wk1 pharm FC - Sheet1 Flashcards

1
Q

Therapeutics- branch of medicine dealing with

A

preventing disease and treating the suffering

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2
Q

Pharmacotherapy- application of drugs

A

disease prevention and treatment of suffering

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3
Q

Drugs elicit different responses depending on

A

„Age/ „Gender/ Body mass (weight)/ „Health status/ Genetics

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4
Q

Therapeutic Effect

A

Desirable response

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5
Q

Side/Adverse Effect

A

1 Undesirable response

2 Adverse is more severe

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6
Q

Therapeutic Classification

A

1 Organize drugs by usefulness
2 What drugs do clinically
3 Treating particular diseases
4 Ex. Anticoagulants, antihypertensive, diuretics, & antidepressants

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7
Q

Pharmacologic Classification

A

Based on drug’s mechanism of action
How drugs produce effect
More specific
Ex. Loop diuretics, beta blockers, & ACE inhibitors

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8
Q

Generic Name

A

1 Always lower case

2 Only 1 name per a drug

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9
Q

Trade Name

A

1 Cap first letter in name and has copy right for 17 years

2 Brand name

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10
Q

Controlled substances

A

1 Higher potential for addiction or dependence
2 Addiction- overwhelming feeling to use drug repeatedly
3 Dependence- physiologic or psychological need for a substance
4 Withdrawal- physical signs of discomfort

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11
Q

Drug Schedules

A
I - street drugs
II - methadone
III - low mg of addictive drug
IV - lowest level of prescription drug
V - non prescription drug
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12
Q

Teratogenic drug classification

A

A - Studies in women fail to show risk to fetus; fetal harm unlikely
B - Animal reproduction studies show no fetal risk
C - Studies in animals have revealed adverse effects on fetus or have not been done in animals or women
D - Confirmation of human fetal risk; (benefit may outweigh risk- in life threatening situation)
X - Animal & human studies show fetal abnormalities; drug contraindicated in women who are or may become pregnant

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13
Q

Nursing responsibilities

A
1 Knowledgeable
2 What drug is it?
3 Why is it ordered?
4 How is it supplied by pharmacy?
5 Route of administration?
6 Patient variables
7 Preparation to recognize & react to adverse effects
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14
Q

Allergic Reaction - Hyper response of body defenses to a foreign substance

A
1 Vary in severity
2 Skin rash
3 Itching
4 Edema
5 Runny nose
6 Reddened eyes
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15
Q

Anaphylaxis - Severe allergic reaction involving massive systemic release of histamine & other mediators of inflammation

A

1 Dyspnea
2 Hypotension
3 Tachycardia

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16
Q

Rights of drug administration

A
1 Right patient (National Patient Safety Goals- 2 patient identifiers)
2 Right medication
3 Right dose
4 Right route
5 Right time
6 Right to refuse
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17
Q

3 checks of drug administration

A
  1. Check drug with the MAR
  2. Check drug when preparing it, pouring it, taking it out of container, or connecting it to the patient (IV tubing)
  3. Check drug before administering to patient
18
Q

Patient education

A
1 Name of the drug
2 Why it is necessary
3 Expected drug actions 
4 Side effects
5 Potential interactions (medications, foods, supplements, or alcohol)
19
Q

STAT order

A

must be given w/in 5 mins or less (immediate)

20
Q

ASAP order

A

as soon as possible w/in 30 mins or less

21
Q

Single order

A

only give once

22
Q

PRN order

A

administer as needed per MD order & patient’s condition

23
Q

Routine order

A

can be given 30 mins – 1 hr. before or after

24
Q

Standing order

A

given in advance of a situation that is to be carried out under specific circumstances

25
pharmacokinetics Components
1. Absorption 2. Distribution 3. Metabolism 4. Excretion
26
Enteral Routes
``` 1 Oral (tablets, capsules, sublingual, & buccal) 2 Nasogastric or gastrostomy tube ```
27
Topical Routes
Local use
28
Parenteral Routes
IV, IM, SubQ
29
Topical & Transdermal drugs
1 Avoids first-pass effect of liver 2 Slow absorption 3 Systemic vs. local effect
30
Topical Administration for Transdermal
rotate sites, remove old patch prior to placing new one
31
Topical Administration for Ophthalmic
supine position with head tilted back
32
Topical Administration for Otic
side position, avoid tympanic membrane, pull ear up & backward (children < 3 yrs. pull ear down & back)
33
Topical Administration for Nasal
blow nose prior to med
34
Topical Administration for Vaginal
supine position with knees bent
35
Topical Administration for Rectal
Sims position (on left side), slow deep breaths, insert on exhale
36
Enteral medications Advantages
1 Convenient 2 Least costly 3 Overdose treated by retrieval of undigested medications 4 Safest route (skin barrier not compromised) 5 Uses vast absorptive surfaces
37
Enteral medications Disadvantages
``` 1 Difficulty swallowing 2 Can be inactivated by enzymes 3 First-pass metabolism 4 Some tablets/capsules can’t be opened or crushed 5 Depends on GI motility & mobility ```
38
Types of IV administration | Large Volume Infusion
- Fluid maintenance, replacement, or supplementation | - Ex. Normal Saline 0.9% or Dextrose
39
Types of IV administration | Intermittent Infusion
- Small amount of IV solution arranged with primary large volume infusion or by itself to instill medications - Ex. Piggybacks (IVPB) like Keppra or Zosyn
40
Types of IV administration | IV Push
- Concentrated dose delivered directly to circulation | - Ex. syringe to administer single-dose medications like Zofran, morphine, & Dilaudid
41
First pass effect
- Some oral medications are inactivated on their first pass through the liver prior to reaching target organs - May require higher dose for therapeutic effect or be given by non-enteral route
42
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