Wk 2: Cell to cell communication, cell division, genetics and inheritance Flashcards

1
Q

Juxtacrine (direct) communication

A

contact dependent signalling
cells need to be in physical contact with each other through signalling membrane proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Indirect comminication

A

no direct contact between communicating cells
requires specific messenger molecules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the 5 main types of indirect cell to cell communication?

A
  1. Endocrine
  2. Neurocrine/neuroendocrine
  3. Paracrine
  4. Autocrine
  5. Neurotransmission
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What types of indirect communication occur via the blood?

A
  1. Endocrine
  2. Neurocrine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What types of indirect communication act on nearby cells?

A
  1. Paracrine
  2. Autocrine
  3. Neurotransmission
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Endocrine cell communication

A

Involves an endocrine cell producing a hormone (e.g adrenal gland producing cortisol) which travels through the bloodstream to reach target cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Neuroendocrine cell communication

A

Involves a neuroendocrine cell (present in the brain) which produces a neurohormone (e.g oxytocin, ADH), then travelling via the blood stream to reach the target cell (e.g kidney)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Paracrine cell communication

A

Involves a paracrine cell which secretes/release a messenger molecule (paracrine molecule) which is then able to act on target cells which are nearby

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Autocrine cell communication

A

Involves an autocrine cell producing an autocrine molecule. Target cells it can act on are only other autocrine cells (e.g immune cells)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Neurotransmission cell communication

A

Involves a neuron which produces the messenger molecule, neurotransmitter. The neurotransmitter can act on several molecule types i.e smooth muscle, gland ot another neuron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Neurosecretion

A

A neuro hormone is released from a neuron and travels via the bloodstream to teach the target cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Neurotransmission

A

A neurotransmitter is released from the neuron and travels via the synapse to reach another neuron, gland or muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Hormones

A

essential in the human body for roles such as:
1. control growth & development
2. Metabolism & energy balance
3. Immune system response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the 2 types of hormones?

A
  1. Water soluble hormones
  2. Lipid soluble hormones
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Water soluble hormones

A

e.g amine, insulin, glucagon
these hormones are secreted through exocytosis, travel through the blood stream, attach to a receptor on the target cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Lipid soluble hormone

A

e.g steroid hormones, thyroid

17
Q

Synergistic target cell response

A

enhance action of another hormone
e.g glucagon and adrenaline both raise blood glucose)

18
Q

Antagonistic target cell response

A

Oppose action of another hormone
e.g glucagon raises blood glucose, insulin reduces it)

19
Q

Ligand receptors

A

specific proteins that function when a specific molecule binds to the receptors

20
Q

Gene

A

unit of heredity
found at a specific location on a chromosome
codes for a specific protein/enzyme to be made

21
Q

Allele

A

alternate DNA sequence version of a gene
2 per gene on autosomes (1 from mum, 1 from dad)

22
Q

Autosome

A

chromosome pairs 1-22 (same in males and females)_

23
Q

Sex chromsome

A

pair 23 (XX in F, XY in M)

24
Q

Mitosis

A
25
Q

Meiosis

A

forms gametes
New cells=different from parent cells (creates 4 genetically different daughter cells)
2 rounds of division; 1st division halves the chromosome number
Prophase I, metaphase I, anaphase I, telophase I & cytokinesis, prophase II, metaphase II, anaphase II, telophase II & cytokinesis

26
Q

Mutation

A

change in the DNA sequence for a gene–>new allele
can be a single nucleotide change/swap or multiple ones