Medicine

Question 1

Most common form of MS?

Answer 1

Relapsing remitting

Question 2

Management of mild to moderate Alzheimers?

Answer 2

donepezil
galantamine
rivastigmine

Question 3

Management of severe Alzheimers

Answer 3

Memantine

Question 4

When is donepezil contraindicated?

Answer 4

In bradycardia
Can also cause insomnia

Question 5

Typical features of frontotemporal dementia?

Answer 5

Onset <65
Insidious
relatively preserved memory and visuospatial skills
Personality change and social problems

Question 6

What bacteria causes gas gangrene/foul smelling black blisters

Answer 6

Clostridium Perfringens

Question 7

What Hep B antibodies are positive if immunised/what antibodies are NEVER positive if only immunised and not been infected

Answer 7

Anti-HBs is positive

IgG Anti-HBc and IgM Anti-HBc are ALWAYS negative

Question 8

Most common SE of meningitis?

Answer 8

Sensorineural hearing loss

Question 9

45y/o man with nausea, pallor and lethargy

Tx?

Answer 9

Hyperkalaemia!

Anyone with K>6.5 or ECG changes;
First give IV calcium gluconate then insulin/dextrose

Question 10

Tx of temporal arteritis?
If vision loss associated?

Answer 10

High dose oral pred

If evolving vision loss give IV methylpred

Question 11

Mx of T2DM with high risk for CVD/established CVD or HF?

Answer 11

Metformin + SGLT2 inhibitor (empagliflozin)

Establish and titrate metformin first

Question 12

What HbA1C level do you add in a second drug for T2DM

Answer 12

58

Question 13

What is an absolute contraindication to use of triptans?

Answer 13

Cardiovascular disease

Question 14

In paracetamol OD what is the criteria for liver transplant?

Answer 14

Arterial pH < 7.3, 24 hours after ingestion

or all of the following:
prothrombin time > 100 seconds
creatinine > 300 µmol/l
grade III or IV encephalopathy