Anterior Flashcards

1
Q

HLA-B27 positivity - how often

A

20% of AAU

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2
Q

Keratic precipitates - what are they made of

A

lymphocytes, plasma cells and macrophages

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3
Q

Koeppe nodules - where

A

on the pupillary margin. may be the site of posterior synechiae formation. both granulomatous and non-granulomatous anterior uveitis

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4
Q

Busacca nodules

A

iris stroma

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5
Q

Iris ‘pearls’ - where

A

lepromatous chronic anterior uveitis

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6
Q

roseolae

A

dilated iris vessels in syphilitic uveitis

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7
Q

HLA-A29

A

Birdshot retinochoroidopathy

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8
Q

HLA-B51 HLA B5

A

Behçet syndrome

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9
Q

HLA-B7 and HLA-DR2

A

(Presumed) ocular histoplasmosis syndrome

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10
Q

HLA-DR4

A

Sympathetic ophthalmitis, Vogt–Koyanagi–Harada syndrome

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11
Q

Non-specific titratable cardiolipin antibody tests

A

RPR and VDRL

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12
Q

ANA

A

juvenile idiopathic arthritism, higher risk of CAU

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13
Q

Mydricaine® No. 2.

A

adrenaline and atropine

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14
Q

Regional steroid injection

A

triamcinolone acetonide, methylprednisolone acetate. The peak action is at about 4 weeks, with a maximum duration of action of around 3 months

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15
Q

Ankylosing spondylitis

A

scleritis, episcleritis, keratitis and mechanical ptosis

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16
Q

Reactive arthritis

A

triad of non-specific urethritis, conjunctivitis (bi) and arthritis. mouth ulceration, circinate balanitis and keratoderma blennorrhagica

17
Q

Psoriatic arthritis

A

AAU occurs in approximately 7%; conjunctivitis, marginal corneal infiltrates and secondary Sjögren syndrome

18
Q

Fuchs uveitis syndrome - virus

A

rubella virus, HSV?, CMV?, toxoplasmosis?

19
Q

Fuchs uveitis syndrome - age and sex

A

average of 40 years old, no gender or racial predilection

20
Q

Fuchs uveitis syndrome - uni or bi

A

affected eye is hypochromic. In blue eyes, stromal atrophy allows the posterior pigmented layer to show through and become the dominant pigmentation - sometimes hyperchromic

21
Q

Russell bodies

A

Tiny crystals in Fuchs uveitis syndrome

22
Q

Amsler sign

A

vessels are typically the source of the haemorrhage sometimes seen on incision into the anterior chamber on cataract surgery in Fuchs uveitis syndrome (also AC paracentesis, ocular trauma, gonioscopy, applanation tonometry, spontaneously)

23
Q

Cataract surgery complications in Fuchs uveitis syndrome

A

Amsler sign, Poor mydriasis and the possibility of postoperative hyphaema, increased inflammation, worsening of glaucoma control and zonular dehiscence

24
Q

most common form of Juvenile idiopathic arthritis

A

Oligoarticular

25
Q

Oligoarticular Juvenile idiopathic arthritis - sex, age, %

A

Girls 5:1 boys, peak age of onset around 2 years, 20% uveitis

26
Q

Polyarticular (RF negative) - joints, sex,

A

five or more joints, F:M 3:1, at any age throughout childhood

27
Q

Polyarticular (RF positive)

A

low risk of uveitis

28
Q

Juvenile idiopathic arthritis - uvetitis, characteristics

A

arthritis first, Injection absent, chronic and non-granulomatous, Posterior synechiae, Band keratopathy and cataract, glaucoma, CMO

29
Q

Neonatal-onset multisystem inflammatory disease

A

Juvenile idiopathic arthritis. skin, joints and CNS. 50% recurrent anterior uveitis. absence of posterior synechiae and no tendency to glaucoma and cataract

30
Q

Whipple disease - ocular manifestations

A

Keratitis, anterior uveitis, vitritis, retinitis, vascular occlusion, and multifocal choroiditis, gaze palsy, nystagmus, ophthalmoplegia, papilloedema and optic atrophy. Oculomasticatory myorhythmia

31
Q

Tubulointerstitial nephritis and uveitis (TINU)

A

adolescent girls; renal disease first, Bilateral non-granulomatous, Disc and macular oedema, Intermediate, posterior or panuveitis may

32
Q

UVEITIS IN RENAL DISEASE

A

Tubulointerstitial nephritis and uveitis (TINU), IgA nephropathy (Berger disease)

33
Q

Birdshot retinochoroidopathy

A

HLA-A29

34
Q

Behçet syndrome

A

HLA-B51 HLA B5

35
Q

(Presumed) ocular histoplasmosis syndrome

A

HLA-B7 and HLA-DR2

36
Q

Sympathetic ophthalmitis, Vogt–Koyanagi–Harada syndrome

A

HLA-DR4

37
Q

Leprosy

A

• Anterior uveitis: chronic and low-grade; classically ‘plasmoid’ (prominent fibrin) • Iris pearls (pathognomonic) • Keratitis • Miosis and iris atrophy

38
Q

HLA-A2

A

Juvenile idiopathic arthritis