Pharmacology Flashcards
1
Q
Side effects of ACEi
A
Cough (15% of people)
Angioedma (can occur up to 1yr later)
Hyperkalaemia
First dose hypotension
2
Q
Monitoring for ACEi
A
UEC checked before treatment initiated and after changing dose
-Accept creatinine up to 30% baseline and K up to 5.5
3
Q
Which SSRI causes most significant QT prolongation?
A
Citalopram
4
Q
Which SSRI to be used after MI?
A
Sertraline
5
Q
What drugs interact with SSRIs?
A
Warfarin and heparin
MAOI (increase serotonin syndrome)
triptans
NSAID- give PPI to cover
6
Q
SSRIs cause what SE in baby in;
First trimester
Third Trimester
What dose paroxetine specifically cause in baby
A
Congenital Heart defects in first
Persistent pulmonary hypertension in third trimester
Paroxetine increases risks of congenital malformations
