What can go wrong in the regeneration process?

Question 1

Neuronal sprouts fail to reach the distal endoneurial tubes (occurs in some cases of severe nerve injuries). This can happen when: The gap between the ________ and _______ nerve stumps is too wide - _________ of the severed nerve fiber ends occurs due to the elastic endoneurium.

Answer 1

proximal and distal
retraction

Question 2

Neuronal sprouts fail to reach the distal endoneurial tubes (occurs in some cases of severe nerve injuries). This can happen when: There may be (name 5 issues) in the gap between proximal and distal nerve stumps.

Answer 2

scar tissue, displaced bone fragments, hemorrhage, edema or inflammation

Question 3

Neuronal sprouts fail to reach the distal endoneurial tubes (occurs in some cases of severe nerve injuries). This can happen when: A crush injury occurs which destroys _____ nerve components including the _______ tubes

Answer 3

distal
endoneurial

Question 4

Neuronal sprouts fail to reach the distal endoneurial tubes (occurs in some cases of severe nerve injuries). This can happen when: In very severe cases the regenerating axons wander into surrounding tissue/scar tissue and form a dense fibrous mass of scar tissue made up of disorganized Schwann cells, capillaries, fibroblasts, macrophages, and collagen fibers at the injury site. This is known as a _________.

Answer 4

NEUROMA

Question 5

T/F Severe nerve injuries may require surgical repair in order to optimize regeneration (to eliminate the gap, reduce scar tissue, remove a neuroma or perform a nerve graft)

Answer 5

True

Question 6

In some cases, regenerating axons enter inappropriate ________ tubes (cross re- innervation) resulting in no further development of the axon.

Answer 6

endoneurial