pre-eclampsia?
-Age >40
-First pregnancy
-Pregnancy interval of >/= 10yrs
-BMI of 35 or more
-Family history of pre-eclampsia
-Multiple pregnancy
Need to have two risk factors to be started on aspirin 75mg from 12 weeks
What are considered high risk factors for pre-eclampsia?
Hypertensive disease during prev pregnancy
CKD
Autoimmune disorder
Type 1 or 2 diabetes
Chronic hypertension
What obstetric drugs are contraindicated in pre-eclampsia?
Syntometrine
Ergometrine
(Both drugs are associated with hypertension)
When do you start insulin straight away in GDM?
If fasting glucose >7
Or if fasting glucose between 6-6.9, but evidence of complications ef hydraminos or macrosmia
What are risk factors for GDM? When is OGGT offered?
Women with;
-BMI >30
-Previous macrosmic infant
-First degree relative with DM
-Previous GDM
-From a country where DM common (south asia, middle eastern etc)
Offer OGTT at 24-28 weeks
For women who have had GDM before, offer it straight away and then again at 24-28 weeks
What is stepwise management of GDM?
If fasting glucose <7, offer diet and lifestyle modifications for 2 weeks, if targets not met, commence metformin.
Targets:
Fasting glucose 5.3
1hr after meals 7.8
2hrs after meals 6.4
What BP reading in pre-eclampsia means women should be admitted?
> 160/110
Features of severe pre-eclampsia?
-BP >160/110
-Proteinuria
-Headache
-Visual disturbance
-Papilloedema
-RUQ pain/epigastric pain
-Hyperreflexia
-PLT count <100
What is the triad for vasa previa?
Rupture of membranes
Painless PV bleeding
Fetal bradycardia
What is Kleihauer test?
Determines proportion of fetal RBCs present in maternal blood and therefore the calculation of amount of anti-D required for any sensitisation
What does rhesus isoimmunisation/sensitisation mean?
A rhesus negative mother with a rhesus positive baby
(The mum produces IgG antibodies which will affect future pregnancies)