Wk 4, Wk 5, Jeopardy Flashcards

1
Q

All of the following are effects of PTH on the kidneys except:

-Increase the reabsorption of renal tubular calcium
-Increase phosphate excretion
-Enhance 1 alpha-hydroxylation of 25-hydroxy vitamin D
-Increased water loss

A

Increased water loss

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2
Q

Rickets is a deficiency in vitamin D in children. What is the corresponding disease in adults?

-Osteogenesis imperfecta
-Osteomalacia
-Ankylosing spondylitis
-Paget disease

A

Osteomalacia

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3
Q

All of the following are functions of calcium except:

-Blood coagulation
-Nerve cell transmission
-Intercellular adhesion
-Muscle repolarization

A

Muscle repolarization

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4
Q

A patient was admitted to the critical care unit of a hospital after their lab values came back as abnormal. PTH values were very low, calcium levels were very high, and Vit D 25(OH) levels were extremely high. It is to be noted that the patient has recently had a change in diet and lifestyle, and the patient claimed historically having a very bad diet. Their general practitioner noted that the patient has recently been taking a large amount of vitamin supplements. Based on this information, what is the most likely cause for the lab values?

-Hypervitaminosis D
-Addison’s Disease
-Primary Hypoparathyroidism
-Grave’s disease

A

Hypervitaminosis D

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5
Q

This is the pathological state in which the heart fails to adequately supply the metabolic needs of the body, typically due to a decrease in pumping function.

-Heart failure
-Heart attack
-Pulmonary embolism
-Angina

A

Heart failure

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6
Q

Which test, if elevated, would provide information about risk for developing coronary artery disease?

-Troponin
-CK-MB
-hs-CRP
-Myoglobin

A

hs-CRP

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7
Q

Which of the following sets of tests would be the most useful in diagnosing an AMI?

-AST, LD, CK-MB
-LD, CK-MB, troponin
-CK-MB, troponin, myoglobin
-LD, troponin, myoglobin

A

CK-MB, troponin, myoglobin

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8
Q

These types of cardiac insults can result in cardiac injury and elevated cardiac biomarkers.

A. Myocarditis
B. Cardiomyopathies
C. Wall stress
D. Myocardial infarction
A, B and D
B, C, and D
All of the above

A

All of the above

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9
Q

If the results for serological markers include:

HBsAg +
Anti-HBs =
Anti-HBc (total) +
HBeAg +
Anti-HBe =

What would that indicate?

-Chronic Hep B, active replicating
-Chronic Hep B, non replicating
-Chronic Hep C
-Early acute infection Hep B

A

Chronic Hep B, active replicating

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10
Q

This type of jaundice is associated with excessive destruction of RBCs without elevation of ALT levels.

-Post hepatic
-Hepatic
-Pre hepatic
-Hepatobiliary

A

Pre hepatic

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11
Q

This is a liver disease characterized by a defective conjugation system and it affects 5% of the population of the U.S.

-Dubin-Johnson Syndrome
-Gilbert’s Syndrome
-Crigler-Najjar Syndrome
-Reyes’s Syndrome

A

Gilbert’s Syndrome

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12
Q

What is the target organ for an infant with kernicterus?

-Brain
-Heart
-Kidney
-Liver

A

Brain

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13
Q

A GFR of 15mL/min/m2 or less, creatinine clearance of <10mL/min, BUN of >50 mg/dL, creatinine >3 mg/dL, potassium > 6.5 mEq/L, and hemoglobin <10 g/dL are all lab test values indicative of what disease state?

-Kidney failure
-Glomerulonephritis
-Nephrotic Syndrome
-Renal Tubular Acidosis

A

Kidney failure

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14
Q

When only the glomerulus has been damaged, ______ proteins can pass through the glomerular membrane to be excreted in urine when it couldn’t before the damage.

A. Small (low molecular weight)
B. Large (high molecular weight)
Both A and B
None of the above

A

B. Large (high molecular weight)

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15
Q

The glomeruli and proximal and distal tubules are located in the renal _____.

-Pelvis
-Medulla
-Cortex
-None of the above

A

Cortex

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16
Q

What is the proper order of structures of a nephron from the blood to the collecting duct?

-Glomerulus, distal tubule, proximal tubule, loop of Henle
- Loop of Henle, glomerulus, proximal tubule, distal tubule
-Glomerulus, proximal tubule, loop of Henle, distal tubule
-Loop of Henle, proximal tubule, distal tubule, glomerulus

A

Glomerulus, proximal tubule, loop of Henle, distal tubule

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17
Q

Which of the three troponins, do we not measure in the lab due to the lack of cardiac specificity?

A

Troponin C

18
Q

This test can be used to help rule out pulmonary embolism.

19
Q

Which test has the widest window of detection for AMIs.

20
Q

This test can be used to help differentiate between heart failure and lung disease.

A

BNP, NT-proBNP

21
Q

Name a test that can be used for cardiovascular risk stratification.

A

hs-CRP
Homocysteine
Troponin

22
Q

Synthesis of Vitamin D begins in the:

23
Q

Common bone disease seen in small statured women.

A

Osteoporosis

24
Q

This hormone regulates blood calcium levels in circulation.

25
What is the active form of Vitamin D called?
1,25(OH)2 Vitamin D
26
Low blood calcium is sensed by what in the parathyroid
CSR-Calcium sensing receptors
27
What is the most common crystal found in kidney stones?
Calcium oxalate
28
What is secreted by the posterior pituitary in response to increased blood osmolality?
AVP/ADH
29
This protein is known to be nephrotoxic when released from the muscles.
Myoglobin
30
What is the term for infection in the kidneys.
Pyelonephritis
31
What test can be used to detect acute kidney injury before creatinine?
Cystatin C
32
How many lobes are there in the liver?
2
33
Cells in the liver responsible for all the major functions.
Hepatocytes
34
What protein binds bilirubin?
Albumin
35
What percentage of people infected with HBV recover within 6 months?
90%
36
What are the two major sources of blood supply to the liver?
Hepatic artery and portal vein
37
The most common cause of liver failure in the U.S.
Alcoholism
38
Where is 1,25 dihydroxyvitamin D formed?
Kidney
39
This aminotransferase is more liver specific.
ALT
40
Performing this test can help distinguish between hepatobiliary disease and osteogenic bone disease.
ALP
41
If a patient has a total bilirubin of 5.9 and a direct bilirubin of 1.6, what is the indirect bilirubin?
4.3