Wk.5 L1 - Intro to Disease

Question 1

LO

Answer 1

1. Be able to define important concepts associated with the study of disease including aetiology, pathogenesis and morphology
2. Explain different approaches to classifying disease and their limitations
3. Develop a systematic approach to consideration of a range disease processes in assessing a lesion

Question 2

Disease

Answer 2

An abnormality in the function
or structure of body organs and systems

Question 3

Pathology

Answer 3

the study of disease and is the
fundamental basis of medicine

Question 4

Lesion

Answer 4

An area of abnormal tissue

Question 5

Studying and understanding disease

Answer 5

• Aetiology
• Pathogenesis
• Morphology
• Clinical Manifestations

Question 6

Aetiology

Answer 6

The initiating cause
- Genetic or Environmental

Question 7

Pathogenesis

Answer 7

Sequence of molectular, biochem and cellular events that lead to disease development

Question 8

Morphology

Answer 8

Structural alterations in cells/ tissue that are characteristic of disease
- Diagnostic of aetiology process

Question 9

Clinical Manifestations

Answer 9

• End result of genetic, biochem and structural changes that lead to symptoms and signs of disease
  As well as its clinical course and outcome

Question 10

Classification of disease

Answer 10

WHO - (ICD-11)

• Ensures same terms are used globally

Question 11

The diverse approach to disease classification

6

Answer 11

• Congenital or acquired
• Infectious or Non-communicable
• Genetic or Environmental
• Neoplastic or non-neoplastic
• Systemic or Organ-specific
• Physical or mental disease

Question 12

Categories of disease processes

Answer 12

Inflammatory
Infectious
Neoplatic
Degenerative
Genetic
Vascular
Metabolic
Nutritional/ Environmental
Traumatic
Immune
Idiopathic
Iatrogenic

Question 13

Summary

Answer 13

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