wk 11. novel drug delivery system Flashcards
advantage of lipid nanoparticles
it can encapsulate drugs, enhannce stability and offer targeted delivery
types of LNPs
liposomes - the main guy. has phospholipid bilayers. can trap hydrophyllic drugs inside the aqueous core and hydrophobic within the lipid bilayer.
PEGylated stealth liposomes- modified with polyethylene (peg) to increase circulation time and avoid uptake by immune system
what is role of LPNs in covoid/mrna vaccine
It protects the fragile mRNA from degradation, facilitates mRNA entry into the cell, and contains components that stimulate immune responses.
advantages of controllled release formulation
designed to release drugs slwoly overtime and maintain therapeutic effect for extended period. useful for long term. reduced side effect.
metoprolol
lots of beads covered with polymer membrane that controls the release. improvoes heart rate.
