White Dot Syndromes Flashcards

1
Q

Big Dots

A

Birdshot, APMPPE, Serpiginous

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2
Q

Small Dots

A

MCP, PIC (MEWDS, AZOOR)

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3
Q

Which are bilateral?

A

All except MEWDS and AZOOR

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4
Q

Which are more common in women?

A

Birdshot, MCP/PIC, MEWDS/AZOOR

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5
Q

Goes better without treatment

A

APMPPE, MEWDS

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6
Q

Which require long-term immunosupression?

A

Birdshot, Serpiginous (MCP, AZOOR)

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7
Q

Which cause CNV?

A

Serpiginous, MCP, PIC

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8
Q

In older patients

A

Birdshot and serpiginous

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9
Q

WD at deep choroid

A

Birdshot

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10
Q

WD at RPE/choriocapillaris

A

MCP, PIC, APMPPE, Serpiginous

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11
Q

WD at deep retina/RPE

A

MEWDS, AZOOR

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12
Q

Make scars

A

MCP, PIC, APMPPE, Serpiginous

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13
Q

nyctalopia, decreased color vision

A

Birdshot

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14
Q

classically quiet anterior segment

A

Birdshot

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15
Q

throughout the fundus

A

Birdshot

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16
Q

F=M

A

APMPPE, Serpiginous

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17
Q

flu-like prodrome

A

APMPPE, MEWDS

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18
Q

cerebral vasculitis

A

APMPPE

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19
Q

erythema nodosum

A

APMPPE

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20
Q

geographic pattern

A

Serpiginous

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21
Q

chronic, recurrent

A

Serpiginous, MCP

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22
Q

moderately myopic women

A

PIC

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23
Q

FA mild hyperfluorescence early with increasing hyperfluorescence late

A

PIC

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24
Q

New lesions usually do not appear

A

PIC

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25
Q

Unilateral

A

MEWDS, AZOOR

26
Q

Often have vitreous cells, venous sheathing and RAPD

A

MEWDS

27
Q

Enlarged blind spot

A

MEWDS

28
Q

FA-early hyperflu in wreath-like configuration. Late staining of lesions. Windows defects after resolution

A

MEWDS

29
Q

reduced a-wave in ERG

A

MEWDS

30
Q

may start unilateral but tends to be bilateral asymmetric

A

AZOOR

31
Q

persistent and stabilizes by 6 months in most cases

A

AZOOR

32
Q

Anterior uveitis (50%)

A

MCP

33
Q

ERG remains normal until there is advanced retinal atrophy

A

MCP

34
Q

involvement is predominantly macular

A

PIC

35
Q

in 50% stabilization occurs within 6 months but recovery is infrequent

A

AZOOR

36
Q

EOG shows absence or severe reduction of the light rise

A

AZOOR

37
Q

ERG - a-wave and b-wave amplitude reduction

A

AZOOR

38
Q

cones tend to be affected more than rods

A

AZOOR

39
Q

often temporal

A

AZOOR

40
Q

FAF. Hyperautofluorescent spots corresponding to the macular lesions are visible during active inflammation

A

MEWDS

41
Q

Headache and other neurological symptoms are common and can commence many months after ocular disease onset

A

APMPPE

42
Q

initially at the posterior pole

A

APMPPE

43
Q

HLA-B7 and HLA-DR2

A

APMPPE

44
Q

ICGA demonstrates non-perfusion of the choriocapillaris

A

APMPPE

45
Q

M>F

A

Serpiginous

46
Q

HLA-B7

A

APMPPE (also HLA-DR2), Serpiginous

47
Q

typically starts around the optic disc and extends gradually

A

Serpiginous

48
Q

Recurrence is usually contiguous with or adjacent to existing areas, eventually resulting in extensive chorioretinal atrophy

A

Serpiginous

49
Q

Relentless placoid chorioretinitis (RPC)

A

features of both APMPPE and serpiginous choroiditis

50
Q

Persistent placoid maculopathy (PPM)

A

similar to those of the macular variant of serpiginous choroidopathy, but which generally behave in a more benign fashion unless complicated by CNV

51
Q

Vitiliginous Chorioretinitis

A

Birdshot

52
Q

varying degree of vitritis is commonly found when the disease is active

A

Birdshot

53
Q

ERG and VF are the most useful diagnostic tools

A

Birdshot

54
Q

most numerous nasal to the optic disc

A

Birdshot

55
Q

shimmering photopsias

A

MEWDS

56
Q

100-200 um concentrated around the macula

A

MEWDS

57
Q

typically does not present with vitritis

A

serpiginous, presumed ocular histoplasmosis syndrome

58
Q

hypopigmented choroidal lesions 1/4 to 1/2 optic disc diameter, clustered around the optic nerve, radiating towards the periphery

A

Birdshot

59
Q

ICG multiple hypofluorescent spots, which are typically more numerous than apparent on slit lamp

A

Birdshot

60
Q

ERG prolonged 30 Hz flicker implicit times

A

Birdshot

61
Q

diminished b waves compared to a wave

A

Birdshot